Protein Alignment CG43689 and Pits

DIOPT Version :10

• Sequence 1: NP_001259230.1
• Gene: CG43689 / 31353
• FlyBaseID: FBgn0263772
• Length: 1706
• Species: Drosophila melanogaster
• Sequence 2: NP_001138192.1
• Gene: Pits / 32205
• FlyBaseID: FBgn0030400
• Length: 630
• Species: Drosophila melanogaster
• Alignment Length: 735
• Identity: 158/735 - (21%)
• Similarity: 205/735 - (27%)
• Gaps: 342/735 - (46%)

  Fly   873 QQQQQQHHQQQQQQQQQQ-------------QQQQQQQHGKQSSSPAPNVSGVPAVDLSGSTSVT 924
            :|.::.|...:||:..:.             |||||.|.|     |.|.
  Fly    51 RQMKRLHPASKQQRSHENGEVSAAAAAAVVLQQQQQLQVG-----PVPG---------------- 94

  Fly   925 SSSPHGFNSPASHNQYTAQRMGNGSPQPGASPNIASPQVPSPQGQTLDLSVTRLPHSIITSPQYG 989
                   ..|.||      |.|.|...|||.|....|. ||..|     |::.|.:::..:   .
  Fly    95 -------QGPGSH------RGGGGGGPPGAPPGSGGPG-PSGAG-----SLSSLGNAVAAA---A 137

  Fly   990 ADGLVVGHAQGFVSGATGPLGPGNGGPPRSPQMEPVDFSGPPRPLGFGLVGHISGPRPYSRESTP 1054
            |...|..|.|                   .|...||...||  ||.:          |...|..|
  Fly   138 AAAAVHHHHQ-------------------MPYQMPVPRIGP--PLDY----------PVKLEDAP 171

  Fly  1055 DSGGSHYIETYRDPSGYSPHPGYGMVVQSDYPPAGYHGYGPAAYQCSNPYATAVGPGGYPTPVSG 1119
             .||...:..    |..:||         ..||....|.|.|.            .||.||..||
  Fly   172 -GGGVRPVRI----SHMTPH---------HLPPNATRGGGGAP------------GGGVPTAGSG 210

  Fly  1120 GYSPSPATCYSM--PPPQHI----------PQHDKSKDGLTGCSRSDRNHLQSHSQELKCPTPGC 1172
            |.|..||...::  ||.:.:          ..|..:.||..|.|.|....:..     .|| ||.
  Fly   211 GGSLPPALSVNLKRPPSEDVDVDVSQQQQQSGHGLAPDGSAGNSLSAGGGVSG-----GCP-PGI 269

  Fly  1173 ------DGSGHVTG--------------NYSSHRSLSGCPRANKPKSKP---------------- 1201
                  |.|| |.|              :|...|.|||.....:|...|
  Fly   270 KRSAMDDPSG-VGGRPPLTRGESLPAAVSYVPERQLSGLRDKQQPVRAPSFDASTFKAANPIPNP 333

  Fly  1202 ----------------RDGQDSEPLRCPIP-----GCDGSGHSTGKFLSHRSASGCPIANRNKMR 1245
                            |:|  |.|...|:|     ..:.||.|:|     |.:||
  Fly   334 IPHHLHIAEHMSPASRRNG--SSPPSGPLPPRSVHSPNSSGSSSG-----RRSSG---------- 381

  Fly  1246 VLEAGGTVEQHKAAVAAATAMKFDACTTVGSQGIKKPKFDEVTMVYPKGYTGGS--GLDIVMGGV 1308
                    .:|.::            |||.|..:                 |||  |..:|.||:
  Fly   382 --------SRHVSS------------TTVTSSEV-----------------GGSNPGQAVVAGGL 409

  Fly  1309 GSSVGVGLGLNV----------GIGVTSSSS-----SSSSAGGNNNNSG----SSNTVVTDKNPS 1354
            |...|.|.|.|.          |.|..|.:|     |:||..|.|...|    :.|:|..|.:|:
  Fly   410 GGGGGGGPGSNAASGQLGGPSGGSGQLSCTSGGPGGSASSGSGGNGAIGPASMAPNSVAGDGSPA 474

  Fly  1355 GGGASSGANGSDDLNTLEAEISELQRENARVESQMMRLKSDINAMESQLSTSDREASPLSGHQQQ 1419
            ||...||:|||.
  Fly   475 GGNGPSGSNGSG----------------------------------------------------- 486

  Fly  1420 QQRSSVALASPSGQSPFASVSSTSGASSSVSGATTNSNNNNSSSGGGTTNANDLNHSISNLAPSS 1484
                             .||:...|:|.|..|   .......:||||:..:..|..     ||.|
  Fly   487 -----------------GSVNPGPGSSGSQGG---GGGGTPLASGGGSAGSGGLGG-----APGS 526

  Fly  1485 GSNPNQAIEGVGGAPPNANL 1504
            .:..|.|......|..||.|
  Fly   527 SAASNSAAAAAAAAAQNATL 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43689	NP_001259230.1	zf-C2HC	415..443	CDD:460240
		zf-C2HC	1166..1194	CDD:460240	14/47 (30%)
		zf-C2HC	1211..1239	CDD:460240	9/32 (28%)
Pits	NP_001138192.1	IRF-2BP1_2	6..57	CDD:463250	1/5 (20%)
		vRING-HC_IRF2BP1-like	546..602	CDD:438174	1/1 (100%)