DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment brn and aars2

DIOPT Version :9

Sequence 1:	NP_476901.1	Gene:	brn / 31358	FlyBaseID:	FBgn0000221	Length:	325	Species:	Drosophila melanogaster
Sequence 2:	XP_001332388.5	Gene:	aars2 / 792787	ZFINID:	ZDB-GENE-041008-213	Length:	1004	Species:	Danio rerio

Alignment Length:	254	Identity:	50/254 - (19%)
Similarity:	81/254 - (31%)	Gaps:	94/254 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 THLHELNFE-RHFHYPLNDDTGSGSASSGLDKFAYLRVPSFTAEVPVDQPARLTMLIKSAVGNSR 92
            |..|.|||. |....|:....||..:::.| :|.:    |....:.|.:..::..|:.:.:
Zfish   643 TATHVLNFALRELLGPIVSQRGSHCSANRL-RFDF----SVKGTLTVSELQKVEELVLNII---- 698

  Fly    93 RREAIRRTWGYEGRFSDVHLRRVFLLGTAEDSEKDVAWESREHGDILQAEFTDAYFNNTLKTMLG 157
            |:.|            |||:..|.|     .|.|.:|                           |
Zfish   699 RQNA------------DVHVEEVPL-----SSAKQIA---------------------------G 719

  Fly   158 MRWASDQFNRSEFYLFVDDDYYVSAKNVLKFLGRGRQSHQP--ELLFAGHVFQTSPLRHKFSKWY 220
            :|...:        |:.|....||....:..|....::.|.  ||....|:.:|..:|.     :
Zfish   720 LRTVDE--------LYPDPVRVVSVAVPVSDLLASERAEQTSVELCCGTHLLRTGAIRD-----F 771

  Fly   221 VSLEEYPFDRWPPYVTAGAFILSQKALRQLYAASVHLPLFRFDDVYLGIVALKAGISLQ 279
            |.:.|                      ||:......:..|..||   .|.|.:||.:||
Zfish   772 VVVSE----------------------RQMMKGVCRIVAFTGDD---AIKAREAGQALQ 805

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
brn	NP_476901.1	Galactosyl_T	92..282	CDD:250845	36/190 (19%)
aars2	XP_001332388.5	PLN02900	41..993	CDD:215487	50/254 (20%)
		AlaRS_core	44..292	CDD:238360
		tRNA_SAD	565..787	CDD:298782	41/231 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000088
OrthoInspector	1	1.000	-	-		otm24800
orthoMCL	1	0.900	-	-		OOG6_100261
Panther	1	1.100	-	-	O	PTHR11214
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X41
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.910