Protein Alignment CG6414 and Ces2b

DIOPT Version :9

• Sequence 1: NP_001303565.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_937814.1
• Gene: Ces2b / 234669
• MGIID: 2448547
• Length: 556
• Species: Mus musculus
• Alignment Length: 620
• Identity: 182/620 - (29%)
• Similarity: 272/620 - (43%)
• Gaps: 128/620 - (20%)

  Fly    12 VILLCICIQWSDGRNSQCLHVRLSHGGWLIGR--HL-TTHNGRHMRAFMGVPYAEPPLDDLRFRP 73
            ::||...:|..|  :.:...:|.:|.|.:.|.  |: .|..|.|  .|:|:|:|:||:..|||.|
Mouse    17 LLLLLGHVQGQD--SPEASPIRNTHTGQVRGSLVHVKDTKAGVH--TFLGIPFAKPPVGPLRFAP 77

  Fly    74 PVPKAPWEGERLAIKDAPICLQRDPFRRDMILE-----GSEDCLYLNVYTPERPRTNGSLPVMVW 133
            |....||.|.|.......:|||.....:::.|:     .||||||||:|||.......:||||||
Mouse    78 PEAPEPWSGVRDGTAHPAMCLQNLGVMKEIKLKLPPVSTSEDCLYLNIYTPAHAHEGSNLPVMVW 142

  Fly   134 FHGGGWQCGSGISSFYGPDFLLD-HDIVLVSANFRLGPLGFLSTETLDCPGNNGLKDQLEVLHWV 197
            .||||  ..:|::|.|....|.. .|:|:|:..:|||.|||.||......||.|..||:..|.|:
Mouse   143 IHGGG--LVAGMASMYDGSLLAAIEDLVVVTIQYRLGVLGFFSTGDQHARGNWGFLDQVAALRWI 205

  Fly   198 RANIASFGGDPNSVTVFGESAGGASVTYHMLSEKSRGLLHRGIAQSGTYFNPWAQPAHKGVAAGR 262
            :.|||.|||.|:.||:|||||||.||:.|::|..|:||.|..|.:||....|:.......:.
Mouse   206 QQNIAHFGGKPDRVTIFGESAGGTSVSSHVVSPMSKGLFHGAIMESGVALLPYLITDTSEMV--- 267

  Fly   263 ATKLAQIVGCGNAGEWPEKLECLRKKPAEDIVA--SLYDMFVWDFDPMIPFPPVVEPEHDGAFLT 325
            :|.:|::.|| .|.:....:.|||.|...:|:|  .|..|          .|.||    ||.|..
Mouse   268 STTVAKLSGC-EAMDSEALVRCLRGKSEAEILAINKLVQM----------IPAVV----DGEFFP 317

  Fly   326 VAPRQAAKPH----------------GLQLPLMVGA-------TAE--EGLLK-TAALLNLPQ-- 362
            ..|::.....                |..:|:::|:       |.|  :.:|| |.|.|.||.
Mouse   318 RHPKELLASEDFHPVPSIIGVNNDEFGWTIPVVMGSAQTIKEITRENLQAVLKNTTAQLMLPPEC 382

  Fly   363 ---LLAEFKSQFEQVLPVVLNYDHHDDSVRQTITQRIESFYFKSGHDYDKANHQNLTDLISDGWF 424
               |:.|:....|....:.:.:           |:.:|.|.|
Mouse   383 SDLLMEEYMGDTEDAQTLQIQF-----------TEMMEDFMF----------------------- 413

  Fly   425 VAGIDEYLRLRMSQEDVAPTYVYLFDHKGAASFTEIFKGGRNEFYGACHAEELQYLFPIGRELFV 489
               :...|::...|...|..|.|.|.|:.|:     .|..|.....|.||:|:.::|  |...:.
Mouse   414 ---VIPALQVAYFQRSHASVYFYEFQHQIAS-----LKDVRPTHVKADHADEIPFVF--GYFFWD 468

  Fly   490 SAVP-TQKDLELRELMLHLWVSFAKTGNPNPTNVSFHLPNWSPASSYPVEFARLGTKMEDSASIF 553
            ..:. |:.:..|...|:..|.:||:.||||    |..||.| |...:..::.:|.|:.
Mouse   469 MKLDFTEGEKLLSRRMMKYWANFARHGNPN----SEGLPYW-PVMDHDEQYLQLDTQP------- 521

  Fly   554 RLENELMQHRVDFW-----RDLQPHLPASHAHNEL 583
            .:...|...|:.||     :.:|....:...|.||
Mouse   522 AVGRALKSRRLQFWTKTLSQKIQELRASQDKHTEL 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_001303565.1	COesterase	36..567	CDD:278561	171/573 (30%)
		Aes	<116..>254	CDD:223730	63/138 (46%)
Ces2b	NP_937814.1	COesterase	34..535	CDD:365897	172/578 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.810