DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment brn and AgaP_AGAP002097

DIOPT Version :9

Sequence 1:	NP_476901.1	Gene:	brn / 31358	FlyBaseID:	FBgn0000221	Length:	325	Species:	Drosophila melanogaster
Sequence 2:	XP_320943.5	Gene:	AgaP_AGAP002097 / 1281158	VectorBaseID:	AGAP002097	Length:	398	Species:	Anopheles gambiae

Alignment Length:	386	Identity:	154/386 - (39%)
Similarity:	212/386 - (54%)	Gaps:	75/386 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LLVLPLILLVDYCGLLTHLHELNFERHFHYPLNDDT---------GSGSASSGLDKFAYLRVPSF 68
            |..|..:.|:.:.|..||..|.:||..|.||||.|.         |...|...::::.|..:...
Mosquito    15 LAALVGLYLLQFFGAFTHFFEKDFESTFDYPLNGDILSDVYQLRHGQQPARPPINRYNYTYITDC 79

  Fly    69 TAEVPVDQ---PARLTMLIKSAVGNSRRREAIRRTWGYEGRFSDVHLRRVFLLGTAE-------D 123
            ..:...|.   ..||..::|||:.:..||..||:|||||.|||||.:|.||:||.:.       .
Mosquito    80 EHKCKEDDRLIAPRLVFVVKSAIEHFDRRATIRKTWGYERRFSDVKIRTVFVLGRSRVHPNRRLQ 144

  Fly   124 SEKDVAWESREHGDILQAEFTDAYFNNTLKTMLGMRWASDQFNRSEFYLFVDDDYYVSAKNVLKF 188
            |..|:  ||..:.||:||:|.|.|||||:|||.|.|||.....|::||:|.|||:||||||:|::
Mosquito   145 SLVDL--ESSTYRDIVQADFVDDYFNNTIKTMTGFRWAVSYCPRAKFYMFADDDFYVSAKNLLRY 207

  Fly   189 L---------------------------------------------GRGRQSHQ--------PEL 200
            :                                             .|.|...|        |.:
Mosquito   208 VRNPVNYPEYLEETDEALRKLARRLAHTADSNRTAATEEERPAAQQNRTRTKRQLMTEMELPPNV 272

  Fly   201 -LFAGHVFQTSPLRHKFSKWYVSLEEYPFDRWPPYVTAGAFILSQKALRQLYAASVHLPLFRFDD 264
             ||:|.||:::|.||:.|||||||||||:|.||.|||||||:||.:||.::|..|::...|||||
Mosquito   273 KLFSGFVFRSAPHRHRSSKWYVSLEEYPWDMWPTYVTAGAFLLSHEALFEMYYVSMYTKHFRFDD 337

  Fly   265 VYLGIVALKAGISLQHCDDFRFHRPAYKGPDSYSSVIASHEFGDPEEMTRVWNECRSANYA 325
            ::|||||:||||...|.::|.||:..|.||.||..|:|:|.:.:|.|:|:||||.|::.||
Mosquito   338 IFLGIVAMKAGIEPLHSEEFYFHKAPYLGPQSYKYVLATHGYDEPTELTKVWNEIRASGYA 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
brn	NP_476901.1	Galactosyl_T	92..282	CDD:250845	109/250 (44%)
AgaP_AGAP002097	XP_320943.5	Galactosyl_T	106..353	CDD:304462	108/248 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	111	1.000	Domainoid score	I12212
eggNOG	1	0.900	-	-		E1_KOG2287
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H136613
Inparanoid	1	1.050	253	1.000	Inparanoid score	I5575
OMA	1	1.010	-	-		QHG29201
OrthoDB	1	1.010	-	-		D1037602at2759
OrthoFinder	1	1.000	-	-		FOG0000088
OrthoInspector	1	1.000	-	-		oto106803
Panther	1	1.100	-	-	LDO	PTHR11214
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X41
TreeFam	1	0.960	-	-
	13	12.940