DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment brn and B3galnt1

DIOPT Version :9

Sequence 1:	NP_476901.1	Gene:	brn / 31358	FlyBaseID:	FBgn0000221	Length:	325	Species:	Drosophila melanogaster
Sequence 2:	NP_064410.1	Gene:	B3galnt1 / 26879	MGIID:	1349405	Length:	331	Species:	Mus musculus

Alignment Length:	253	Identity:	73/253 - (28%)
Similarity:	122/253 - (48%)	Gaps:	33/253 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 LTMLIKSAVGNSRRREAIRRTWGYEGRFSDVHLRRVFLLG-TAEDSEKDVAWESRE----HGDIL 139
            |.:|:.|...:.:.|:|||.|||.:..:....:...|||| .||..:|.:|....:    :|||:
Mouse    80 LVILVTSRPSDVKARQAIRVTWGEKKSWWGYEVLTFFLLGQQAEREDKTLALSLEDEHVLYGDII 144

  Fly   140 QAEFTDAYFNNTLKTMLGMRWASDQFNRSEFYLFVDDDYYVSAKNVLKFLGRGRQSHQPELLFAG 204
            :.:|.|.|.|.||||::..||..:....:::.:..|.|.:::..|::|:|   ...:..|..|.|
Mouse   145 RQDFLDTYNNLTLKTIMAFRWVMEFCPNAKYIMKTDTDVFINTGNLVKYL---LNLNHSEKFFTG 206

  Fly   205 H-VFQTSPLRHKFSKWYVSLEEYPFDRWPPYVTAGAFILSQKALRQLYAASVHLPLFRFDDVYLG 268
            : :......|..|.|.::|.:||||..:|||.:...:|:|...:.::|....|:...:|:|||:|
Mouse   207 YPLIDNYSYRGFFHKNHISYQEYPFKVFPPYCSGLGYIMSGDLVPRVYEMMSHVKPIKFEDVYVG 271

  Fly   269 IV--ALKAGISLQ-----------HCDDFRFHRPAYKGPDSYSSVIASHEFGDPEEMT 313
            |.  .||..|.:.           |.|..:..|           |||:|.|...|.:|
Mouse   272 ICLNLLKVDIHIPEDTNLFFLYRIHLDVCQLRR-----------VIAAHGFSSKEIIT 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
brn	NP_476901.1	Galactosyl_T	92..282	CDD:250845	61/208 (29%)
B3galnt1	NP_064410.1	Galactosyl_T	92..285	CDD:250845	60/195 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847384
Domainoid	1	1.000	126	1.000	Domainoid score	I5388
eggNOG	1	0.900	-	-		E1_KOG2287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1037602at2759
OrthoFinder	1	1.000	-	-		FOG0000088
OrthoInspector	1	1.000	-	-		otm42774
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11214
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X41
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.810