Protein Alignment CG6414 and cest-1.1

DIOPT Version :9

• Sequence 1: NP_001303565.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_506506.1
• Gene: cest-1.1 / 179915
• WormBaseID: WBGene00011362
• Length: 673
• Species: Caenorhabditis elegans
• Alignment Length: 522
• Identity: 139/522 - (26%)
• Similarity: 235/522 - (45%)
• Gaps: 77/522 - (14%)

  Fly    29 CLHVRLSHG---GWLIGRHLTTHNGRHMRAFMGVPYAEPPLDDLRFRPPVPKAPWEGERLAIKDA 90
            |..|:||.|   |.::....:....:....|:|:|:.|||:.|||:|.|.|...|||..:..:..
 Worm    16 CKRVQLSSGTIEGKILNISYSPLGNQSATVFLGIPFVEPPIGDLRYRKPRPPKSWEGVLVTNEYK 80

  Fly    91 PICLQ------RDPFRRDMILEGSEDCLYLNVYTPERPRTNGSLPVMVWFHGGGWQCGSGISSFY 149
            ..|:.      ::.|...:    |||||||||.|.|....|.:..||:..||||:...|  :|.:
 Worm    81 SACMSNATKTYKNKFGGPI----SEDCLYLNVLTNEYCLENKNCSVMMIVHGGGYLTES--ASTF 139

  Fly   150 GPDFLLDH------DIVLVSANFRLGPLGFLSTETLDCPGNNGLKDQLEVLHWVRANIASFGGDP 208
            .|:.|:::      :||:|:.|:|||...|..........|.||.|.:|.::|||..|.:|||:.
 Worm   140 NPEILINNFVGQGRNIVVVTFNYRLGLFSFGQFNGDRGDKNFGLYDMIESVNWVRREIENFGGNK 204

  Fly   209 NSVTVFGESAGGASVTYHMLSEKSRGLLHRGIAQSGTYFNPWAQPAHKGVAAGRATKLAQIVGC- 272
            |.:|:.|.|||.:.:.....|..::||:|:.|..|....|...:...||:     |.:||:|||
 Worm   205 NRITLAGHSAGASMIVAFTSSPLTKGLVHQQIIMSAPMTNMSKKSNFKGM-----TVMAQMVGCL 264

  Fly   273 ------GNAGEWPEKLE----CLRKKPAEDIVASLYDMFVWDFDPMIPF---PPVVEPEHDGAFL 324
                  ....|  |::|    |||||.|:.|:    |..:|.......|   ||:  .||   ||
 Worm   265 SEEIGFNKLSE--EQVENTYSCLRKKSAQQIL----DAQLWLLQNSTYFLGAPPI--DEH---FL 318

  Fly   325 TVAPRQA-AKPHGLQLPLMVGATAEEGLLKTAALLNLPQLLAEFKSQFEQVLPVVLNYDHHDDSV 388
            |..|... |......:..::|.|..|  ::.::.: :....|:.|.:..:.|...:.|..:::.
 Worm   319 TDYPENLYASKSIYPINTLIGTTTLE--VEESSYI-IDPAFADKKVELLENLCDHIGYVLYEEP- 379

  Fly   389 RQTITQRIESFYFKSGHDYDKANHQNLTDLISDGWFVAGIDEYLRLRMSQEDVAPTYVYLFDHKG 453
             :|.:::.:..|.......:.:|...        ::...|| :.....|..  ...::|.:|::|
 Worm   380 -ETFSKKCQKQYMNGNSSMNLSNEME--------FYTPAID-FADSHTSGN--TKVFLYSYDYRG 432

  Fly   454 AASFTEIFKGGRNEFYGACHAEELQYLFPIGRELFVSAVPTQKDLELRELMLHLWVSFAKTGNPN 518
            |....:.:...|:..    |:|:|.|:|...|.:|     ..||..:.::...::..|....||.
 Worm   433 AGPAYDRYLEVRSPH----HSEDLIYVFGTHRGIF-----APKDYIIEKIYSGMFADFVNFENPL 488

  Fly   519 PT 520
            |:
 Worm   489 PS 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_001303565.1	COesterase	36..567	CDD:278561	135/515 (26%)
		Aes	<116..>254	CDD:223730	47/143 (33%)
cest-1.1	NP_506506.1	COesterase	19..531	CDD:278561	138/519 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910