Protein Alignment CG6414 and cest-26

DIOPT Version :10

• Sequence 1: NP_570089.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_001368609.1
• Gene: cest-26 / 180715
• WormBaseID: WBGene00017478
• Length: 585
• Species: Caenorhabditis elegans
• Alignment Length: 582
• Identity: 173/582 - (29%)
• Similarity: 262/582 - (45%)
• Gaps: 93/582 - (15%)

  Fly    35 SHGGWLIGRHLTTHNGRHMRAFMGVPYAEPPLDDLRFRPPVPKAPWEGERLAIKDAPICLQRDPF 99
            :..|.:.|..:...:.|.:..|:|:|:|:.|:.||||:.|.....|:|.:..::..|...|.|.|
 Worm    46 TRNGLVEGFRIKIDDDREVDMFLGIPFAKAPVGDLRFKNPEHTEDWDGVKKCVRFGPRAPQADFF 110

  Fly   100 --RRDMILEGSEDCLYLNVYTP---ERPRTNGSLPVMVWFHGGGWQCGSGISSFYGPD----FLL 155
              |..:.:..|||||||||::|   ....:||..||||:.||||:...|.:.  ||.:    :|.
 Worm   111 WERFTLGVGKSEDCLYLNVFSPTWKAEEVSNGLHPVMVYVHGGGFLIDSAVK--YGDEGIAKYLC 173

  Fly   156 DHDIVLVSANFRLGPLGFLSTETLDCPGNNGLKDQLEVLHWVRANIASFGGDPNSVTVFGESAGG 220
            .|.:|:|:..:|||.|||.||....||||.||.|....|.|||.|:.:|||||..|||||:||||
 Worm   174 RHGVVVVTIQYRLGLLGFFSTGDQVCPGNLGLWDMTMALQWVRDNVHAFGGDPRKVTVFGQSAGG 238

  Fly   221 ASVTYHMLSEKSRGLLHRGIAQSGTYFNPWAQPAHKGVAAGRATKLAQIVGCGNAGEWPEKLECL 285
            .||....||..||.|.|:.:..:|.....|:.     |...|.....:        |:..: :|.
 Worm   239 VSVDLLSLSPHSRDLFHQVVPMAGNGECEWST-----VGKNRLVNACR--------EFAYR-KCW 289

  Fly   286 RKKPAEDIVASLYDMFVWDFDPMIPFPPV-VEPEHDGAFLT------------VAPRQAAKPHGL 337
            .:|.|.|..||         :.|:.|... .|.|.:...||            :||...:||...
 Worm   290 DEKQARDENAS---------ESMLEFLRTRKEREFEKRLLTRKGVDVSKIGLDLAPVIGSKPSDF 345

  Fly   338 QLP--------------LMVGATAEEGLLKTAALLNLPQLLAEFKSQFEQVLPVVLNYDHHDDSV 388
             ||              :|||....||||  .|.|. |....|  ...:::|.:::..::|:|.
 Worm   346 -LPKSIEELRKEAPKKNIMVGTCEHEGLL--FASLG-PSNFDE--KGIDKLLALLITEENHEDF- 403

  Fly   389 RQTITQRIESFYFK--SGHDYDK-ANHQNLTDLISDGWFVAGIDEYLRLRMSQEDVAPTYVYLFD 450
             :.:.:..:..|.|  |..:.|| ...:....|.||.:...|...|.. :|::.. ...::|.||
 Worm   404 -EALREEAKKMYLKKLSDDEDDKEVAARGYIQLYSDLFVNNGTYNYAE-KMTKLG-NKVFMYSFD 465

  Fly   451 HKGAASFTEIFKGGRNEFYGACHAEELQYLFPIGRELFVSAVPTQKDLELRELMLHLWVSFAKTG 515
            :....||..:  ..|..|..|.|..||.|:|  |..:..:....:.|..:.:||..:|.:|||.|
 Worm   466 YCNPRSFGIL--SLRAPFRAATHCTELAYIF--GVSIVFNYRYNESDRAMLDLMTKMWTNFAKYG 526

  Fly   516 NPN-----PTNVSFHLPNWSPAS-SYPVEFARLGTKMEDSASIFRLENELMQHRVDFWRDLQ 571
            |||     .|...|   .|.|.| ..|..|..:..|..:..::::      .:|.:||:.::
 Worm   527 NPNGQYEDSTVFDF---KWEPTSKEEPTNFLAINEKKCEMQTVYQ------DNRAEFWKKIK 579

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_570089.1	COesterase	28..567	CDD:395084	171/576 (30%)
cest-26	NP_001368609.1	COesterase	40..575	CDD:395084	171/576 (30%)