Protein Alignment Tip60 and Kat7

DIOPT Version :9

• Sequence 1: NP_001259234.1
• Gene: Tip60 / 31362
• FlyBaseID: FBgn0026080
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_851595.1
• Gene: Kat7 / 303470
• RGDID: 727966
• Length: 612
• Species: Rattus norvegicus
• Alignment Length: 572
• Identity: 198/572 - (34%)
• Similarity: 285/572 - (49%)
• Gaps: 127/572 - (22%)

  Fly    65 KRLDEWVNEEDLY-TRKV-------------QFPRRDGSQTGTSTGVTTPQRHHSLAGSVSRPTS 115
            :.|..:..||..| ||:|             ::|.|....:|:.|.............:.....|
  Rat    61 RNLPSFGTEEPAYSTRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQAVDFSDRETKNTADHDES 125

  Fly   116 PQHPGSGALAAIPQTPTGASGSVPPPAGI--PN-----SVAPPGTPSSGGELVNGNNLAAALQKR 173
            |           |:||||.:.|......|  ||     |:|...:...     :|::|:...::|
  Rat   126 P-----------PRTPTGNAPSSESDIDISSPNVSHDESIAKDMSLKD-----SGSDLSHRPKRR 174

  Fly   174 -------INRKRKNHGGSAHGH-----------------HSLTS--------------------- 193
                   .|.|....|.::.||                 |:|::
  Rat   175 RFHESYNFNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECKVRAQSRDKQIEERMLSH 239

  Fly   194 QQQQSHPHPTTPQTPTATPVHV----------TGDGLISGAANDDGDGSQD-GKTPTP------- 240
            :|..::.|.|..|.||...:..          ...||.........:..|. |.|..|
  Rat   240 RQDDNNRHATRHQAPTERQLRYKEKVAELRKKRNSGLSKEQKEKYMEHRQTYGNTREPLLENLTS 304

  Fly   241 -------RQSGSMVTH-------QDDVVTRMKNVEMIELGRHRIKPWYFSPYPQELCQMPCIYIC 291
                   |::.:..:.       |..:......::.|..||:.:..||.||||:|..::..:|:|
  Rat   305 EYDLDLFRRAQARASEDLEKLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMC 369

  Fly   292 EFCLKYRKSRKCLERHLSKCNLRHPPGNEIYRKHTISFFEIDGRKNKVYAQNLCLLAKLFLDHKT 356
            ||||||.||:..|.||::||..:||||:|||||.:||.||:||:|||:|.|||||||||||||||
  Rat   370 EFCLKYMKSQTILRRHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKT 434

  Fly   357 LYYDTDPFLFYVMTEFDSRGFHIVGYFSKEKESTEDYNVACILTMPPYQRKGYGKLLIEFSYELS 421
            ||||.:|||||||||.|:.|.|::|||||||.|..:|||:||||||.|.|:||||:||:|||.||
  Rat   435 LYYDVEPFLFYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLS 499

  Fly   422 KFEGKTGSPEKPLSDLGLLSYRSYWAQTILEIFISQNPSTDGEKPTITINDICECTSIKKEDVIS 486
            |.|.|.||||:|||||||:||||||.:.:|...    .:..|::  |:|.:|.:.|::...|::|
  Rat   500 KVEEKVGSPERPLSDLGLISYRSYWKEVLLRYL----HNFQGKE--ISIKEISQETAVNPVDIVS 558

  Fly   487 TLQNLNLINYYKGQYIV-----CINRVIIEQHRRAMDKRKIRIDSKCLHWTP 533
            |||.|.::.|:||:::|     .|:..|.::.:|:...:  .:|..||.|||
  Rat   559 TLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNK--TMDPSCLKWTP 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tip60	NP_001259234.1	Tudor-knot	23..78	CDD:288553	4/13 (31%)
		Drf_FH1	84..>157	CDD:283903	17/79 (22%)
		PHA01732	139..>196	CDD:222828	15/108 (14%)
		NAT_SF	254..533	CDD:302625	148/283 (52%)
		MOZ_SAS	316..500	CDD:280097	113/183 (62%)
Kat7	NP_851595.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..174		26/128 (20%)
		zf-C2HC	185..211	CDD:279824	4/25 (16%)
		NAT_SF	330..608	CDD:302625	148/285 (52%)
		MOZ_SAS	394..572	CDD:280097	113/183 (62%)
		acetyl-CoA binding. /evidence=ECO:0000250|UniProtKB:O95251	476..478		1/1 (100%)
		acetyl-CoA binding. /evidence=ECO:0000250|UniProtKB:O95251	484..489		3/4 (75%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D285390at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920