DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Xpac and xpa

DIOPT Version :9

Sequence 1:	NP_476866.1	Gene:	Xpac / 31357	FlyBaseID:	FBgn0004832	Length:	296	Species:	Drosophila melanogaster
Sequence 2:	NP_956765.1	Gene:	xpa / 393443	ZFINID:	ZDB-GENE-040426-1205	Length:	549	Species:	Danio rerio

Alignment Length:	280	Identity:	125/280 - (44%)
Similarity:	167/280 - (59%)	Gaps:	34/280 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 STNESAPPAEKKSKLTNAQKARIERNQAKAQKLREAKLVSHPFKELASNKEGGTHPEAALSQGSS 70
            |:|||:      ..||....|:||||:.:|..||:|:|.|.|    :|..||.||.:.|
Zfish    19 SSNESS------MSLTPHMLAKIERNRQRALMLRQARLASRP----SSAVEGATHAKVA------ 67

  Fly    71 VIKVQGTKYIDSGGGFLLEQPVMPTGVGPAGLNKSGEEAPPILDDAIAIPVQYEECLECGDMFAD 135
                   |.||||.||.:|:..         .....:|...:...|..:...|..|.||...|.|
Zfish    68 -------KTIDSGAGFFIEEET---------TEDEQQEKRVVQQPAPVMEPDYLMCEECQKPFMD 116

  Fly   136 SYLFNNFGHSVCDKCRDKDERYALITRTEAKAEYLLKDCDFDKREPKLRYISRKNPHNVRWGEMK 200
            |||.|:|..||||||||.:.::.||:|||||..|||||||.|||||.||:|.||||||.|||:||
Zfish   117 SYLSNSFDLSVCDKCRDNEVKHKLISRTEAKKNYLLKDCDLDKREPPLRFILRKNPHNPRWGDMK 181

  Fly   201 LYLHLQIHQRALEVWGSEEELVRQHEAREDKREEGKARKYNKKMKQLRMEVRSSIYTKKTHEVHE 265
            |||..|:.:|::|||||:|.|....|.||:.:|..|.:::|||:|:||..||||::.|.| .:|:
Zfish   182 LYLKTQVEKRSMEVWGSDEALEEAKETREENKEVQKQKRFNKKVKELRRTVRSSMFKKDT-SIHQ 245

  Fly   266 HEFGPD-TYDEEEDTYTHTC 284
            |::|.| ..|||||:::..|
Zfish   246 HDYGHDELLDEEEDSFSEKC 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Xpac	NP_476866.1	XPA_N	125..154	CDD:279610	18/28 (64%)
		rad14	126..296	CDD:273164	90/160 (56%)
		XPA_C	156..207	CDD:282967	36/50 (72%)
xpa	NP_956765.1	rad14	107..265	CDD:273164	89/158 (56%)
		XPA_N	107..135	CDD:279610	18/27 (67%)
		XPA_C	137..188	CDD:282967	36/50 (72%)
		DUF4585	401..467	CDD:291885
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587042
Domainoid	1	1.000	84	1.000	Domainoid score	I8217
eggNOG	1	0.900	-	-		E1_COG5145
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H37298
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1542306at2759
OrthoFinder	1	1.000	-	-		FOG0005516
OrthoInspector	1	1.000	-	-		oto41659
orthoMCL	1	0.900	-	-		OOG6_104388
Panther	1	1.100	-	-	LDO	PTHR10142
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1053
SonicParanoid	1	1.000	-	-		X5121
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.740