Protein Alignment CG6414 and Ache

DIOPT Version :10

• Sequence 1: NP_570089.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: XP_038945765.1
• Gene: Ache / 83817
• RGDID: 69313
• Length: 616
• Species: Rattus norvegicus
• Alignment Length: 622
• Identity: 205/622 - (32%)
• Similarity: 283/622 - (45%)
• Gaps: 124/622 - (19%)

  Fly    22 SDGRNSQCLHVRLSHGGWLIGRHLTTHNGRHMRAFMGVPYAEPPLDDLRFRPPVPKAPWEGERLA 86
            ::||....|.||: .||.|.|..|....| .:.||:|:|:||||:...||.||.||.||.|
  Rat    31 AEGREDPQLLVRV-RGGQLRGIRLKAPGG-PVSAFLGIPFAEPPVGSRRFMPPEPKRPWSG---- 89

  Fly    87 IKDAP----ICLQR--------------DPFRRDMILEGSEDCLYLNVYTPERPRTNGSLPVMVW 133
            |.||.    :|.|.              :|.|     |.|||||||||:|| .||.....||::|
  Rat    90 ILDATTFQNVCYQYVDTLYPGFEGTEMWNPNR-----ELSEDCLYLNVWTP-YPRPTSPTPVLIW 148

  Fly   134 FHGGGWQCGSGISSFYGPDFLLD-HDIVLVSANFRLGPLGFLSTE-TLDCPGNNGLKDQLEVLHW 196
            .:|||:..|:.....|...||.. ...||||.|:|:|..|||:.. :.|.|||.||.||...|.|
  Rat   149 IYGGGFYSGASSLDVYDGRFLAQVEGTVLVSMNYRVGTFGFLALPGSRDAPGNVGLLDQRLALQW 213

  Fly   197 VRANIASFGGDPNSVTVFGESAGGASVTYHMLSEKSRGLLHRGIAQSGTYFNPWAQPAHKGVAAG 261
            |:.|||:|||||.|||:||||||.|||..|:||..||.|.||.:.||||...||| ....|.|..
  Rat   214 VQENIAAFGGDPMSVTLFGESAGAASVGMHILSLPSRSLFHRAVLQSGTPNGPWA-TVSAGEARR 277

  Fly   262 RATKLAQIVGC---GNAGEWPEKLECLRKKPAEDIVASLYDMFVWDFDPMIPFPPVVEPEHDGAF 323
            |||.||::|||   |..|...|.:.|||.:||:|:|...:.:...:......|.|||    ||.|
  Rat   278 RATLLARLVGCPPGGAGGNDTELISCLRTRPAQDLVDHEWHVLPQESIFRFSFVPVV----DGDF 338

  Fly   324 LTVAPRQAAKPHGLQ-LPLMVGATAEEG-----------------LLKTAALL-----NLPQ--- 362
            |:..|.........| |.::||...:||                 |:..|..|     .:||
  Rat   339 LSDTPEALINTGDFQDLQVLVGVVKDEGSYFLVYGVPGFSKDNESLISRAQFLAGVRIGVPQASD 403

  Fly   363 LLAEFKSQFEQVLPVVLNYDHHDDSVRQTITQRIESFYFKSGHDYDKANHQN-LTDLISDGWFVA 426
            |.||         .|||   |:.|.:                |..|.|:.:: ::.::.|...|.
  Rat   404 LAAE---------AVVL---HYTDWL----------------HPEDPAHLRDAMSAVVGDHNVVC 440

  Fly   427 GIDEYLRLRMSQEDVAPTYVYLFDHKGAASFTEIFKGGRNEFYGACHAEELQYLFPIGRELFVSA 491
            .:.: |..|::.:. |..|.|:|:|:.:.....:       :.|..|..|::::|  |..|..|.
  Rat   441 PVAQ-LAGRLAAQG-ARVYAYIFEHRASTLTWPL-------WMGVPHGYEIEFIF--GLPLDPSL 494

  Fly   492 VPTQKDLELRELMLHLWVSFAKTGNPNPTNVSFHLPNWSPASSYPVEFARLGTKMEDSASIFRLE 556
            ..|.::....:.::..|.:||:||:||....| ..|.|.|.::...::..|..|.      ..:.
  Rat   495 NYTVEERIFAQRLMKYWTNFARTGDPNDPRDS-KSPRWPPYTTAAQQYVSLNLKP------LEVR 552

  Fly   557 NELMQHRVDFWRDLQPHLPA-----------SHAHNE 582
            ..|......||....|.|.:           |.||.|
  Rat   553 RGLRAQTCAFWNRFLPKLLSATATEVPCTCPSPAHGE 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_570089.1	COesterase	28..567	CDD:395084	195/588 (33%)
Ache	XP_038945765.1	COesterase	37..563	CDD:395084	195/588 (33%)