Protein Alignment CG6414 and Aadac

DIOPT Version :10

• Sequence 1: NP_570089.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_075872.1
• Gene: Aadac / 67758
• MGIID: 1915008
• Length: 398
• Species: Mus musculus
• Alignment Length: 232
• Identity: 55/232 - (23%)
• Similarity: 90/232 - (38%)
• Gaps: 73/232 - (31%)

  Fly    74 PVPKA---PWE-----------------GERLAIK------DAPICLQRDPFRRD---MILEGSE 109
            |:|.|   ||:                 ||.|.|.      ...:..|..|...|   .::|.:.
Mouse    21 PLPDAIEEPWKVVWETAFVKIGTDLASFGELLGISHFMETIQLLMSFQEVPPTSDEHVTVMETAF 85

  Fly   110 DCLYLNVYTPERPRTNGSLPV---MVWFHGGGWQCGSGISSFYGPDFL---LDH--DIVLVSANF 166
            |.:.:.:|.|:|.    |:.:   :.:.|||||..||  ::.:..|.|   ..|  |.|:||.::
Mouse    86 DSVPVRIYIPKRK----SMALRRGLFYIHGGGWCLGS--AAHFSYDTLSRWTAHKLDAVVVSTDY 144

  Fly   167 RLGPLGFLSTETLDCPGNNGLKDQLEVLHWVRAN--IASFGGDPNSVTVFGESAGG---ASVTYH 226
            .|.|......:         .:|....|.|....  :..:|.||..|.|.|:||||   |:||..
Mouse   145 GLAPKHHFPRQ---------FEDVYRSLRWFLQEDVLEKYGVDPRRVGVSGDSAGGNLAAAVTQQ 200

  Fly   227 MLSE-------KSRGLLHRGI---------AQSGTYF 247
            ::.:       |.:.|::..:         .|.|::|
Mouse   201 LIQDPDVKIKLKVQALIYPALQALDTNVPSQQEGSHF 237

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_570089.1	COesterase	28..567	CDD:395084	55/232 (24%)
Aadac	NP_075872.1	Abhydrolase_3	106..356	CDD:400284	37/143 (26%)
		Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion hole. /evidence=ECO:0000250|UniProtKB:Q5NUF3	110..112		1/1 (100%)