Protein Alignment CG6414 and Nlg4

DIOPT Version :10

• Sequence 1: NP_570089.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Alignment Length: 737
• Identity: 195/737 - (26%)
• Similarity: 292/737 - (39%)
• Gaps: 212/737 - (28%)

  Fly     1 MSKDAGLWSIRVILL-CICIQWSD--GRNSQCLH--VRLSHG------GWLIGRHLTTHNGRHMR 54
            |.:...|..:|::|| .:.|.|..  |.::..::  .||.|.      |.|.|..|...:.|.:|
  Fly     1 MGESQLLLLLRLLLLPTVLISWMHCAGASTADIYKGARLGHRIVQTRYGRLHGLILPLDSFRFLR 65

  Fly    55 A---FMGVPYAEPPLDDLRFRPPVPKAPWEGERLAIKDAPICLQRDP------------------ 98
            :   |:|||||.||....||.|....|||:|.|::.|.:|:|.||.|
  Fly    66 SVEVFLGVPYATPPTKQNRFSPTRAPAPWDGIRISDKYSPVCPQRLPNIQNETAALEKMPKGRLE 130

  Fly    99 -FRRDM-ILEG-SEDCLYLNVYTPERPRTN-GSLPVMVWFHGGGWQCGSG------ISSFYGPDF 153
             .:|.: .||. |||||||||::|.....| ..|||:|:.||..::..||      :.:.||
  Fly   131 YLKRLLPFLENQSEDCLYLNVFSPVNAGANEKKLPVIVFIHGESFEWSSGNPYDGSVLASYG--- 192

  Fly   154 LLDHDIVLVSANFRLGPLGFLSTETLDCP--------GNNGLKDQLEVLHWVRANIASFGGDPNS 210
                ::|:|:.|:|||.||||:..    |        .|.||.||:..|||::.||..|||||||
  Fly   193 ----EVVVVTLNYRLGILGFLNAN----PNPHAHARVANYGLMDQMAALHWIQQNIQKFGGDPNS 249

  Fly   211 VTVFGESAGGASVTYHMLSEKS-RGLLHRGIAQSGTYFNPWAQPAHKGVAAGRATKLAQIVGC-- 272
            ||:.|...|.|.:.|.|.|... |||.||.|..||:.::.||......:.   |.|||:.|.|
  Fly   250 VTLAGHGTGAACINYLMTSPTMVRGLFHRAILMSGSAYSSWALVEDPVLF---AIKLAKEVNCTI 311

  Fly   273 -GNAGEWPEKL-ECLRKKPAEDIVASLYDM----FVWDFDPMIPFPPVVEPEHDGA----FLTVA 327
             .:.....|:: :|||..|.||:.  |.|:    |:..|.|.:. ..|:.|.|...    .:...
  Fly   312 PDDINRHHEQIVDCLRDVPLEDLY--LADIQAPNFLTSFGPSVD-GVVIRPGHSNLDIDDLMARN 373

  Fly   328 PRQAAKPHGLQ-------------------------------------------LPLMVGATAEE 349
            .|:::...|.|                                           ..::.|....|
  Fly   374 SRRSSADSGFQSSAGGGGGQGGGAGGGGGGGSGSSFGGGYFGGSGAGTMNMGGHYDVLFGVVTGE 438

  Fly   350 GLLKTAALLNLPQLLAEFKSQFEQ------VLPVVLN-YDHHDDSVRQTITQRIESFYFKSGHDY 407
            .:.:.:|        .:.::.||.      :...|.| |::|.:.:..||.....        |:
  Fly   439 SIWRFSA--------HDIQNGFEGERRDKIIRTYVRNAYNYHLNEIFYTIVNEYT--------DW 487

  Fly   408 DKANHQ--NLTD----LISDGWFVAGI---DEYLRLR----MSQEDVAPT--------------- 444
            |:.:..  |..|    .:||..|||.|   .:.|...    :|....|.:
  Fly   488 DRTSQHPINTRDTAVAALSDAQFVAPIVRAGDILAANSPPPVSSSSTAGSPGANAAASTSAGSTQ 552

  Fly   445 -----YVYLFDHKGAASFTEIFKGGRNEFYGACHAEELQYLFPIGRELF--VSAVP---TQKDLE 499
                 |.|:||:       :...|...:..|..|.|:|.|:|  |..|.  .|..|   |:.:..
  Fly   553 PSGRCYFYVFDY-------QTKDGDYPQRMGTVHGEDLPYIF--GAPLVDGFSHFPQNYTKSETA 608

  Fly   500 LRELMLHLWVSFAKTGNPN---------PTNVS---FHLPNWSPASSYPVEFARLGTKMEDSASI 552
            |.|.::..|.:||:|||||         |.:..   |....|........::..:|.|.
  Fly   609 LSEAVMIFWTNFARTGNPNEHHRQDSSLPVSKERNRFRSITWENYDPLHQKYLEIGMKP------ 667

  Fly   553 FRLENELMQHRVDFWRDLQPHL 574
             |::|....|::..|..|.|.|
  Fly   668 -RIKNHFRAHQLSIWLRLIPEL 688

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_570089.1	COesterase	28..567	CDD:395084	183/698 (26%)
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	180/686 (26%)