Protein Alignment CG6414 and cest-9.2

DIOPT Version :10

• Sequence 1: NP_570089.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_741910.3
• Gene: cest-9.2 / 259729
• WormBaseID: WBGene00007695
• Length: 617
• Species: Caenorhabditis elegans
• Alignment Length: 647
• Identity: 148/647 - (22%)
• Similarity: 236/647 - (36%)
• Gaps: 218/647 - (33%)

  Fly    20 QWSDGRNSQCLHVRLSHGGWLIGRHLTTHNGRHMRAFMGVPYAEPPLDDLRFRPPVPKAPWEGER 84
            :|||..|                         |...|..||:|:||:..|||.||.....|.|..
 Worm    36 EWSDDNN-------------------------HKYMFKSVPFAKPPIGKLRFAPPQYPDSWSGVL 75

  Fly    85 LAIKDAPICLQRDPFRRDMILEGSEDCLYLNVYTPERPRTNGSLPVMVWFHGGGWQCGSGISSFY 149
            .|.|.:|.||.............||||||:|::|.|: .......|:|:||||.:   :|.|:..
 Worm    76 DASKYSPACLSNSSTTSTPQEHVSEDCLYINIFTSEK-CLRSKCAVIVYFHGGAY---NGDSATM 136

  Fly   150 GPD-FLLD----HDIVLVSANFRLGPLG-------FLSTETLDCPGNNGLKDQLEVLHWVRANIA 202
            .|| |:|:    .|::|.....|||..|       .|.||.|      .:.|.::.|.:|...|.
 Worm   137 FPDNFILERYVAEDVILAIPGVRLGVFGQLYFGPSALLTENL------FMFDAVQALDFVHNEIP 195

  Fly   203 SFGGDPNSVTVFGESAGGASVT---YHMLSEKSRGLLHRGIAQSGT----YFNPWAQPAHKGVAA 260
            :|||||..||:.|.|:||..|.   :....:....|..:.|..|||    :::         :..
 Worm   196 NFGGDPKQVTIMGHSSGGTLVEALGFSNSVDPDLKLFQQIIVLSGTGMFGFYD---------LLV 251

  Fly   261 GRATKLAQIVGCGNAGEWPEK--------LECLRKKPAEDIVA---SLYDMFVWDFDPMIPFPPV 314
            ..:..:::.:||.| |...|:        |||:|:....:||.   .:.|::...|..::...|.
 Worm   252 DNSFIISEKLGCFN-GTQEERTDANIAEILECMRQIDGHEIVGMQKHMEDVYKLTFKSLLRGAPF 315

  Fly   315 VEPEHDGAF----LTVAPRQAAKPHGLQLPLMVGATAEEGLLKTAALLNLPQLLAEFKSQFEQVL 375
            :  |.:|..    .:.:||.|           :..|.|                .||:::.|:.|
 Worm   316 M--ELNGKIEKFRNSTSPRNA-----------IFGTTE----------------YEFRNEVERYL 351

  Fly   376 PVVLNY----------DHHDDSVRQTITQRIESFYFKSGHDYDKANHQNLTDLISDGWFV----- 425
            .:...:          .|.||.:.|.:...|              |...::..:|...|.
 Worm   352 YITTTFLDFENPVAVAQHFDDELMQNMDTMI--------------NGDAVSIFVSAAAFSSAMAN 402

  Fly   426 AGIDEYLRLRMSQEDVAPTYVYLFDHKGAASFTEIFKGGRNEFYGACHAEELQYLFPIGRELFVS 490
            ||.|                ||||:.:              ::..:.|..::||...|.||:..:
 Worm   403 AGAD----------------VYLFETR--------------QWPYSFHVSDMQYFIGIHREVLHT 437

  Fly   491 AVPTQKDLE-LRELMLHLWVSFAKTGNPNP---------------------------------TN 521
                 .|:: |......|.|:|.|||.|:|                                 ..
 Worm   438 -----HDMDILDSFYSKLLVNFTKTGAPSPEWNSLEPEKMNYLELRVDTRNGKGPVMLEGYHDKE 497

  Fly   522 VSFHLPNWSPASSY--PVEFARLGTKMEDSASIFRLENELMQHRVDFWRDLQPHLPASHAHN 581
            |||    |     |  .:::.|..|||..|..:.| ||:.::.::.:|..:......:||:|
 Worm   498 VSF----W-----YGDMMDYDRNITKMRQSKGLPR-ENQGVESQLKYWSSIVEPRTTAHANN 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_570089.1	COesterase	28..567	CDD:395084	140/623 (22%)
cest-9.2	NP_741910.3	alpha/beta hydrolases	22..501	CDD:473884	134/591 (23%)