Protein Alignment CG6414 and cest-2.3

DIOPT Version :9

• Sequence 1: NP_001303565.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_506510.2
• Gene: cest-2.3 / 179918
• WormBaseID: WBGene00013873
• Length: 665
• Species: Caenorhabditis elegans
• Alignment Length: 575
• Identity: 155/575 - (26%)
• Similarity: 243/575 - (42%)
• Gaps: 101/575 - (17%)

  Fly    32 VRLSHG---GWLIGRHLTTHNGRHMRAFMGVPYAEPPLDDLRFRPPVPKAPWEGERLAIKD-API 92
            ::||.|   |.::....:....:....|:|:||.|||:.:||||.|.....|||. |..|| .|.
 Worm    20 IQLSTGTIEGKILNATYSPFGNQTATVFLGIPYVEPPIGELRFRKPRLLKSWEGV-LETKDYKPA 83

  Fly    93 CLQ--RDPFRRDMILEGSEDCLYLNVYTPERPRTNGSLPVMVWFHGGGWQCGSGISSFYGPDFLL 155
            |:.  |..|:...:.|.||||||.||:|.:....|.:..||:..|||...|.||  |.:.|:..:
 Worm    84 CMSYWRKTFKNGFVGEISEDCLYANVFTNQYCLQNKNCSVMIVVHGGRLVCESG--SAFKPEIFI 146

  Fly   156 ------DHDIVLVSANFRLGPLGF--LSTETLDCPGNNGLKDQLEVLHWVRANIASFGGDPNSVT 212
                  |.:||:|:.|:|||..||  .:.||.|.  |..:.|.||.:.|||..|..|||:.:.:|
 Worm   147 NNFVGQDRNIVVVTFNYRLGVFGFGVFNGETGDT--NVAMYDMLEAVKWVRKEIDQFGGNKDRIT 209

  Fly   213 VFGESAGGASVTYHMLSEKSRGLLHRGIAQSGTYFNPWAQPAHKGVAAGRATKLAQIVGCGNAGE 277
            :.|.|||...:.....|..|:||||:.|..|....:.......||:     |.:||.|||.....
 Worm   210 MAGHSAGAGLIVDFTSSTLSKGLLHQQIVMSAPLQDISKSANFKGM-----TIVAQNVGCIPKEY 269

  Fly   278 WPEKLE---------CLRKKPAEDIVASLYDM-----FVWDFDPMIPFPPVVEPEHDGAFLTVAP 328
            ...||.         ||:.|.|:|::.:...|     |.:.           .|..||.|:|..|
 Worm   270 GFRKLSKTQINKTYLCLQNKSAQDLLHAQLSMQQNSTFYFG-----------SPRVDGDFITDYP 323

  Fly   329 RQAAKPHGL-QLPLMVGATAEEGLLKTAALLNLP-------QLLAEFKSQFEQVLPVVLNYDHHD 385
            ......:.: .:...:|.|.  |.|:.:..:..|       |||   |:..|.|     .|:
 Worm   324 DNLFNFNTIYPINTFIGTTT--GELRDSLYITDPKNDRIKEQLL---KNMCEHV-----GYE--- 375

  Fly   386 DSVRQTITQRIESFYFKSGHDYDKANHQNLTD---LISDGWFVAGIDEYLRLRMSQEDVAPTYVY 447
                  :.::.|.|..|.|:.|     :|.||   |..|..|.:|..:.........  :..::|
 Worm   376 ------LFEKPEEFTKKCGNYY-----KNGTDAQFLSDDMEFYSGAIKVANAHKRAN--SKVFMY 427

  Fly   448 LFDHKGAASFTEIFKGGRNEFYGACHAEELQYLFPIGRELFVSAVPTQKDLELRELMLHLWVSFA 512
            .:|:|||.:....:.    |.....|:|:|.|.|...|..||:     ||..:..:...:..:|.
 Worm   428 SYDYKGAGTAFHKYL----EAPSPHHSEDLIYTFGTSRGPFVA-----KDYVIERIYSGMLANFI 483

  Fly   513 KTGNPNPTNVSFHLPNWSPASSYPVEFARLGTKMEDSASIFRLENELMQHRVDFW 567
            ...:|:|:...    .|...:....|:..:  ..:.:.::..:::......:|||
 Worm   484 NFEDPSPSKTQ----QWRQYTQEKREYFLI--DFDKNFTMPGMKDHYYTRALDFW 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_001303565.1	COesterase	36..567	CDD:278561	151/569 (27%)
		Aes	<116..>254	CDD:223730	50/145 (34%)
cest-2.3	NP_506510.2	Abhydrolase	20..532	CDD:389770	153/573 (27%)
		CemA	<550..>647	CDD:383495

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910