DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tip60 and mys-4

DIOPT Version :9

Sequence 1:	NP_001259234.1	Gene:	Tip60 / 31362	FlyBaseID:	FBgn0026080	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	NP_492265.1	Gene:	mys-4 / 183194	WormBaseID:	WBGene00007914	Length:	617	Species:	Caenorhabditis elegans

Alignment Length:	273	Identity:	110/273 - (40%)
Similarity:	161/273 - (58%)	Gaps:	15/273 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   271 KPWYFSPYPQELCQMPCIYICEFCLKYRKSRKCLERHLSKCNLRHPPGNEIYRKHTISFFEIDGR 335
            |..|.|.|.:.|.....:|.|:|||.....::.|..|...||.:||||.||||...::|||:||.
Worm   346 KAIYSSAYEEPLHSSAHLYACKFCLHTTNLKEDLIVHWDICNAKHPPGTEIYRNDGLAFFEVDGA 410

  Fly   336 KNKVYAQNLCLLAKLFLDHKTLYYDTDPFLFYVMTEFDSRGFHIVGYFSKEKESTEDYNVACILT 400
            ..|.|.|:|||::|||:..||||.:.:.|.|||:.|..:.|:.|||||||||..:::.|::|:|.
Worm   411 VQKKYCQDLCLISKLFIASKTLYDEVETFKFYVLCEITTEGYVIVGYFSKEKNPSKNNNLSCLLV 475

  Fly   401 MPPYQRKGYGKLLIEFSYELSKFEGKTGSPEKPLSDLGLLSYRSYWAQTILEIFISQNPSTDGEK 465
            :|..|:.|||:|||:.|||||:.|.:.|.||.||||||:|:||.||..::| .:|.::.:.|
Worm   476 LPMVQKMGYGRLLIDMSYELSRLEMRIGHPEHPLSDLGILAYRGYWRSSLL-CYIREHRNYD--- 536

  Fly   466 PTITINDICECTSIKKEDVISTLQNLNLINYYKGQYIVCINRVIIE----QHRRAMDKRKIRIDS 526
             .:.|.|:|..|.|...|:::.|...|:|....|.|.:.|.:..::    |.||..      :|.
Worm   537 -RLNIKDMCLATRIAPVDIVNQLMLDNMIVLKGGVYSIKIGKRALKFPLSQCRRRF------VDP 594

  Fly   527 KCLHWTPKDWSKR 539
            ..|.|.||..::|
Worm   595 SQLFWKPKPSAER 607

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tip60	NP_001259234.1	Tudor-knot	23..78	CDD:288553
		Drf_FH1	84..>157	CDD:283903
		PHA01732	139..>196	CDD:222828
		NAT_SF	254..533	CDD:302625	107/265 (40%)
		MOZ_SAS	316..500	CDD:280097	83/183 (45%)
mys-4	NP_492265.1	PLN00058	35..117	CDD:177689
		PHD	92..144	CDD:214584
		PHD	147..193	CDD:214584
		NAT_SF	347..603	CDD:302625	107/266 (40%)
		MOZ_SAS	391..565	CDD:280097	82/178 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5027
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D629545at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	5	4.780