DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6414 and LOC688542

DIOPT Version :9

Sequence 1:	NP_001303565.1	Gene:	CG6414 / 31352	FlyBaseID:	FBgn0029690	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	XP_038954018.1	Gene:	LOC688542 / 688542	RGDID:	1587637	Length:	559	Species:	Rattus norvegicus

Alignment Length:	621	Identity:	182/621 - (29%)
Similarity:	277/621 - (44%)	Gaps:	127/621 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 VILLCICIQWSDGRNSQCLHVRLSHGGWLIGRHLTTHNGRHMR-------AFMGVPYAEPPLDDL 69
            ::||.:.::..|..:.    :|.:|.|.:.|..:      |::       .|:|:|:|:||:..|
  Rat    17 LLLLVLHVRGQDSASP----IRNTHTGQVRGSLV------HVKDTDIDVHTFLGIPFAKPPVGPL 71

  Fly    70 RFRPPVPKAPWEGERLAIKDAPICLQRDPF--RRDM--------ILEGSEDCLYLNVYTPERPRT 124
            ||.||....||.|.|.|.....:|||.|..  ..||        .:..||||||||:|.|.....
  Rat    72 RFAPPEAPEPWSGVRDATSHPAMCLQNDNMMGSEDMKIMKLILPPISMSEDCLYLNIYAPTHAHE 136

  Fly   125 NGSLPVMVWFHGGGWQCGSGISSFY-GPDFLLDHDIVLVSANFRLGPLGFLSTETLDCPGNNGLK 188
            ..:||||||.|||....  |::|.| |.......|:|:|:..:|||.|||.||......||.|..
  Rat   137 GSNLPVMVWIHGGALTV--GMASMYDGSMLAATEDVVVVTIQYRLGVLGFFSTGDEHARGNWGYL 199

  Fly   189 DQLEVLHWVRANIASFGGDPNSVTVFGESAGGASVTYHMLSEKSRGLLHRGIAQSGTYFNPWAQP 253
            ||:..|.||:.|||.|||:||.||:|||||||.||:.|::|..|:||.|..|.:||....|
  Rat   200 DQVAALRWVQQNIAHFGGNPNRVTIFGESAGGTSVSSHVVSPMSQGLFHGAIMESGVVVLP---- 260

  Fly   254 AHKGVAAGRATKL-----AQIVGCGNAGEWPEKLECLRKKPAEDIVASLYDMFVWDFDPMIPFPP 313
                ....|::::     |.:.||. |.:....::|||.|...:|:         |.:.:....|
  Rat   261 ----DLISRSSEMVYRIVANLSGCA-AVDSETLMQCLRGKSEAEIL---------DINKVFKIIP 311

  Fly   314 VVEPEHDGAFLTVAPRQAAKPHGLQLPLMVGATAEEGLLKTAALLNLPQLLAEFKSQFEQVLPVV 378
            .|.   ||.||...|::                    ||.:|....:|.::.....::..:||::
  Rat   312 AVV---DGEFLPKHPQE--------------------LLASANFHRVPSIIGINNDEYGWILPMI 353

  Fly   379 LNYDHH-DDSVRQTITQRIESFYFK---------------SGHDYD-KANHQNLTDLISDGWFVA 426
            .:.... ::..|:|:...::|...|               .|...| |.......:::.|..||.
  Rat   354 FDSAQKIEEITRKTLPTVLKSTALKMMLPPECGDLLMEEYMGDTEDPKTLQAQFREMMGDFMFVI 418

  Fly   427 GIDEYLRLRMSQEDVAPTYVYLFDHKGAASFTEIFKGGRNEFYGACHAEELQYLFP--IGRELFV 489
               ..|::...|...||.|.|.|.|:  :||   ||..:.....|.|.:|:..:|.  :|...|
  Rat   419 ---PALQVAHFQRSHAPVYFYEFQHR--SSF---FKDVKPPHVKADHGDEVFLVFGYLVGDIKF- 474

  Fly   490 SAVPTQKDLEL--RELMLHLWVSFAKTGNPNPTNVSFHLPNWSPASSYPVEFARLGTKMEDSASI 552
               |..::.||  |::|.: |.:||:.||||    |..||:| |...:..::.:|    :...|:
  Rat   475 ---PHTEEEELLSRKIMKY-WANFARHGNPN----SEGLPHW-PVMDHDDQYLQL----DIQPSV 526

  Fly   553 FRLENELMQHRVDFW-----RDLQPHLPASHAHNEL 583
            .|   .|...|:.||     :.:|....|...|.||
  Rat   527 GR---ALKARRLKFWTKTLPQKIQELKGAQERHREL 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_001303565.1	COesterase	36..567	CDD:278561	171/574 (30%)
CG6414	NP_001303565.1	Aes	<116..>254	CDD:223730	63/138 (46%)
LOC688542	XP_038954018.1	COesterase	30..538	CDD:395084	172/585 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810