DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6414 and Aadac

DIOPT Version :10

Sequence 1:NP_570089.1 Gene:CG6414 / 31352 FlyBaseID:FBgn0029690 Length:583 Species:Drosophila melanogaster
Sequence 2:NP_065413.1 Gene:Aadac / 57300 RGDID:631440 Length:398 Species:Rattus norvegicus


Alignment Length:140 Identity:38/140 - (27%)
Similarity:62/140 - (44%) Gaps:28/140 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   104 ILEGSEDCLYLNVYTPERPRT---NGSLPVMVWFHGGGWQCGSGISSFYGPDFLLDH-----DIV 160
            ::|...:.:.:.:|.|:|..|   .|    :.:.|||||..||  ::::..|.|...     |.|
  Rat    80 VMETDFNSVPVRIYIPKRKSTTLRRG----LFFIHGGGWCLGS--AAYFMYDTLSRRTAHRLDAV 138

  Fly   161 LVSANFRLGPLGFLSTETLDCPGNNGLKDQLEVLHWVRAN--IASFGGDPNSVTVFGESAGG--- 220
            :||.::.|.|......:         .:|....|.|....  :..:|.||..|.|.|:||||   
  Rat   139 VVSTDYGLAPKYHFPKQ---------FEDVYHSLRWFLQEDILEKYGVDPRRVGVSGDSAGGNLT 194

  Fly   221 ASVTYHMLSE 230
            |:||..:|.:
  Rat   195 AAVTQQILQD 204

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6414NP_570089.1 COesterase 28..567 CDD:395084 38/140 (27%)
AadacNP_065413.1 Abhydrolase_3 106..373 CDD:400284 32/110 (29%)
Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion hole. /evidence=ECO:0000250|UniProtKB:Q5NUF3 110..112 1/1 (100%)

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