DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment brn and C54C8.3

DIOPT Version :9

Sequence 1:	NP_476901.1	Gene:	brn / 31358	FlyBaseID:	FBgn0000221	Length:	325	Species:	Drosophila melanogaster
Sequence 2:	NP_001361870.1	Gene:	C54C8.3 / 183770	WormBaseID:	WBGene00008291	Length:	226	Species:	Caenorhabditis elegans

Alignment Length:	204	Identity:	49/204 - (24%)
Similarity:	93/204 - (45%)	Gaps:	18/204 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 LRRVFLLGTAEDS---EKDVAWESREHGDILQAEFTDAYFNNTLKTMLGMRWASDQFNRSEFYLF 173
            ::.:||:|.....   :|.|..|::.:|||:..:..|.|...|.|::..:.:...:..|.:....
Worm    14 MKPLFLVGLTPGEYKMKKMVMQEAKLYGDIIVVDMNDNYEELTYKSLAILLYGVSKAPRYQMIGK 78

  Fly   174 VDDDYYVSAKNVLKFLGRGRQSHQPELLFAGHVFQTSP--LRHKFSKWYVSLEEYPFDRWPPYVT 236
            :|:|.......:.:...:|.....| |...|...|:..  .|.|..:|||....|...::|.||:
Worm    79 IDEDVMFFPDKLTELYDQGFIDATP-LRIYGLKMQSGANIFRDKTHRWYVPESSYSCSKFPEYVS 142

  Fly   237 AGAFILSQKALRQLYAASVHLPLFRFDDVYL-GIVALKAGISLQHCDDFRFHRPAYKGPDSY--- 297
            ...::::.:|.:|:..::.:....:.:||:| ||:|...|||:::..:|      ||.|...
Worm   143 GMLYMVTWEAAQQIIKSTKYRDFIQVEDVFLTGILAEDLGISVKNLPEF------YKYPSDIEES 201

  Fly   298 --SSVIASH 304
              ..|||.|
Worm   202 NPGDVIAWH 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
brn	NP_476901.1	Galactosyl_T	92..282	CDD:250845	41/175 (23%)
C54C8.3	NP_001361870.1	Galactosyl_T	1..189	CDD:250845	41/175 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1037602at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100261
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3094
SonicParanoid	1	1.000	-	-		X41
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.750