Protein Alignment CG6414 and Ces2h

DIOPT Version :9

• Sequence 1: NP_001303565.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_001258974.1
• Gene: Ces2h / 436059
• MGIID: 3648740
• Length: 558
• Species: Mus musculus
• Alignment Length: 615
• Identity: 172/615 - (27%)
• Similarity: 260/615 - (42%)
• Gaps: 144/615 - (23%)

  Fly    13 ILLCICIQWSDGRNSQCLHVRLSHGGWLIGRHLTTHNGRHMR-------AFMGVPYAEPPLDDLR 70
            :||.:.:|..|..:.    :|.:|.|.::|..:      ||:       :|:|:|:|:||:..||
Mouse    17 LLLLLRVQGQDSTSP----IRTTHTGQILGSLI------HMKDLDVGVHSFLGIPFAKPPVGPLR 71

  Fly    71 FRPPVPKAPWEGERLAIKDAPICLQ----------------RDPFRRDMILEGSEDCLYLNVYTP 119
            |.||.|..||.|.|.......:|||                ..||..      ||||||||:|.|
Mouse    72 FAPPEPPEPWGGVRDGTSHPAMCLQDITAMNMQAFKLLKLTLPPFPM------SEDCLYLNIYAP 130

  Fly   120 ERPRTNGSLPVMVWFHGGGWQCGSGISSFYGPDFLLD-HDIVLVSANFRLGPLGFLSTETLDCPG 183
            :......:||||||.|||....  |::|.|....|.. .::|:|:..:|||.|||.||......|
Mouse   131 DHAHEGSNLPVMVWIHGGSLVI--GMASMYDGSMLAAMENVVVVTIQYRLGVLGFFSTGDERARG 193

  Fly   184 NNGLKDQLEVLHWVRANIASFGGDPNSVTVFGESAGGASVTYHMLSEKSRGLLHRGIAQSG---- 244
            |.|..||:..|.|::.|||.|||:|:.||:||.||||.||:..::|..|:||....|.:||
Mouse   194 NWGYLDQVAALRWLQQNIAYFGGNPDRVTIFGTSAGGTSVSSLVVSPMSQGLFRGAIMESGVALI 258

  Fly   245 -TYFNPWAQPAHKGVAAGRATKLAQIVGCGNAGEWPEKL-ECLRKKPAEDIVASLYDMFVWDFDP 307
             :..:..:...::.|        |.:.||.....  |.| .|||.|..|:|:|......:
Mouse   259 SSLISVSSDVVYQTV--------ANLSGCEQVDS--EALVNCLRGKSEEEIMAINKAFKI----- 308

  Fly   308 MIPFPPVVEPEHDGAFLTVAPRQAAKPHGLQLPLMVGATAEEGLLKTAALLNLPQLLAEFKSQFE 372
               .|.:|    ||.||...|::                    |:.:|....:|.::.....::.
Mouse   309 ---IPGIV----DGIFLPRHPQE--------------------LMASADFHPVPSIIGVNNDEYG 346

  Fly   373 QVLP----VVLNYDHHDDSVRQTITQR---------------IESFYFKSGHDYDKANHQ-NLTD 417
            .::|    ::.:....|..:.|.|.||               :|.:   .|.:.|....| ...:
Mouse   347 WIIPSSMSMIDSKKGMDRQMVQAILQRRATQMMWPPEVSDLLMEEY---MGDNEDPQFLQVQFKE 408

  Fly   418 LISDGWFVAGIDEYLRLRMSQEDVAPTYVYLFDHKGAASFTEIFKGGRNEFYGACHAEELQYLFP 482
            ::.|..||.   ..|::...|...||.:.|.|.|:  .||   ||..:.....|.|.:|:.::|
Mouse   409 MMKDFTFVI---PALQVAQFQRSHAPVFFYEFQHR--PSF---FKDSKPSHVKADHGDEILFIF- 464

  Fly   483 IGRELFVSAVPTQKDL-ELREL----MLHLWVSFAKTGNPNPTNVSFHLPNWSPASSYPVEFARL 542
              |..:..   ||.|. |..||    |:..|.:||:..|||    |..||.| |......::.:|
Mouse   465 --RSFWGG---TQVDFTEEEELLSRRMMKYWANFARQRNPN----SEGLPYW-PMFDQDEQYLQL 519

  Fly   543 GTKMEDSASIFRLENELMQHRVDFWRDLQP 572
            .|:.       .:...|...|:.||....|
Mouse   520 DTQP-------AVGRALKTRRLQFWTKTLP 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_001303565.1	COesterase	36..567	CDD:278561	164/585 (28%)
		Aes	<116..>254	CDD:223730	56/143 (39%)
Ces2h	NP_001258974.1	COesterase	30..537	CDD:278561	165/595 (28%)
		Aes	<127..>230	CDD:223730	45/104 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.810