Protein Alignment Tip60 and kat8

DIOPT Version :9

• Sequence 1: NP_001259234.1
• Gene: Tip60 / 31362
• FlyBaseID: FBgn0026080
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_997907.1
• Gene: kat8 / 100003790
• ZFINID: ZDB-GENE-030131-7510
• Length: 487
• Species: Danio rerio
• Alignment Length: 512
• Identity: 200/512 - (39%)
• Similarity: 275/512 - (53%)
• Gaps: 138/512 - (26%)

  Fly    32 RMHKTDDWPLAEIVS--IKELDGRRQFYVHYVDFNKRLDEWVNEEDLYTRKVQFPRRDGSQTGTS 94
            |..||  |..||::.  :.|.:||.:||||||.||:||||||.:
Zfish    93 RTDKT--WHSAEVIQSRLNEQEGREEFYVHYVGFNRRLDEWVGK--------------------- 134

  Fly    95 TGVTTPQRHHSLAGSVSRPTSPQHPGSGALAAIPQTPTGASGSVPPPAGIPNSVAPPGTPSSGGE 159
                                        |..|:.:|...|         :..||...|    |||
Zfish   135 ----------------------------ARLALTKTVKDA---------VRKSVEEGG----GGE 158

  Fly   160 LVNGNNLAAALQKRI--NRKRK----NHGGSAHGHHSLTSQQQQSHPHPTTPQTPTATPVHVTGD 218
            ||:      ..:::|  |:|||    ||           .|:..:...|||
Zfish   159 LVD------QPERKITRNQKRKHDEINH-----------VQKTYAEMDPTT-------------- 192

  Fly   219 GLISGAANDDGDGSQDGKTPTPRQSGSMVTHQDDVVTRMKNVEMIELGRHRIKPWYFSPYPQELC 283
                                      :.:..:.:.:|::|.|:.|::|...|..|||||:|::..
Zfish   193 --------------------------AALEKEHEAITKVKYVDKIQIGNFEIDAWYFSPFPEDYG 231

  Fly   284 QMPCIYICEFCLKYRKSRKCLERHLSKCNLRHPPGNEIYRKHTISFFEIDGRKNKVYAQNLCLLA 348
            :.|.::|||:||||.|..|....|||:|..|.|||.|||||:.||.:|:||:.:|:|.|||||||
Zfish   232 KQPKLWICEYCLKYMKYEKTFRYHLSQCQWRQPPGKEIYRKNNISVYEVDGKDHKIYCQNLCLLA 296

  Fly   349 KLFLDHKTLYYDTDPFLFYVMTEFDSRGFHIVGYFSKEKESTEDYNVACILTMPPYQRKGYGKLL 413
            ||||||||||:|.:||:||::||.:.:|.||||||||||||.:..|||||||:|||||:||||.|
Zfish   297 KLFLDHKTLYFDVEPFIFYILTEVNKQGAHIVGYFSKEKESPDGNNVACILTLPPYQRRGYGKFL 361

  Fly   414 IEFSYELSKFEGKTGSPEKPLSDLGLLSYRSYWAQTILEIFISQNPSTDGEKPTITINDICECTS 478
            |.|||||||.|...|||||||||||.|||||||:..:|||.       ...:.|::|.|:.:.||
Zfish   362 IAFSYELSKLESTVGSPEKPLSDLGKLSYRSYWSWVLLEIL-------RDFRGTLSIKDLSQMTS 419

  Fly   479 IKKEDVISTLQNLNLINYYKGQYIVCINRVIIEQHRRAMDKRK--IRIDSKCLHWTP 533
            |.:.|:|||||.||::.|:|||:::|:...::|:|.::...:|  |.:|:.||.|.|
Zfish   420 ITQSDIISTLQPLNMVKYWKGQHVICVTPKLVEEHLKSAQYKKPPITVDTHCLKWAP 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tip60	NP_001259234.1	Tudor-knot	23..78	CDD:288553	23/47 (49%)
		Drf_FH1	84..>157	CDD:283903	7/72 (10%)
		PHA01732	139..>196	CDD:222828	16/62 (26%)
		NAT_SF	254..533	CDD:302625	153/280 (55%)
		MOZ_SAS	316..500	CDD:280097	115/183 (63%)
kat8	NP_997907.1	PLN00104	31..478	CDD:215056	200/512 (39%)
		Tudor-knot	83..139	CDD:288553	24/96 (25%)
		NAT_SF	189..456	CDD:302625	150/313 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5027
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D285390at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100632
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X828
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.720