Protein Alignment CG6414 and Nlgn3

DIOPT Version :9

• Sequence 1: NP_001303565.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_766520.2
• Gene: Nlgn3 / 245537
• MGIID: 2444609
• Length: 825
• Species: Mus musculus
• Alignment Length: 639
• Identity: 181/639 - (28%)
• Similarity: 267/639 - (41%)
• Gaps: 172/639 - (26%)

  Fly    45 LTTHNGRHMRA--------------FMGVPYAEPPLDDLRFRPPVPKAPWEGERLAIKDAPICLQ 95
            :.||.|:...|              ::|||||.||:.:.||.||.|...|.|.|.|....|:|.|
Mouse    41 VNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQ 105

  Fly    96 RDP-----------FRRDM------ILEGSEDCLYLNVYTP----------------------ER 121
            ...           |..::      |.|.:|||||||||.|                      |.
Mouse   106 NIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVYVPTEDGSGAKKQGEDLADNDGDEDED 170

  Fly   122 PRTNGSLPVMVWFHGGGWQCGSG------ISSFYGPDFLLDHDIVLVSANFRLGPLGFLSTETLD 180
            .|.:|:.||||:.|||.:..|:|      :.:.||       ::::::.|:|:|.||||||....
Mouse   171 IRDSGAKPVMVYIHGGSYMEGTGNMIDGSVLASYG-------NVIVITLNYRVGVLGFLSTGDQA 228

  Fly   181 CPGNNGLKDQLEVLHWVRANIASFGGDPNSVTVFGESAGGASVTYHMLSEKSRGLLHRGIAQSGT 245
            ..||.||.||::.|.||..|||.|||||..:||||...|.:.|:...||..|.||..|.|.|||:
Mouse   229 AKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGS 293

  Fly   246 YFNPWA---QPAHKGVAAGRATKLAQIVGCGNAGEWPEKLECLRKKPAEDIVASLYDMFVWDFDP 307
            ..:.||   ||..      ..:.||..||| |..:..:.::|||:|.|:::|..       |..|
Mouse   294 ALSSWAVNYQPVK------YTSLLADKVGC-NVLDTVDMVDCLRQKSAKELVEQ-------DIQP 344

  Fly   308 M---IPFPPVV-------EPE---HDGAFLTVAPRQAAKPHGLQLPLMVGATAEEGLLKTAALLN 359
            .   :.|.||:       :||   ..|.|             |...:|:|....|||.....:::
Mouse   345 ARYHVAFGPVIDGDVIPDDPEILMEQGEF-------------LNYDIMLGVNQGEGLKFVEGVVD 396

  Fly   360 LPQLLA--EFKSQFEQVLPVVLNYDHHDDSVRQTITQRIESFYFKSGHDYD--KANHQNLTDLIS 420
            ....::  :|.......:..:..|....|::|:||     .|.:....|.|  :...:.|..|.:
Mouse   397 PEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETI-----KFMYTDWADRDNPETRRKTLVALFT 456

  Fly   421 DGWFV--AGIDEYLRLRMSQEDVAPTYVYLFDH------KGAASFTEIFKGGRNEFYGACHAEEL 477
            |..:|  :.:...|..|..    :|||.|.|.|      |.|.|             .|.|.:|:
Mouse   457 DHQWVEPSVVTADLHARYG----SPTYFYAFYHHCQSLMKPAWS-------------DAAHGDEV 504

  Fly   478 QYLFPI----GRELFVSAVP---TQKDLELRELMLHLWVSFAKTGNPN---PTNVSF-HLP---- 527
            .|:|.:    ..:||    |   ::.|:.|..:::..|.:|||||:||   |.:..| |..
Mouse   505 PYVFGVPMVGPTDLF----PCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRF 565

  Fly   528 ---NWSPASSYPVEFARLGTKMEDSASIFRLENELMQHRVDFWRDLQPHLPASH 578
               .||..:.....:..:|.|.       |:.:.....:|.||:.|.|||...|
Mouse   566 EEVAWSKYNPRDQLYLHIGLKP-------RVRDHYRATKVAFWKHLVPHLYNLH 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_001303565.1	COesterase	36..567	CDD:278561	174/626 (28%)
		Aes	<116..>254	CDD:223730	62/168 (37%)
Nlgn3	NP_766520.2	COesterase	39..601	CDD:365897	174/626 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	151..172		1/20 (5%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	622..668

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810