Protein Alignment CG6414 and nlgn2a

DIOPT Version :10

• Sequence 1: NP_570089.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: XP_009301340.1
• Gene: nlgn2a / 556158
• ZFINID: ZDB-GENE-090918-2
• Length: 828
• Species: Danio rerio
• Alignment Length: 612
• Identity: 184/612 - (30%)
• Similarity: 266/612 - (43%)
• Gaps: 147/612 - (24%)

  Fly    56 FMGVPYAEPPLDDLRFRPPVPKAPWEGERLAIKDAPICLQR---------------DPF--RRDM 103
            ::|||||..|:.|.||:||.....|:..|.|.:.||:|.|.               |..  ....
Zfish    74 YLGVPYATAPIGDRRFQPPEAPGSWQEVRNATQFAPVCPQNVHGVLPEIMLPVWFTDSLDVAATY 138

  Fly   104 ILEGSEDCLYLNVYTP---------------ERPRTNG-----SLPVMVWFHGGGWQCGSG---- 144
            |...||||||||||.|               .|||...     ..|||::.|||.:..|:|
Zfish   139 IQNQSEDCLYLNVYVPTEDGPLTKKHDESTLNRPRDEDIRDRRKKPVMLFIHGGSYMEGTGNMFD 203

  Fly   145 --ISSFYGPDFLLDHDIVLVSANFRLGPLGFLSTETLDCPGNNGLKDQLEVLHWVRANIASFGGD 207
              :.:.||       ::::|:.|:|||.||||||......||.||.||::.|.|:..||..||||
Zfish   204 ASVLAAYG-------NVIVVTMNYRLGVLGFLSTGDQSAKGNYGLLDQIQALRWLNENIGHFGGD 261

  Fly   208 PNSVTVFGESAGGASVTYHMLSEKSRGLLHRGIAQSGTYFNPWA---QPAHKGVAAGRATK-LAQ 268
            |..:|:||..||.:.|...:||..|.||..|.|||||:..:.|:   ||.       :.|| ||:
Zfish   262 PERITIFGSGAGASCVNLLILSHHSEGLFQRAIAQSGSAISSWSISYQPL-------KYTKILAR 319

  Fly   269 IVGCGNAGEWPEKLECLRKKPAEDIVASLYDMFVWDFDPM---IPFPPVV-------EPE---HD 320
            .||| ..||..:.::|||:|...::|..       |..|.   |.|.||:       :||   ..
Zfish   320 KVGC-TYGETADLVDCLRRKNFRELVDQ-------DIQPARYHIAFGPVMDGDVVPDDPEILMQQ 376

  Fly   321 GAFLT----VAPRQAAKPHGLQLPLMVGATAEEGLLKTAALLNLPQLLAEFKSQFEQVLPVVLNY 381
            |.||.    :...|.   .||:.....|..:|||:...|           |.......:..:..|
Zfish   377 GEFLNYDLLIGVNQG---EGLKFVDDGGTESEEGISAAA-----------FDYTISNFVDNLYGY 427

  Fly   382 DHHDDSVRQTITQRIESFYFKSGHDYD--KANHQNLTDLISDGWFVAGIDEYLRLRMSQEDVAPT 444
            ....|.:|:||     .|.:....|.|  :...:.|..|.:|..:||......:|....:  :|.
Zfish   428 PKGKDILRETI-----KFMYTDWADRDNGEMRRKTLLALFTDHQWVAPAIATAKLHADYQ--SPV 485

  Fly   445 YVYLFDHKGAASFTEIFKGGRNEFYGACHAEELQYLFPI----GRELFVSAVP---TQKDLELRE 502
            |.|.|.|.   ..||.    |.|:..|.|.:|:.|:|.:    ..:||    |   ::.|:.|..
Zfish   486 YFYTFYHH---CQTET----RPEWADAAHGDEIPYVFGVPMIGATDLF----PCNFSKNDIMLSA 539

  Fly   503 LMLHLWVSFAKTGNPN---PTNVSF-HL-PN------WSPASSYPVEFARLGTKMEDSASIFRLE 556
            :::..|.:|||||:||   |.:..| |. ||      |:..:|...::..:|.|.       |:.
Zfish   540 VVMTYWTNFAKTGDPNLPVPQDTKFIHTKPNRFEEVIWTKFNSKDKQYLHIGLKP-------RIR 597

  Fly   557 NELMQHRVDFWRDLQPHLPASHAHNEL 583
            :....::|.||.:|.|||  .:.|.|:
Zfish   598 DNYRANKVAFWLELVPHL--HNLHEEV 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_570089.1	COesterase	28..567	CDD:395084	176/594 (30%)
nlgn2a	XP_009301340.1	COesterase	47..608	CDD:395084	176/594 (30%)