DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment brn and B3gnt3

DIOPT Version :9

Sequence 1:	NP_476901.1	Gene:	brn / 31358	FlyBaseID:	FBgn0000221	Length:	325	Species:	Drosophila melanogaster
Sequence 2:	NP_082465.3	Gene:	B3gnt3 / 72297	MGIID:	2152535	Length:	372	Species:	Mus musculus

Alignment Length:	322	Identity:	99/322 - (30%)
Similarity:	151/322 - (46%)	Gaps:	40/322 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 RCLLVLPLILLVDYCGLLTHLHELNFERHFHYPLNDDTGSGSASSGLDKFAYLRVPSFTAEVPVD 75
            ||...|.:....|:.||..|:.:..|.||..                 .|..||.|..|   ...
Mouse    60 RCRANLSVSSHPDFAGLPLHVRDFLFYRHCR-----------------DFPVLREPRVT---KCA 104

  Fly    76 QPARLTMLIKSAVGNSRRREAIRRTWGYEGRFSDVHLRRVFLLGTAEDSEKD------VAWESRE 134
            :|..|.:.|||:..|..||:.:|.||..|.|.....|||:||:|:..|.::.      :..|:::
Mouse   105 EPVFLLLAIKSSPANYGRRQMLRTTWARERRVRGAPLRRLFLVGSDRDPQQARKYNRLLELEAQK 169

  Fly   135 HGDILQAEFTDAYFNNTLKTMLGMRWASDQFNRSEFYLFVDDDYYVSAKNVLKFLGRGRQSHQPE 199
            :|||||.:|.|::||.|||.:|.:.|.......:.|.|..|||.:....|::.:|    |.|.|:
Mouse   170 YGDILQWDFHDSFFNLTLKQVLFLEWQLTYCTNASFVLNGDDDVFAHTDNMVTYL----QDHDPD 230

  Fly   200 L-LFAGHVFQ-TSPLRHKFSKWYVSLEEYPFDRWPPYVTAGAFILSQKALRQLYAASVHLPLFRF 262
            . ||.||:.| ..|:|..:||:::.......||:|||...|.|:||:..:..|..|:..||:|..
Mouse   231 QHLFVGHLIQNVGPIRVPWSKYFIPALVMAEDRYPPYCGGGGFLLSRFTVAALRRAARVLPMFPI 295

  Fly   263 DDVYLGIVALKAGISLQHCDDFR-------FHRPAYKGPDSYSSVIASHEFGDPEEMTRVWN 317
            |||:||:...:.|::.......|       ..|.:...|..|..::..|.| .|.||..:|:
Mouse   296 DDVFLGMCLQQQGLAPGTHSGVRTAGVFPPSPRVSSFDPCFYRDLLLVHRF-LPFEMLLMWD 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
brn	NP_476901.1	Galactosyl_T	92..282	CDD:250845	68/197 (35%)
B3gnt3	NP_082465.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	31..56
B3gnt3	NP_082465.3	Galactosyl_T	122..311	CDD:389837	68/192 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847379
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1037602at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm57814
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3094
SonicParanoid	1	1.000	-	-		X41
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.780