Protein Alignment CG6414 and cest-3

DIOPT Version :10

• Sequence 1: NP_570089.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_510042.2
• Gene: cest-3 / 181385
• WormBaseID: WBGene00008451
• Length: 588
• Species: Caenorhabditis elegans
• Alignment Length: 554
• Identity: 133/554 - (24%)
• Similarity: 222/554 - (40%)
• Gaps: 110/554 - (19%)

  Fly    38 GWLIGRHLTTHNGRHMRAFMGVPYAEPPLDDLRFRPPVPKAPWEGERLAIKDAPICLQRDPFRRD 102
            |.|.|:  |.:..:||  |..||:|:|||..|||..|....||:..|.|.:.:|.|......|.|
 Worm    29 GKLEGK--TVNVDQHM--FKNVPFAKPPLGKLRFSLPEWTNPWKNIRNATEYSPSCFSNSSMRTD 89

  Fly   103 M-ILEGSEDCLYLNVYTPERPRTNGSLPVMVWFHGGGWQCGSGISSFYGPDFLLD----HDIVLV 162
            . ....|||||||||:|.|....:.:...:|::||||....|.:.  :...|:|:    .::|.:
 Worm    90 SNFFPMSEDCLYLNVFTNEYCLKSKNCSTVVYYHGGGINMDSAVQ--FNDTFILERYVKENVVFI 152

  Fly   163 SANFRLGPLGFL--STETLDCPGNNGLKDQLEVLHWVRANIASFGGDPNSVTVFGESAGG-ASVT 224
            ...:|||..|.|  .:..| .|.|..:.|....|.::...|::|||..:.:.:.|.|||. .|:.
 Worm   153 IPAYRLGIFGLLYFGSNNL-VPQNLAIHDCELALRFIHQEISNFGGHKDDINLMGHSAGAHISLI 216

  Fly   225 Y----HMLSEKSRGLLHRGIAQS--GTYFNPWAQPAHKGVAAGRATKLAQIVGC---GNAGEWPE 280
            :    |:  :....|::|.|..|  .:|..|       .:........|:.|||   .......|
 Worm   217 FGFSRHI--DPDHKLINRIIVLSPVPSYDMP-------ELLIKNCYDFAERVGCYKRNVTARDTE 272

  Fly   281 KLECLRKKPAEDIVA--SLYD---MFVWDFDPMIPFPPVVEPEHDGAFLTVAPRQAAKPHGLQLP 340
            .::|||||.|..:::  .|.:   ::.|:|....||  :...|....|         |.:.::..
 Worm   273 IVKCLRKKDARGLMSMQRLMENDRLYFWNFLAGEPF--MYRDESIADF---------KEYAVKRD 326

  Fly   341 LMVGATAEEGLLKTAALLNLPQLLAEFKSQFEQVLPVVLNYDHHDDSVRQTITQRIESFYFKSGH 405
            :::|.|.:|...|.....| |.:...| ..:|....|...::.:.||.  .:....|||
 Worm   327 MLIGNTVDEVKWKRLKKEN-PAIAGSF-MDWENPYEVAHKFNFYHDSA--PVNSTYESF------ 381

  Fly   406 DYDKANHQNLTDLISDGWFVAGIDEYLRLRMSQEDVAPTYVYLFDHKGAASFTEIFKGGRNEFYG 470
                          :.|.||:                 |..|......|.....:|:..:..
 Worm   382 --------------TQGIFVS-----------------TATYAEAQANAGGTVYLFQSNQQP--- 412

  Fly   471 ACHAEELQYLFPIGRELFVSAVPTQKDLELRELML-HLWVSFAKTGNPNPTNVSFHLPNWSPASS 534
            :.|..::||.....||.:.::     |:::.:... .:.|:|.|.|:|:|.        |.|...
 Worm   413 SSHVSDMQYFVGTHREDYHTS-----DMDIMDTFYSKMIVNFTKFGSPSPV--------WEPLVP 464

  Fly   535 YPVEFARLGTKMEDSASIF-RLENELMQHRVDFW 567
            ..:.:..|....|  ..|: |:|.:..:..|:||
 Worm   465 SRMNYYALEVNTE--KGIWPRMEEDFHESDVNFW 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_570089.1	COesterase	28..567	CDD:395084	131/552 (24%)
cest-3	NP_510042.2	alpha/beta hydrolases	21..496	CDD:473884	131/552 (24%)