Protein Alignment Tip60 and kat6a

DIOPT Version :10

• Sequence 1: NP_572151.1
• Gene: Tip60 / 31362
• FlyBaseID: FBgn0026080
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: XP_031755179.1
• Gene: kat6a / 100496520
• XenbaseID: XB-GENE-6076141
• Length: 1904
• Species: Xenopus tropicalis
• Alignment Length: 486
• Identity: 184/486 - (37%)
• Similarity: 255/486 - (52%)
• Gaps: 71/486 - (14%)

  Fly    76 LYTRKVQFPRRDGSQTGTSTGVTTPQRHHSLAGSVSRPTSPQ---HPGSGALAAIPQTPT----- 132
            |:.:..|..||..:..|      .|:.......|.:.|:..:   .||.|....:....|
 Frog   318 LHKKAAQIRRRYTNPIG------RPKNRLKKQSSTTNPSFGKGRGAPGRGRKRKLSMCSTSSDDD 376

  Fly   133 -------GASGSVP---PPAGIPNSVAPPGTPSSGGELVNGNNLAAALQKRINRKRKNHGGSAHG 187
                   |...|||   ...|:.:.:....|||..|.......|..:||:  :|||   |....|
 Frog   377 RSSDDHRGCGTSVPFNKKTKGLIDGLTKFFTPSPDGRKARAEALDYSLQR--SRKR---GPRKSG 436

  Fly   188 HHSLTSQQ-------QQSHPHPTTPQTPTATPVHVTGDGLISGAANDDGDGSQDGKTPTPRQSGS 245
            .....:|:       .:.||                  |:||   ..:....||.:....::.|
 Frog   437 QADWDNQEGWDCKLDGEDHP------------------GMIS---EKEIALFQDIQEQALQKVG- 479

  Fly   246 MVTHQDDVVTRMKNVEMIELGRHRIKPWYFSPYPQELCQMPCIYICEFCLKYRKSRKCLERHLSK 310
             |....|...|..:|  ||.|::.|:.||.||||||..::|.:|:|||||:|.|||..|::|..|
 Frog   480 -VCGPPDPQVRCPSV--IEFGKYEIQTWYSSPYPQEYTRLPKLYLCEFCLRYMKSRTMLQQHTKK 541

  Fly   311 CNLRHPPGNEIYRKHTISFFEIDGRKNKVYAQNLCLLAKLFLDHKTLYYDTDPFLFYVMTEFDSR 375
            ||..|||.||||||..:|.||:||:.:.:|.|||||||||||||||||||.:||||||:|:.||:
 Frog   542 CNWFHPPANEIYRKDNLSVFEVDGKVSTIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTQNDSK 606

  Fly   376 GFHIVGYFSKEKESTEDYNVACILTMPPYQRKGYGKLLIEFSYELSKFEGKTGSPEKPLSDLGLL 440
            |.|:||||||||...:.|||:||:.:|.|||||||:.||:|||.|||.||:.|||||||||||.|
 Frog   607 GCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGRFLIDFSYLLSKREGQAGSPEKPLSDLGRL 671

  Fly   441 SYRSYWAQTILEIFISQNPSTDGEKPTITINDICECTSIKKEDVISTLQNLNLINYYKGQYIVCI 505
            ||.:||...:||. :..|     .:..::|..:.:.|.|..:|:.:||..|.::. .:|..:|.:
 Frog   672 SYMAYWKSVVLEC-LHHN-----REHQLSIKRLTKLTGICPQDIAATLHQLRMLE-LRGDRVVLV 729

  Fly   506 NR-VIIEQH--RRAMDKRKIRIDSKCLHWTP 533
            .| ..|:.|  |.....|::.:|.:.|.|||
 Frog   730 RREQQIQTHMSRLQARPREVEVDPEALRWTP 760

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tip60	NP_572151.1	CBD_TIP60_like	27..90	CDD:350848	4/13 (31%)
		PLN00104	<255..533	CDD:215056	142/280 (51%)
kat6a	XP_031755179.1	H15	100..160	CDD:197772
		PHD1_MOZ_MORF	203..260	CDD:277090
		PHD2_KAT6A_6B	262..308	CDD:277002
		PLN00104	<486..760	CDD:215056	142/282 (50%)
		PABP-1234	<1746..1875	CDD:130689