DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment brn and B3galt2

DIOPT Version :9

Sequence 1:	NP_476901.1	Gene:	brn / 31358	FlyBaseID:	FBgn0000221	Length:	325	Species:	Drosophila melanogaster
Sequence 2:	NP_064409.3	Gene:	B3galt2 / 26878	MGIID:	1349461	Length:	422	Species:	Mus musculus

Alignment Length:	293	Identity:	82/293 - (27%)
Similarity:	148/293 - (50%)	Gaps:	42/293 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 DDTGSGSASSGLDKFAYLRVPSFTAEVPVDQPAR-------LTMLIKSAVGNSRRREAIRRTWGY 103
            ::.|:|..:|  ..|.|:          :::|.:       |.:||.:..|....|.|||:|||.
Mouse   124 NEKGTGHPNS--YHFKYI----------INEPEKCQEKSPFLILLIAAEPGQIEARRAIRQTWGN 176

  Fly   104 EGRFSDVHLRRVFLLGTAED----SEKDVAWESREHGDILQAEFTDAYFNNTLKTMLGMRWASDQ 164
            |.....:.:.||||||.:..    .:..:..|||::.||:|.|:.|.|:|.|:||::||.|.:..
Mouse   177 ETLAPGIQIIRVFLLGISIKLNGYLQHAIQEESRQYHDIIQQEYLDTYYNLTIKTLMGMNWVATY 241

  Fly   165 FNRSEFYLFVDDDYYVSAKNVL-KFLGRGRQSHQPEL-----LFAGHVFQ-TSPLRHKFSKWYVS 222
            ...:.:.:..|.|.:|:.:.:: |.|       :|:|     .|.|::.: .:|.|:|.||||:.
Mouse   242 CPHTPYVMKTDSDMFVNTEYLIHKLL-------KPDLPPRHNYFTGYLMRGYAPNRNKDSKWYMP 299

  Fly   223 LEEYPFDRWPPYVTAGAFILSQKALRQLYAASVHLPLFRFDDVYLGIVALKAGIS-LQHCDDFRF 286
            .:.||.:|:|.:.:...::.|.....:::..|:.:.....:|||:||...|..:. :...::|.|
Mouse   300 PDLYPSERYPVFCSGTGYVFSGDLAEKIFKVSLGIRRLHLEDVYVGICLAKLRVDPVPPPNEFVF 364

  Fly   287 H--RPAYKGPDSYSSVIASHEFGDPEEMTRVWN 317
            :  |.:|.. ..||.:|.||:| .|.|:.:.||
Mouse   365 NHWRVSYSS-CKYSHLITSHQF-QPSELIKYWN 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
brn	NP_476901.1	Galactosyl_T	92..282	CDD:250845	58/201 (29%)
B3galt2	NP_064409.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	91..110
B3galt2	NP_064409.3	Galactosyl_T	165..359	CDD:250845	58/200 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847378
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000088
OrthoInspector	1	1.000	-	-		otm42774
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11214
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X41
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.840