Protein Alignment CG6414 and Nlg3

DIOPT Version :10

• Sequence 1: NP_570089.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: XP_061500330.1
• Gene: Nlg3 / 3290865
• VectorBaseID: AGAMI1_000316
• Length: 952
• Species: Anopheles gambiae
• Alignment Length: 667
• Identity: 185/667 - (27%)
• Similarity: 285/667 - (42%)
• Gaps: 165/667 - (24%)

  Fly    26 NSQCLHVRLSHGGWLIG--RHLTTHNGRHM---RAFMGVPYAEPPLDDLRFRPPVPKAPWEGERL 85
            :|:.:|.:.   |.:.|  .||   :|||:   .||.|||||.||:.:|||.|||..|.|.|.:.
Mosquito    62 SSRIVHTKY---GAVSGTIEHL---DGRHLDPVEAFRGVPYASPPVGNLRFMPPVTGALWSGVKK 120

  Fly    86 AIKDAPICLQR--DPFRRDMILE-------------------GSEDCLYLNVYTPERPRTNGS-- 127
            |.:.:|:|.||  |.:.....||                   .||||||||:|.|.:..:..|
Mosquito   121 ADRFSPVCPQRLPDIYNETAALERMPRGRLEYLRRLLPYLRNQSEDCLYLNIYVPTQAGSRESSS 185

  Fly   128 ---LPVMVWFHGGGWQCGSG------ISSFYGPDFLLDHDIVLVSANFRLGPLGFLSTET---LD 180
               ..|:|:.||..::..||      :.:.||       .|::|:.|:|||.||||:...   ..
Mosquito   186 TSKYAVVVFVHGESYEWNSGNPYDGSVLASYG-------QILVVTINYRLGILGFLNANVDRFSK 243

  Fly   181 CPGNNGLKDQLEVLHWVRANIASFGGDPNSVTVFGESAGGASVTYHMLSEK-SRGLL-HRGIAQS 243
            .|.|.||.|.:..|||::.||.:|||||.|||:.|...|.|.|.:.:.|.. ..||| ||.|..|
Mosquito   244 APANYGLMDIIAALHWIQENIEAFGGDPKSVTLAGHGTGAACVHFLIASAAVPEGLLFHRAIMMS 308

  Fly   244 GTYFNPWAQPAHKGVAAGRATKLAQIVGCGNAGEWPEK--LECLRKKPAEDIVASLYDMFVWDFD 306
            |:...||:.   .|..|..|..::..|.|  :.:.|.:  |:|||.||.|||:::  .:...||.
Mosquito   309 GSGLAPWSL---VGEPAKFAAYVSHHVNC--SPDLPHQLLLKCLRDKPLEDILST--SVRAPDFG 366

  Fly   307 PMIPFPPVVE---------PEHDGAFLT------VAPRQAAKPHGL------------------Q 338
            .  .|.|.|:         .:.||...:      .|.:.:|..|..                  :
Mosquito   367 N--AFGPSVDGVVIDTGEIQQMDGTHYSDYSGNPAATKPSAHIHNTLNTINAILLRKLAINKLSK 429

  Fly   339 LPLMVGATAEEGLL--------------KTAALLNLPQLLAEFKSQFEQVLPVVLN-YDHHDDSV 388
            ..|:||.|..|...              :.|.:|. ..:.:.:.....::|..::| |...:..|
Mosquito   430 YDLLVGVTRAEAYFAFNSEDVQYGIEADRRAKILK-NYVRSTYSFHLNEILATIVNEYTDWERPV 493

  Fly   389 RQTITQRIESFYFKSGHDYDKANHQNLTDLISDGWFVAGIDEYLRLRMSQEDVAPTYVYLFDHKG 453
            :..|..|.|:.                 :.:||...||...:...|..:  |...:::|:||::
Mosquito   494 QHPINIRDETL-----------------EALSDARIVAPAVQTADLHSA--DHRNSFLYVFDYQ- 538

  Fly   454 AASFTEIFKGGRNEFYGACHAEELQYLFP---IGRELFVSAVPTQKDLELRELMLHLWVSFAKTG 515
                |:.  |...:..|..|.|:|.|||.   :|.....:...|:.::.|.|.::..|.:|.:||
Mosquito   539 ----TKF--GDFPQRQGCIHGEDLPYLFGAPLVGGFNHFTRNYTKSEIALSEAVMIYWSNFIRTG 597

  Fly   516 NPNPTNVSFHLPN--------WSPASSYPVEFARLGTKMEDSASIFRLENELMQHRVDFWRDLQP 572
            |||....:.|:.:        |:|..|...::..|.||.       :|:|....||:.||.:|.|
Mosquito   598 NPNEQLENDHVRDRTRFKNIEWTPYESVHKKYLNLDTKP-------KLKNHYRAHRLSFWLNLVP 655

  Fly   573 --HLPAS----HAHNEL 583
              |.|.:    ..|:||
Mosquito   656 DLHKPGNDDVPSGHHEL 672

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_570089.1	COesterase	28..567	CDD:395084	175/641 (27%)
Nlg3	XP_061500330.1	None