Protein Alignment CG6414 and cest-19

DIOPT Version :10

• Sequence 1: NP_570089.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_509187.4
• Gene: cest-19 / 180973
• WormBaseID: WBGene00020125
• Length: 607
• Species: Caenorhabditis elegans
• Alignment Length: 608
• Identity: 168/608 - (27%)
• Similarity: 263/608 - (43%)
• Gaps: 114/608 - (18%)

  Fly    10 IRVILLCICIQWSDGRNSQCLHV-----RLSHGGWLIGRHLTTHNGRHMRAFMGVPYAEPPLDDL 69
            :|.:|....:.|.........|:     |::.|. :.|..|.| :|:....|.|:|:|.||:..|
 Worm     1 MRWLLSSFILWWHSHLTISTRHISPFELRVNSGA-IRGERLLT-DGQDYSVFKGIPFAMPPVGYL 63

  Fly    70 RFRPPVPKAPWEGERLAIKDAPICLQR-------DPFRRDMILEGSEDCLYLNVYTPERPR-TNG 126
            ||:.|...|.|.|...|.:.:.:|:|.       :|.|  .:...|||||||||::|...: ||.
 Worm    64 RFQMPKEPAKWRGVMNATQYSAMCMQNIDENDAGEPER--YVAHVSEDCLYLNVFSPTPYQYTND 126

  Fly   127 SLPVMVWFHGGGWQCGSG--------ISSFYGPDFLLDHDIVLVSANFRLGPLGFLSTETLDCPG 183
            :.||:|:.|||.:|.|||        :|:|      :...||.|:.|:|||||||.||.....||
 Worm   127 TYPVIVFIHGGRFQTGSGSDIPQRAILSNF------VSRKIVFVTFNYRLGPLGFASTGDSVLPG 185

  Fly   184 NNGLKDQLEVLHWVRANIASFGGDPNSVTVFGESAGGASVTYHMLSEKSRGLLHRGIAQSGTYFN 248
            |.||.||:..|.||:||...|||||:::.:.|...|.||.:...||.::.||..:.:..||:...
 Worm   186 NIGLWDQIWALKWVKANAEVFGGDPSNILLMGHGTGAASASLLALSPRAEGLFQKVLLMSGSALQ 250

  Fly   249 PWAQPAHKGVAAG---RAT-KLAQIVGCGNAGEWPEKLECLRKKPAEDIVASLYDMFVWDFDPMI 309
            |       ||...   .|| .:....|| .|....|.|:|.||:..|:|    :......||...
 Worm   251 P-------GVVRNTQVNATWNMNDRFGC-RAFNSSELLDCARKRSKEEI----FQYKRLHFDDYE 303

  Fly   310 PFPPVVEPEHDGAFLTVAPRQAAKPHGLQLPLMVGATAEEGLLKTAAL----LNLPQLLAE---- 366
            .|.|:::..  |..|...|.|... |..:.|:::|.|.:|..|:...|    ||...:..|
 Worm   304 EFVPIIDGV--GGILPEPPEQLTL-HRRKTPIVIGTTKDESSLRILLLNEKDLNFSSITWENGET 365

  Fly   367 --------FKSQFEQVLPVVLNYDHHDDSVRQTITQRIESFYFKSGHD---YDKANHQNLTDLIS 420
                    || ||:.               .:.|:|..:|.|..:..|   .:.....:|..:.|
 Worm   366 LADNLTLGFK-QFQN---------------HRLISQGCKSEYVWTQVDPSFPESVLFNSLLKMYS 414

  Fly   421 DGWFVAGIDEYLRLRMSQEDVAPTYVYLFDHKGAASFTEIFKGGRNEFYGACHAEELQYLFPIGR 485
            ..|:.|...:.....:..:  .|.|:|.|||. :.:|.:|.:        |.|..:..::|.: .
 Worm   415 HFWYDAPASQLATYYLKHD--LPVYLYSFDHI-SENFYDIDR--------AFHGVDKLHIFNV-T 467

  Fly   486 ELFVSA---VPTQKDLELRELMLHLWVSFAKTGNPNPTNVSFHLPNWSPASSYPVEFARLGTKME 547
            ..|::.   :..|.|..:.|:...|..:||..|.|...|..|.. ||:..::..:.:    ..:.
 Worm   468 PRFLNKRKDMNWQLDQRVVEIFSELVANFALYGTPTHENDGFSF-NWTSTTAKELSY----LSIT 527

  Fly   548 DSASI---FRLENELMQHRVDFW 567
            ||.|:   :|.:..:      ||
 Worm   528 DSPSMQVGYRWQGHV------FW 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_570089.1	COesterase	28..567	CDD:395084	163/588 (28%)
cest-19	NP_509187.4	alpha/beta hydrolases	24..544	CDD:473884	162/583 (28%)