Protein Alignment CG6414 and Ces1h

DIOPT Version :10

• Sequence 1: NP_570089.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_001357759.1
• Gene: Ces1h / 75704
• MGIID: 1922954
• Length: 562
• Species: Mus musculus
• Alignment Length: 618
• Identity: 186/618 - (30%)
• Similarity: 279/618 - (45%)
• Gaps: 107/618 - (17%)

  Fly    12 VILLCICIQWSDGRNSQCLHVRLSHGGWLIGRHLTTHN-GRHMRAFMGVPYAEPPLDDLRFRPPV 75
            :|||.:......|..|....|..:||. ::|::::... .:.:..|:|||:|:|||..|||.||.
Mouse     6 LILLSLSAMAWGGYPSSPPVVNTTHGK-VLGKYISLEGFTQPVAVFLGVPFAKPPLGSLRFAPPQ 69

  Fly    76 PKAPWEGERLAIKDAPICLQRDPFRRDMI------------LEGSEDCLYLNVYTP-ERPRTNGS 127
            |..||...:.|....|:|.| |.....|:            |..|||||||||||| :..:....
Mouse    70 PPEPWSFVKNATSYPPMCSQ-DAVLGQMVNDLIINNKEKIRLRFSEDCLYLNVYTPVDLMKNTNR 133

  Fly   128 LPVMVWFHGGGWQCGSGISSFYGPDFLLDHDIVLVSANFRLGPLGFLSTETLDCPGNNGLKDQLE 192
            ||||||.||||...| |.|::.|.......::|:|:..:||...||.||......||.|..|||.
Mouse   134 LPVMVWIHGGGLVVG-GASAYDGRTLSAHENVVVVTIQYRLAIWGFFSTGDEHSRGNWGHLDQLA 197

  Fly   193 VLHWVRANIASFGGDPNSVTVFGESAGGASVTYHMLSEKSRGLLHRGIAQSGTYFNP--WAQPAH 255
            .|||::.|||:|||||.|||:||:||||.||:..:||..::.|.||.|:|||..|..  :.:.|.
Mouse   198 ALHWIQDNIANFGGDPGSVTIFGQSAGGESVSVLVLSPLAKNLFHRAISQSGVVFTSGLFMEDAS 262

  Fly   256 K-----GVAAGRATKLAQIVGCGNAGEWPEKLECLRKKPAEDIVASLYDMFVWDFDPM------I 309
            .     .|.||..|..:.::           :.|||:|..|:::..:..|.::..|..      .
Mouse   263 SVTEQIAVTAGCKTTTSAVI-----------VHCLRQKTEEELLEIMQKMNLFKLDAQENTKKNY 316

  Fly   310 PFPPVVEPEHDGAFLTVAPRQAAKPHGLQLPLMVGATAEEGLLKTAALLNLPQLLAEFKSQFEQV 374
            ||.|.|   .||..|..||                    |.:|.......:|.::...|.:|...
Mouse   317 PFLPTV---LDGVVLPKAP--------------------EAILAEKNFNTVPYIVGINKQEFGWT 358

  Fly   375 LPVVLNYDHHDDSVRQTITQ---RIESFYFKSGHD--------YDKANH---QN---LTDLISDG 422
            ||:::.:...|..:.:.:..   |..:::|....|        |.|...   ||   |..||.|.
Mouse   359 LPMIMEFPPTDVKLDKKVISLFLRKLAYFFNIPEDGIPVAIEKYSKGTDDPIQNRVWLLQLIGDV 423

  Fly   423 WFVAGIDEYLRLRMSQEDVAPTYVYLFDHKGAASFTEIFKGGRNEFYGACHAEELQYLF--PIGR 485
            .|  ||...:..|..::..||||:|.|..:  .||:...|   .:.....|.:|:..:|  ||.|
Mouse   424 MF--GIPSVIVSRGHRDAGAPTYMYEFQSR--PSFSSELK---PKTVTGDHGDEVYSVFGAPILR 481

  Fly   486 ELFVSAVPTQKDLELRELMLHLWVSFAKTGNPNPTNVSFHLPNWSPASSYPVEFARLGTKMEDSA 550
            |     ..:::::.|.::|:..|.:||:.||||...    ||:| |..:....:.::|...:.:.
Mouse   482 E-----GSSEEEINLSKMMMKFWANFARNGNPNGQG----LPHW-PEYNQKKGYLQIGATTQQAQ 536

  Fly   551 SIFRLENELMQHRVDFWRDLQPHLPASHAHNEL 583
            .       |....|..|.:|:...|....|.||
Mouse   537 G-------LKDKEVSLWTELRAKKPPQTGHTEL 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_570089.1	COesterase	28..567	CDD:395084	175/584 (30%)
Ces1h	NP_001357759.1	COesterase	22..546	CDD:395084	175/584 (30%)