Protein Alignment CG6414 and Ces4a

DIOPT Version :10

• Sequence 1: NP_570089.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_001099646.1
• Gene: Ces4a / 291955
• RGDID: 1307418
• Length: 563
• Species: Rattus norvegicus
• Alignment Length: 645
• Identity: 196/645 - (30%)
• Similarity: 287/645 - (44%)
• Gaps: 157/645 - (24%)

  Fly     4 DAGLWSIRVIL-----LCICIQWSDGRNSQCLHVR----LSHGGWLIGRHLTTHNG-RHMRAFMG 58
            :|| ||::..|     |.:.:|.:.|    .||.:    ::..|.|.|:.:  |.| ..:|.|:|
  Rat     3 EAG-WSMKWTLDLSLTLWLVVQTALG----ALHTKEPLLITKHGILQGKQV--HVGDTPIRVFLG 60

  Fly    59 VPYAEPPLDDLRFRPPVPKAPWEGERLAIKDAPICLQR----------DPFRRDMILEGSEDCLY 113
            ||:::||:...||.||.|..||.|.|.|....|.|||.          :..::...|..||||||
  Rat    61 VPFSQPPVGTRRFAPPEPPLPWNGIRDATTYPPSCLQESWGQITSMYLNTRKQYEWLHFSEDCLY 125

  Fly   114 LNVYTPERPRTNGSLPVMVWFHGGGWQCGSGISSFYGPDFLLDHDIVLVSANFRLGPLGFLSTET 178
            ||||.|.....:..|||||||.||.:..||. |::.|.:......:|||...:|||.|||.||..
  Rat   126 LNVYAPVLAPGDPLLPVMVWFPGGAFLVGSA-STYEGSELAARGKVVLVFLQYRLGILGFFSTGN 189

  Fly   179 LDCPGNNGLKDQLEVLHWVRANIASFGGDPNSVTVFGESAGGASVTYHMLSEKSRGLLHRGIAQS 243
            ....||.||.||:..|.||:.||.:|||||:|||:||:|||..||:..::|..::||.|:.|:||
  Rat   190 SHARGNWGLLDQIAALRWVQENIEAFGGDPDSVTLFGQSAGAMSVSGLLMSPLAQGLFHQAISQS 254

  Fly   244 GT-------YFNPWAQPAHKGVAAGRATKLAQIVGCGNAGEWPEKLECLRKKPAEDIVASLYDM- 300
            ||       ..:|...          |.|:|.:.||.: ......::||:..|||.::.....|
  Rat   255 GTAVLKTFITHDPLKS----------AKKIAHLAGCDH-NSTKIMVKCLKALPAEKVMLVSKKMT 308

  Fly   301 ------------FVWDFDPMIPFPPVVEPEHDGAFLTVAPRQAAKPHGLQLPLMVGATAEEG--- 350
                        .||...|::  ..:|.||.....||   |...||    :|.::|..:.|.
  Rat   309 FFRANSHKDPKDIVWFLSPVV--DGLVFPEDPVVLLT---RGQVKP----VPYLLGVNSAEFEWS 364

  Fly   351 ----------------------LLKTAALLNLPQLLAEFKSQFEQVLPVVLNYDHHDDSVRQTIT 393
                                  |...:.|||:.          |:.:|:|         .|:.::
  Rat   365 LPFLMKLQLNQRIMNKNYITKLLWSCSILLNIT----------EEQIPLV---------AREYLS 410

  Fly   394 QRIESFYFKSGHDYDKANHQNLTDLISDGWFVAGIDEYLRL---RMSQEDVAPTYVYLFDHKGAA 455
            ..|      |.||: |....:|.||:.|..||     |..|   |..::..:|.|:|.|.|....
  Rat   411 DAI------SHHDW-KMFRNHLIDLVGDATFV-----YATLQAARYHRDAGSPVYLYEFKHHAPG 463

  Fly   456 SFTEIFKGGRNEFYGACHAEELQYLF--PIGRELFVSAVPTQKDLELRELMLHLWVSFAKTGNPN 518
                |....|::  ||.|.:||.|||  |..:.   |:...:|:..|:  |:..|.:||.||:||
  Rat   464 ----IIVKPRSD--GADHGDELSYLFGSPFSKG---SSRGEEKEFSLQ--MMKYWANFAHTGDPN 517

  Fly   519 PTNVSFHLPNWSPASSY-PVEF-ARLGTKMEDSASIFRLENELMQHRVDFWRDL-QPHLP 575
            ...:.: .|.:.....| .::| .|:|.|             |.:.::.|||.| ||..|
  Rat   518 DRELPY-WPRFDKEEKYLQLDFDTRVGVK-------------LREKQMTFWRRLRQPQKP 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_570089.1	COesterase	28..567	CDD:395084	181/605 (30%)
Ces4a	NP_001099646.1	COesterase	33..554	CDD:395084	179/599 (30%)