Protein Alignment CG6414 and cest-16

DIOPT Version :9

• Sequence 1: NP_001303565.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_741812.2
• Gene: cest-16 / 180905
• WormBaseID: WBGene00020330
• Length: 697
• Species: Caenorhabditis elegans
• Alignment Length: 675
• Identity: 187/675 - (27%)
• Similarity: 288/675 - (42%)
• Gaps: 158/675 - (23%)

  Fly    12 VILLCICIQWSDGRNSQCLHVRLSHGGW----LIGRHLTTHNGRHMRAFMGVPYAEPPLDDLRFR 72
            ::||.....|::|:     .:..|...|    |:..::...:|:|::.|.||||||||:.:|||:
 Worm     5 LLLLTFIFSWANGQ-----LLEKSRSVWVEQGLVRGNIYNIDGKHIQIFRGVPYAEPPIGELRFK 64

  Fly    73 PPVPKAPWEGERLAIKDAPICLQ------RDPFRRDMILEGSEDCLYLNVYTP-ERPRTNGSLPV 130
            |||.|..|..|..|::..|.|||      .|.|.:..:...|||||||||::| :....:.:.|:
 Worm    65 PPVKKTRWHQELPAVEYGPPCLQFMDFHKNDKFAKTNMDRQSEDCLYLNVFSPYDTDDESKTYPI 129

  Fly   131 MVWFHGGGWQCGS---GISSFYGPDFLLDHDIVLVSANFRLGPLGFLSTETLD-CPGNNGLKDQL 191
            :||.|||.:..||   ||........::...|..||.|:|||||||::.:..| ..||.|:.|.:
 Worm   130 LVWIHGGSFLAGSADTGIDMEVIAANIVSKGIAFVSINYRLGPLGFMNYQNGDKLEGNFGIWDMV 194

  Fly   192 EVLHWVRANIASFGGDPNSVTVFGESAGGASVTYHMLSEKSRGLLHRGIAQSGTYFNPWA----- 251
            ..|.|:::||..|.|||..|||.|||||||:.:...||.|:.||||:.|..||:....||
 Worm   195 MALQWIQSNIKQFNGDPTKVTVMGESAGGAASSLLALSPKTSGLLHQAIIMSGSSMAGWAIHRHS 259

  Fly   252 QPAHKG---VAAGRATK------LAQIVG---------------CGNAG----------EWPEKL 282
            |||:..   ||..|..|      ..::||               |....          ...:|:
 Worm   260 QPAYSVDNLVAYFRCEKWINEDDTKEVVGDEYQHLTHSVIRSALCNYQNVKINCLTDDMTQMDKM 324

  Fly   283 ECLRKK-----P--AEDIVASL-YDMFVWDFDPMIPFPPVVEPEHDGAFLTVAPRQAAKPHGLQL 339
            .||||:     |  .:.:.|.| ....|.|.| ::|        ..|..|.   |..|:     :
 Worm   325 NCLRKELNFSSPLFRKALAAELGVSKMVVDGD-LVP--------SSGVSLV---RNNAR-----I 372

  Fly   340 PLMVGATAEEGLLKTAALLNLPQLLAEFKSQF-EQVLPVVLNYDHHDDS-----------VRQTI 392
            |:|.|...:|...|.|...|:.|.....:|.. |||..::.|..|...|           ...||
 Worm   373 PIMTGVARKEWGHKKAMFYNMHQRDGLKRSDVEEQVYRIIDNSFHETASEKLANSTVQLIANATI 437

  Fly   393 TQRIESFYFKSGHDYDKANHQNLTD--------LISDGWFVAGIDEYLRLRMSQEDVAPTYVYLF 449
            .:.:|:           .|::.:.|        |.||..|||..:..:...:.:.  .|.|:|.|
 Worm   438 VRYLET-----------PNNEFIADQVVGALQKLESDIEFVAPCEREVAAYVDKG--VPVYLYSF 489

  Fly   450 DHKGAASF---------------TEIFKGGRNE------FYGACHAEELQYLFPIGRELFVSAVP 493
            |:...:..               .|:.:..::|      |:|..||    ::|..|........|
 Worm   490 DYVPKSPILESERKIYSLFGTKPVEMKRTEKSEILEKAAFHGLDHA----FIFSKGYSSNFEISP 550

  Fly   494 -TQKDLELRELMLHLWVSFAKTGNPNPTNVSFHLPNWSPASSYPVEFARLGTKME--------DS 549
             |:::..:.:::..:..:|.|.|:|:.|..|:  |.:|..||   ::..|...::        ..
 Worm   551 YTKREETMSKILCTMLTNFVKNGDPSTTRFSW--PIFSGNSS---QYVSLDVPLKLLEGEIHFPD 610

  Fly   550 ASIFRLENELMQHRV--DFWRDLQP 572
            |..:..|.||:...|  |...||.|
 Worm   611 AQFWNTEAELITRYVSKDSETDLDP 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_001303565.1	COesterase	36..567	CDD:278561	179/644 (28%)
		Aes	<116..>254	CDD:223730	59/147 (40%)
cest-16	NP_741812.2	Abhydrolase	25..608	CDD:389770	173/621 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.910