Protein Alignment CG6414 and cest-7

DIOPT Version :10

• Sequence 1: NP_570089.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_001257187.1
• Gene: cest-7 / 182819
• WormBaseID: WBGene00007693
• Length: 606
• Species: Caenorhabditis elegans
• Alignment Length: 559
• Identity: 137/559 - (24%)
• Similarity: 215/559 - (38%)
• Gaps: 124/559 - (22%)

  Fly    45 LTTHNGR------------HMRAFMGVPYAEPPLDDLRFRPPVPKAPWEGERLAIKDAPICLQRD 97
            |.|:.|:            |...|.|:|:|:|||..|||..|.....|.|.....|.:..||...
 Worm    40 LNTNYGKVRGITDFSDKRNHKYIFKGIPFAKPPLGLLRFALPEEPNTWNGVLDGSKYSAACLSNS 104

  Fly    98 PFRRDMILEGSEDCLYLNVYTPERPRTNGSLPVMVWFHGGGWQCGSGISSFYGPDFLL----DHD 158
            ..........||||||:|::|.|....: ..||:|::|||.:...|  ::.:...|:|    |..
 Worm   105 SLASAQQENISEDCLYINIFTSEYCLAH-KCPVLVYYHGGSFNLDS--ATMFPDKFILERYVDSG 166

  Fly   159 IVLVSANFRLGPLG-FLSTETLDCPGNNGLKDQLEVLHWVRANIASFGGDPNSVTVFGESAGGAS 222
            ||.....:|||..| |...|....|.|..:.|.:..|::|..||||||||||.||:.|.|:||..
 Worm   167 IVFAIPAYRLGVFGQFYLGEQGIVPANLLIHDCIRSLNFVHDNIASFGGDPNYVTLMGHSSGGQL 231

  Fly   223 VTYHMLS---EKSRGLLHRGIAQS--GTYFNPWAQPAHKGVAAGRATKLAQIVGCGNAGEWPEKL 282
            |.....|   :..:.|..:.|..|  |.|       ..:.:..|.:.::|:...|.:... .|.:
 Worm   232 VNAMGFSNQIDPEKKLFQQFIVLSSIGMY-------GFEDLQIGNSYEIARRHNCTSENS-QEIV 288

  Fly   283 ECLRKKPAEDIVAS---LYDMFVWDFDPMIPFPPVVEPEHDGAFLTVAPRQAAKPHGLQLPLMVG 344
            :|:|...|..::.:   :.|:.:..|..:|..||:::.:.        .....|.:.....::.|
 Worm   289 DCMRNIDALQLLQTQTVMDDVDLLFFKAIIRAPPLMDVKQ--------KLSEFKENVTARNMLCG 345

  Fly   345 ATAEE--------GLLKTAALL---NLPQLLAEFKSQFEQVLPVVLNYDHHDDSVRQTITQRIES 398
            .|..|        |...:|..|   |....:..::::|..:.|..:|.|              .|
 Worm   346 VTDNEFTIFKYPDGYYISATFLDFENPVDTVNVYRNKFTNITPTFVNSD--------------SS 396

  Fly   399 FYFKSGHDYDKANHQNLTDLISDGWFVAGIDEYLRLRMSQEDVAPTYVYLFDHKGAASFTEIFKG 463
            ..|.|...|.:|    ||:                        |...||||:.:
 Worm   397 AVFVSAATYSEA----LTN------------------------AGGNVYLFESR----------- 422

  Fly   464 GRNEFYGACHAEELQYLFPIGRELFVSAVPTQKDLELRELMLHLWVSFAKTGNPNPTNVSFHLPN 528
             :..|  :.|..::||...|.||   ....|..|: |......|.|:|.|.|:|:        ||
 Worm   423 -QKPF--SMHVTDMQYFIGIHRE---KNHTTDMDI-LDSFYSKLLVNFTKFGSPS--------PN 472

  Fly   529 WSPASSYPVEFARLGTKMEDSASIFRLENELMQHRVDFW 567
            |.......:.|..:....|..... ::||...:..|:||
 Worm   473 WEKYDPSKMNFMAMEIDTEQGIEP-KMENGFHEELVNFW 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_570089.1	COesterase	28..567	CDD:395084	135/557 (24%)
cest-7	NP_001257187.1	alpha/beta hydrolases	38..510	CDD:473884	135/557 (24%)