Protein Alignment CG6414 and Ces4a

DIOPT Version :9

• Sequence 1: NP_001303565.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_666325.2
• Gene: Ces4a / 234677
• MGIID: 2384581
• Length: 563
• Species: Mus musculus
• Alignment Length: 634
• Identity: 198/634 - (31%)
• Similarity: 286/634 - (45%)
• Gaps: 144/634 - (22%)

  Fly     4 DAGLWSIRVIL-----LCICIQWSDGRNSQCLHVR----LSHGGWLIGRHLTTHNG-RHMRAFMG 58
            :|| |:::.||     ||:.:|.:.|    .||.:    ::..|.|.|:.:  |.| ..::.|:|
Mouse     3 EAG-WNMKWILGLSLTLCLVVQTALG----ALHTKEPLLITKHGILQGKQV--HVGDTPIQVFLG 60

  Fly    59 VPYAEPPLDDLRFRPPVPKAPWEGERLAIKDAPICLQR----------DPFRRDMILEGSEDCLY 113
            :|:::||:...||.||.|..||.|.|.|....|.|||.          :..::...|..||||||
Mouse    61 IPFSKPPVGTRRFAPPEPPLPWNGIRDATTYPPSCLQESWGQILSMYLNTRKQYKWLHFSEDCLY 125

  Fly   114 LNVYTPERPRTNGSLPVMVWFHGGGWQCGSGISSFYGPDFLLDHDIVLVSANFRLGPLGFLSTET 178
            ||||.|........|||||||.||.:..||. |::.|.:......:|||...:|||.|||.||..
Mouse   126 LNVYAPVLAPGAPLLPVMVWFPGGAFLAGSA-STYEGSELAARGKVVLVFLQYRLGILGFFSTGN 189

  Fly   179 LDCPGNNGLKDQLEVLHWVRANIASFGGDPNSVTVFGESAGGASVTYHMLSEKSRGLLHRGIAQS 243
            ....||.||.||:..|.||:.||.:|||||:|||:||:|||..||:..|:|..::||.|:.|:||
Mouse   190 SHARGNWGLLDQIAALRWVQENIEAFGGDPDSVTLFGQSAGAMSVSGLMVSPLAQGLFHQAISQS 254

  Fly   244 GT-----YFNPWAQPAHKGVAAGRATKLAQIVGCGNAGEWPEKLECLRKKPAEDI--VASLYDMF 301
            ||     :..|  .|...      |.|:|.:.||.: ......:||||...||::  |:.....|
Mouse   255 GTAVLKAFITP--DPLTS------AKKIAHLAGCDH-NSTKVMVECLRSLSAEEVTLVSKRMSFF 310

  Fly   302 -----------VWDFDPMIPFPPVVEPEHDGAFLTVAPRQAAKPHGLQLPLMVGATAEEGLLKTA 355
                       ||...|::  ..||.||.....||   |...||
Mouse   311 QANSHKDPKEIVWFLSPVV--DGVVFPEDPVVLLT---RGQVKP--------------------- 349

  Fly   356 ALLNLPQLLAEFKSQFEQVLPVVLNYDHHDDSVRQT-ITQRIESF-----------------YFK 402
                :|.||....::||..||.::....:...:.|| |.:.:.||                 |..
Mouse   350 ----VPYLLGVNNAEFEWNLPFLMKIQLNQRMMNQTNINKILWSFNVLLNITKEQVPVVAREYLN 410

  Fly   403 ---SGHDYDKANHQNLTDLISDGWFVAGIDEYLRL---RMSQEDVAPTYVYLFDHKGAASFTEIF 461
               |.||: |.....|.|||.|..||     |..|   |..::..:|.|:|.|.|..::..  |.
Mouse   411 DAISNHDW-KMFRNRLIDLIGDATFV-----YATLQAARYHRDAGSPVYLYEFKHHASSGI--II 467

  Fly   462 KGGRNEFYGACHAEELQYLF--PIGRELFVSAVPTQKDLELRELMLHLWVSFAKTGNPNPTNVSF 524
            |    .:.||.|.:||.|||  |..:.   |:...:|:..|:  |:..|.:||.|||||...:.:
Mouse   468 K----PYNGADHGDELSYLFGSPFSKG---SSAGEEKEFSLQ--MMKYWANFAHTGNPNGEKLPY 523

  Fly   525 HLPNWSPASSY-PVEF-ARLGTKMEDSASIFRLENELMQHRVDFWRDLQ 571
             .|.:.....| .::| .|:|.|:::.             ::.||..|:
Mouse   524 -WPRFDKDEKYLQLDFDTRVGVKLKEK-------------KMAFWSQLR 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_001303565.1	COesterase	36..567	CDD:278561	184/587 (31%)
		Aes	<116..>254	CDD:223730	64/142 (45%)
Ces4a	NP_666325.2	COesterase	30..554	CDD:278561	185/596 (31%)
		Aes	<128..>272	CDD:223730	65/152 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.810