Protein Alignment CG6414 and Nlgn1

DIOPT Version :9

• Sequence 1: NP_001303565.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: XP_006535478.1
• Gene: Nlgn1 / 192167
• MGIID: 2179435
• Length: 863
• Species: Mus musculus
• Alignment Length: 704
• Identity: 201/704 - (28%)
• Similarity: 292/704 - (41%)
• Gaps: 189/704 - (26%)

  Fly     7 LWSIRVILLCICIQWSDGRNSQCL--------HVRLSHGGWLIGRHLTTHNGRHMRA-------- 55
            :|  |.::.|:..:.|....:.||        || ||.....:...:||:.|: :|.
Mouse    12 VW--RAMMACVVHRGSGAPLTLCLLGCLLQTFHV-LSQKLDDVDPLVTTNFGK-IRGIKKELNNE 72

  Fly    56 -------FMGVPYAEPPLDDLRFRPPVPKAPWEGERLAIKDAPICLQ-----RDP-------FRR 101
                   |:|||||.||..:.||:||.|.:||...|.|.:.||:|.|     |.|       |..
Mouse    73 ILGPVIQFLGVPYAAPPTGEHRFQPPEPPSPWSDIRNATQFAPVCPQNIIDGRLPEVMLPVWFTN 137

  Fly   102 DM------ILEGSEDCLYLNVYTP------------ERP-----RTNGSL--------------- 128
            ::      :.:.||||||||:|.|            .:|     |..|.|
Mouse   138 NLDVVSSYVQDQSEDCLYLNIYVPTEDVKRISKECARKPGKKICRKGGPLTKKHTDDLGDNDGAE 202

  Fly   129 -----------PVMVWFHGGGWQCGSGISSFYGPDFLLDH-DIVLVSANFRLGPLGFLSTETLDC 181
                       ||||:.|||.:..|:|  :.|....|..: ::::::.|:|||.||||||.....
Mouse   203 DEDIRDSGGPKPVMVYIHGGSYMEGTG--NLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAA 265

  Fly   182 PGNNGLKDQLEVLHWVRANIASFGGDPNSVTVFGESAGGASVTYHMLSEKS---------RGLLH 237
            .||.||.|.::.|.|...||..|||||..:||||..|||:.|....||..|         :||..
Mouse   266 KGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQ 330

  Fly   238 RGIAQSGTYFNPWA---QPAHKGVAAGRATKLAQIVGCGNAGEWPEKLECLRKKPAEDIVASLYD 299
            |.||||||..:.||   |||.      .|..||..||| |..:..|.:|||:|||.:::|..
Mouse   331 RAIAQSGTALSSWAVSFQPAK------YARILATKVGC-NVSDTVELVECLQKKPYKELVDQ--- 385

  Fly   300 MFVWDFDPM---IPFPPVVEPEHDGAFLTVAPRQAAKPHG--LQLPLMVGATAEEGLLKTAALLN 359
                |..|.   |.|.||:    ||..:...| |.....|  |...:|:|....|||.....:::
Mouse   386 ----DVQPARYHIAFGPVI----DGDVIPDDP-QILMEQGEFLNYDIMLGVNQGEGLKFVENIVD 441

  Fly   360 LPQ--LLAEFKSQFEQVLPVVLNYDHHDDSVRQTITQRIESFYFKSGHD--YDKANHQNLTDLIS 420
            ...  ..::|.......:..:..|....|.:|:||     .|.:....|  ..:...:.|..|.:
Mouse   442 SDDGVSASDFDFAVSNFVDNLYGYPEGKDVLRETI-----KFMYTDWADRHNPETRRKTLLALFT 501

  Fly   421 DGWFVAGIDEYLRLRMSQEDV-----APTYVYLFDHKGAASFTEIFKGGRNEFYGACHAEELQYL 480
            |..:||.       .::..|:     :|||.|.|.|.........:.       .|.|.:|:.|:
Mouse   502 DHQWVAP-------AVATADLHSNFGSPTYFYAFYHHCQTDQVPAWA-------DAAHGDEVPYV 552

  Fly   481 FPI----GRELFVSAVP---TQKDLELRELMLHLWVSFAKTGNPN---PTNVSF-HL-PN----- 528
            ..|    ..|||    |   ::.|:.|..:::..|.:|||||:||   |.:..| |. ||
Mouse   553 LGIPMIGPTELF----PCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEV 613

  Fly   529 -WSPASSYPVEFARLGTKMEDSASIFRLENELMQHRVDFWRDLQPHLPASHAHN 581
             |:..|.....:..:|.|.       |::.....::|:.|.:|.|||     ||
Mouse   614 AWTRYSQKDQLYLHIGLKP-------RVKEHYRANKVNLWLELVPHL-----HN 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_001303565.1	COesterase	36..567	CDD:278561	184/651 (28%)
		Aes	<116..>254	CDD:223730	64/193 (33%)
Nlgn1	XP_006535478.1	COesterase	53..646	CDD:365897	184/644 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810