Protein Alignment CG6414 and Ces1f

DIOPT Version :9

• Sequence 1: NP_001303565.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_659179.1
• Gene: Ces1f / 234564
• MGIID: 2142687
• Length: 561
• Species: Mus musculus
• Alignment Length: 630
• Identity: 197/630 - (31%)
• Similarity: 283/630 - (44%)
• Gaps: 129/630 - (20%)

  Fly     7 LWSIRVILLCICIQWSDGRNSQCLHVRLSHGGWLIGRHLTTHN-GRHMRAFMGVPYAEPPLDDLR 70
            |.|:...::|       |..|....|..:||. ::|:|:.... .:.:..|:|:|:|:|||..||
Mouse     8 LVSLATCVIC-------GNPSSPPVVDTAHGK-VLGKHVNVEGFSQPVAVFLGIPFAKPPLGSLR 64

  Fly    71 FRPPVPKAPWEGERLAIKDAPICLQ---RDPFRRDMI--------LEGSEDCLYLNVYTPERPRT 124
            |.||.|..||...:.|....|:|.|   |.....|:|        ||.||||||||:|||.....
Mouse    65 FAPPQPAEPWSSVKNATTYPPMCSQDAARGQAVNDLITNRKEKIHLEFSEDCLYLNIYTPADFSK 129

  Fly   125 NGSLPVMVWFHGGGWQCGSGISSFYGPDFLLDHDIVLVSANFRLGPLGFLSTETLDCPGNNGLKD 189
            |..||||||.||||.:.| |.|||.|.......::|:|:..:||...||.||......||.|..|
Mouse   130 NSRLPVMVWIHGGGLKLG-GASSFDGRALSAYENVVVVAIQYRLSIWGFFSTGDEHSRGNWGHLD 193

  Fly   190 QLEVLHWVRANIASFGGDPNSVTVFGESAGGASVTYHMLSEKSRGLLHRGIAQSGTYFNPW---- 250
            |:..||||:.|||:|||||.|||:|||||||.||:..:||..|:.|.||.|::||..|.|.
Mouse   194 QVAALHWVQDNIANFGGDPGSVTIFGESAGGYSVSILILSPLSKNLFHRAISESGVAFIPGMFTK 258

  Fly   251 -AQPAHKGVA--AG-RATKLAQIVGCGNAGEWPEKLECLRK------------KPAEDIVASLYD 299
             .:|..:.:|  || :.|..|.||.|.......|.||.:.|            |.::..|.|:.|
Mouse   259 DVRPITEQIAVTAGCKTTTSAVIVHCMRQKTEEELLEIMHKLNLYKLSLQGDTKNSDQFVTSVLD 323

  Fly   300 MFVWDFDPMIPFPPVVEPEHDGAFLTVAPRQAAKPH---------GLQLPLMVG-ATAEEGLLKT 354
            ..|...||.       |...:..|.||       |:         |..||.|.| ..|:..|.|.
Mouse   324 GVVLPKDPK-------EILAEKNFNTV-------PYIVGINKQECGWLLPTMTGFLPADVKLDKK 374

  Fly   355 AALLNLPQLLAEFKSQF---EQVLPVVLNYDHHDDSVRQTITQRIESFYFKSGHDYDKANHQNLT 416
            .|:    .||.:|.|..   |.::||.:..                  |.|...|.|:. .:.:.
Mouse   375 KAI----ALLEQFASMTGIPEDIIPVAVEK------------------YTKGSDDPDQI-REGVL 416

  Fly   417 DLISDGWFVAGIDEYLRLRMSQEDVAPTYVYLFDHKGAASFTEIFKGGRNEFYGACHAEELQYLF 481
            |.:.|..|  |:...:..|..::..||||:|.:.:..:.|..:     |.:.....||:::..:|
Mouse   417 DAMGDVAF--GVPSVIVSRGHRDTGAPTYMYEYQYYPSFSSPQ-----RPKNVVGDHADDVYSVF 474

  Fly   482 --PIGRELFVSAVPTQKDLELRELMLHLWVSFAKTGNPNPTNVSFHLPNWSPASSYPVEFARLGT 544
              ||.||     ..:::::.|.::::..|.:||:.||||...    ||:| |.......:..:|.
Mouse   475 GAPILRE-----GASEEEINLSKMVMKFWANFARNGNPNGKG----LPHW-PKYDQKEGYLHIGG 529

  Fly   545 KMEDSASIFRLENELMQHRVDFW------RDLQPHLPASHAHNEL 583
            ..:.:       ..|.:..|.||      :..||:      ||||
Mouse   530 TTQQA-------QRLKEEEVTFWTQSLAKKQPQPY------HNEL 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_001303565.1	COesterase	36..567	CDD:278561	183/577 (32%)
		Aes	<116..>254	CDD:223730	68/142 (48%)
Ces1f	NP_659179.1	COesterase	24..545	CDD:278561	184/583 (32%)
		Aes	<121..>225	CDD:223730	54/104 (52%)
		Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138	558..561		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.810