Protein Alignment Cmtr1 and Cmtr1

DIOPT Version :10

• Sequence 1: NP_572148.2
• Gene: Cmtr1 / 31355
• FlyBaseID: FBgn0029693
• Length: 788
• Species: Drosophila melanogaster
• Sequence 2: NP_001014053.1
• Gene: Cmtr1 / 309656
• RGDID: 1307801
• Length: 837
• Species: Rattus norvegicus
• Alignment Length: 778
• Identity: 297/778 - (38%)
• Similarity: 456/778 - (58%)
• Gaps: 55/778 - (7%)

  Fly    25 YSNKAMEMMKKMGYENDKGLGKSNQGRLEPIIAVQQDGRRGFGLKLDTVQSSAG-QW----DP-A 83
            |::.:.::|.|||:...:||||.:|||.:.:....|.||||.||.|........ .|    :| |
  Rat    86 YNSVSQKLMAKMGFREGEGLGKYSQGRKDIVETSNQKGRRGLGLTLQGFDQELNVDWRDEPEPNA 150

  Fly    84 CEELE-IPEPVLWLHNPGSRADAYSLDQLMGHLVTGEKKLTLDGETRYCDPAILHHILNAKTVFD 147
            ||::. .||....:  |.||       ::...:|.|::|:.::.||.:|...:||.:|..|:|||
  Rat   151 CEQVSWFPECTTEI--PDSR-------EMSDWMVVGKRKMVIEDETEFCGEELLHSMLKCKSVFD 206

  Fly   148 DLNDNEKRRARSRCNPFETIRSSIFLNRAAVKMANIDSMCNFMFTNPRDPAGQTLVAPD--ELLY 210
            .|:..|.||||:|.||:|.||...||||||:||||:|.:.:.|||||.|.:|:.|:...  :|||
  Rat   207 ILDGEEMRRARTRANPYEMIRGVFFLNRAAMKMANMDFVFDRMFTNPLDSSGKPLLKESDIDLLY 271

  Fly   211 FTDMCAGPGGFSEYVLYRKSWEAKGFGFTLRGANDFKLEKFFAASPESFDTFY---GVKEDGNIF 272
            |.|:||||||||||||:|:.|.|||||.||:|.||||||.|::||.|.|:.:|   ||..||:|.
  Rat   272 FADVCAGPGGFSEYVLWRRKWHAKGFGMTLKGPNDFKLEDFYSASSELFEPYYGEGGVDGDGDIT 336

  Fly   273 DESNQDSLNEYIRMHTP-QGVHFAMADGGFSVEGQKNIQEILSKQLYLCQFLTALKILRPNGSFV 336
            ...|.::...::..:|. :||||.|||||||||||:|:||||||||.|||||.||.::|..|.||
  Rat   337 RPENINAFRNFVLDNTDRKGVHFVMADGGFSVEGQENLQEILSKQLLLCQFLMALSVVRTGGHFV 401

  Fly   337 CKVFDLFTPFSVGLVYLMYKCFQQIAIIKPNSSRPANSERYLVCKYKRSDAETAGIVAYLNTVNL 401
            ||.|||||||||||:||:|.||:::.:.||.:|||||||||:|||..:...:  .:..||.:||:
  Rat   402 CKTFDLFTPFSVGLIYLLYCCFERVCLFKPVTSRPANSERYVVCKGLKVGID--DVREYLFSVNI 464

  Fly   402 MLSDESQLDENDVLEIFNANELAEDEDFLRYIIDSNNAIGKKQIVGLRKIAAFAQNLELKETKQS 466
            .|:.....| :||..:...:.:..|.:|..|:|.||.:....||..|.||.||.|:..|.|.:|:
  Rat   465 QLNQLRNTD-SDVNLVVPLSVIKGDHEFNDYMIRSNESYCSLQIKALAKIHAFVQDTTLSEPRQA 528

  Fly   467 EVRQECLKRWGLPDKLRQAPENKPTDRLLD--ELLADWANERSWLSLPATEMKGVASLNATIKNV 529
            |:|:|||:.|.:||:.|.||  .|:|....  ||:.|  .:.:..|...|.:  .|.....|:.|
  Rat   529 EIRKECLQLWEIPDRARVAP--SPSDPKFKFFELIKD--TDINIFSYKPTLL--TAKTLEKIRPV 587

  Fly   530 ADWYFVPVGREETNINACSLFLCKSRGNLLRYT----EHKKWELVETAFEVQPRSIFFGQIVYEF 590
            .::..:..|.|:..:    |.|.||:    .||    :..:|..::...|:...::...:||:|.
  Rat   588 LEYRCMVSGSEQKFL----LGLGKSQ----IYTWDGRQSDRWVKLDLKTELPRDTLLCVEIVHEL 644

  Fly   591 YGEGRTIQRMAALHIIDGICLGGVDIRRRPYRERVSMCDKFARSLNKPYRKDRTFGALRSKPLFR 655
            .|||:..::::|:||:|.:.|.|.|:|.:.:.:|:.:.:||.::::||.|.|  ...:|.|.::|
  Rat   645 KGEGKAQRKISAIHILDVLVLNGSDVREQHFNQRIQLAEKFVKAVSKPSRPD--MNPIRVKEVYR 707

  Fly   656 LQDMGSFFANMRHYVLKDN--SQRLGFALDDNKFFVPGGIMMFCELTNNYVSAHSRSRGQLYYFN 718
            |::|...|..:...::|.:  :.:|.:...|::.|||.|:.:...:|..:..|.|:...:.:::|
  Rat   708 LEEMEKIFVRLEMKLIKGSGGTPKLSYTGRDDRHFVPTGVYIVRTVTEPWTMAFSKGWKKKFFYN 772

  Fly   719 VRNKESYYKDQIPRNKADEIFASFRFSFSCRLLWKWTDLRQVEELATEDNPKILFRSDFVKFI 781
            .:..||::  .:|    .|..|.|...:..||.|:|.|...:.:.....:|..|.:.|.:.||
  Rat   773 KKTGESFF--TLP----PESIAPFHTCYYTRLFWEWGDGFHMRDSQKPQDPDKLSKEDVLSFI 829

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cmtr1	NP_572148.2	G-patch	25..69	CDD:396249	18/43 (42%)
		FtsJ	172..383	CDD:426399	132/216 (61%)
Cmtr1	NP_001014053.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..67
		Bipartite nuclear localization signal. /evidence=ECO:0000255|PROSITE-ProRule:PRU00768	2..18
		G-patch	86..128	CDD:396249	17/41 (41%)
		FtsJ	231..447	CDD:426399	132/221 (60%)
		Adenylation_DNA_ligase_like	<622..739	CDD:448381	32/122 (26%)
		Interaction with POLR2A. /evidence=ECO:0000250	726..834		23/109 (21%)