DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment brn and B3GNT7

DIOPT Version :9

Sequence 1:	NP_476901.1	Gene:	brn / 31358	FlyBaseID:	FBgn0000221	Length:	325	Species:	Drosophila melanogaster
Sequence 2:	NP_660279.1	Gene:	B3GNT7 / 93010	HGNCID:	18811	Length:	401	Species:	Homo sapiens

Alignment Length:	258	Identity:	85/258 - (32%)
Similarity:	129/258 - (50%)	Gaps:	29/258 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 LTMLIKSAVGNSRRREAIRRTWGYE------GRFSDVHLRRVFLLGTAEDSEKD------VAWES 132
            |.:::||.:....||||||:|||.|      ||.:   :|.:||||||...|:.      :|:|.
Human   136 LLVVVKSVITQHDRREAIRQTWGRERQSAGGGRGA---VRTLFLLGTASKQEERTHYQQLLAYED 197

  Fly   133 REHGDILQAEFTDAYFNNTLKTMLGMRWASDQFNRSEFYLFVDDDYYVSAKNVLKFLGRGRQSHQ 197
            |.:|||||..|.|.:||.|||.:..::|.........|....|||.:|:..|:|:||.    ..|
Human   198 RLYGDILQWGFLDTFFNLTLKEIHFLKWLDIYCPHVPFIFKGDDDVFVNPTNLLEFLA----DRQ 258

  Fly   198 P-ELLFAGHVFQ-TSPLRHKFSKWYVSLEEYPFDRWPPYVTAGAFILSQKALRQLYAASVHLPLF 260
            | |.||.|.|.| ..|:|.|.:|:|:....|....:|||...|.|:::....|:|:.|...|.|:
Human   259 PQENLFVGDVLQHARPIRRKDNKYYIPGALYGKASYPPYAGGGGFLMAGSLARRLHHACDTLELY 323

  Fly   261 RFDDVYLGIVALKAGISLQHCDDFRF-------HRPAYKGPDSYSSVIASHEFGDPEEMTRVW 316
            ..|||:||:.....|:.....:.|:.       :....|.|..:.:::..|:. .|.|:..:|
Human   324 PIDDVFLGMCLEVLGVQPTAHEGFKTFGISRNRNSRMNKEPCFFRAMLVVHKL-LPPELLAMW 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
brn	NP_476901.1	Galactosyl_T	92..282	CDD:250845	75/203 (37%)
B3GNT7	NP_660279.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	35..62
B3GNT7	NP_660279.1	Galactosyl_T	148..342	CDD:304462	75/200 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156989
Domainoid	1	1.000	131	1.000	Domainoid score	I5138
eggNOG	1	0.900	-	-		E1_KOG2287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	141	1.000	Inparanoid score	I4482
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1037602at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm40700
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X41
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.800