DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment brn and B3gnt8

DIOPT Version :9

Sequence 1:	NP_476901.1	Gene:	brn / 31358	FlyBaseID:	FBgn0000221	Length:	325	Species:	Drosophila melanogaster
Sequence 2:	NP_001031817.1	Gene:	B3gnt8 / 232984	MGIID:	2385269	Length:	389	Species:	Mus musculus

Alignment Length:	288	Identity:	86/288 - (29%)
Similarity:	128/288 - (44%)	Gaps:	40/288 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 YPLNDDTGSGS-ASSGLDKFAYLRVPSFTAEVPVDQPARLTMLIKSAVGNSRRREAIRRTWGYEG 105
            :||....|.|| .:|..||           :||.     |.:.:||..|:...|:|:|.|||
Mouse   119 FPLWLPAGEGSPVASCSDK-----------DVPY-----LLLAVKSEPGHFAARQAVRETWG--- 164

  Fly   106 RFSDV-HLRRVFLLGT-----AEDSEKDVAWESREHGDILQAEFTDAYFNNTLKTMLGMRWASDQ 164
              |.| ..|.:||||:     ..|....|.||||.:||:|..:|.|..:|.|||.:|.:.|.|..
Mouse   165 --SPVAGTRLLFLLGSPLGMGGPDLRSLVTWESRRYGDLLLWDFLDVPYNRTLKDLLLLTWLSHH 227

  Fly   165 FNRSEFYLFVDDDYYVSAKNVLKFLGRGRQSHQP---ELLFAGHVF-QTSPLRHKFSKWYVSLEE 225
            .....|.|.|.||.:|....:|:.|    |:..|   ..|:.|.:| |..|||.....:||....
Mouse   228 CPDVNFVLQVQDDAFVHIPALLEHL----QTLPPTWARSLYLGEIFTQAKPLRKPGGPFYVPKTF 288

  Fly   226 YPFDRWPPYVTAGAFILSQKALRQLYAASVHLPLFRFDDVYLGIVALKAGISLQHCDDFRFHRPA 290
            :..| :|.|.:.|.:::|.:....|..|:..:..|.|||||.|......|::.:....|....||
Mouse   289 FEGD-YPAYASGGGYVISGRLAPWLLQAAARVAPFPFDDVYTGFCFRALGLAPRAHPGFLTAWPA 352

  Fly   291 --YKGPDSYSSVIASHEFGDPEEMTRVW 316
              .:.|.:...::..|.. .|::...:|
Mouse   353 ERTRDPCAVRGLLLVHPV-SPQDTIWLW 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
brn	NP_476901.1	Galactosyl_T	92..282	CDD:250845	65/199 (33%)
B3gnt8	NP_001031817.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	36..57
B3gnt8	NP_001031817.1	Galactosyl_T	154..341	CDD:389837	65/196 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847380
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D174158at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X41
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.750