Protein Alignment CG6414 and cest-1.2

DIOPT Version :9

• Sequence 1: NP_001303565.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_506504.2
• Gene: cest-1.2 / 179914
• WormBaseID: WBGene00011364
• Length: 676
• Species: Caenorhabditis elegans
• Alignment Length: 558
• Identity: 145/558 - (25%)
• Similarity: 225/558 - (40%)
• Gaps: 112/558 - (20%)

  Fly    12 VILLCICIQWSDGRNSQCLHVRLSHG---GWLIGRHLTTHNGRHMRAFMGVPYAEPPLDDLRFRP 73
            :|...:.:.|...:.:....|:||.|   |..:....:....:...||:|:||.|||:.|||||.
 Worm     1 MIFKFVVLLWFSAQFAISTKVQLSTGIIEGKQLNSTYSPFGNQSAIAFLGIPYVEPPIGDLRFRK 65

  Fly    74 PVPKAPWEGERLAIKDAPICLQRD-----------PFRRDMILEGSEDCLYLNVYTPERPRTNGS 127
            |.|:..|.|.....|..|.|:...           |.        |||||||||.|.:....|.:
 Worm    66 PRPQKTWSGVLETKKFKPACMSNSTKTYKNGGIGGPI--------SEDCLYLNVLTNQYCLENKN 122

  Fly   128 LPVMVWFHGGGWQCGSG--------ISSFYGPDFLLDHDIVLVSANFRLGPLGFLSTETLDCPGN 184
            ..|::..||||:...|.        :::|.|.    |.:||:|:.|:|||..||......:...|
 Worm   123 CSVVIIVHGGGYLFESAATFNHEILVNNFVGQ----DRNIVVVTINYRLGIFGFGHLNGFEGDKN 183

  Fly   185 NGLKDQLEVLHWVRANIASFGGDPNSVTVFGESAGGASVTYHMLSEKSRGLLHRGIAQSGTYFNP 249
            .|:.|.||.:.|||..|..|||:.:.:|:.|.|||...|....:|..::||:|:.|..||...|.
 Worm   184 VGIFDTLEAVKWVRREIKQFGGNKDRITLAGHSAGAGVVAAFTISPLTKGLIHQQIVMSGPMTNM 248

  Fly   250 WAQPAHKGVAAGRATKLAQIVGCGNA----GEWPEK-----LECLRKKPAEDIVASLYDMFVWDF 305
            ..:...||:     |.:|:.|||.:.    .:.||.     ..|||||||::    |.|..:|..
 Worm   249 SKKSNFKGM-----TAMAERVGCHSKKYGFNKLPEHEVEQVYSCLRKKPAQE----LLDAQLWLL 304

  Fly   306 DPMIPF---PPVVEPEHDGAFLTVAPRQAAKPHGL-QLPLMVGATAEEGLLKTAALLNLPQLLAE 366
            .....:   |||     ||.|:|..|........: .:..::|.|..| |..|..:.|......|
 Worm   305 QNSTFYFGAPPV-----DGEFITDYPDNLYSEKSIFSINTLLGTTTRE-LQDTGYISNSNYSKFE 363

  Fly   367 FKSQFEQVLPVVLNYDHHDDSVRQTITQRIESFYFKSGHDYDKANHQNLTDLISDGWFVAGID-- 429
            .|..|                 .:.:..:|....:|...|:.....:         |::.|.|
 Worm   364 TKETF-----------------LKNLCDQIGIEIYKESEDFSSKCQK---------WYINGSDSK 402

  Fly   430 ------EYLRLRMSQEDV-----APTYVYLFDHKGAA-SFTEIFKGGRNEFYGACHAEELQYLFP 482
                  |:....::..|.     ...|:|.:.:.||. :|.:..|     .....|:|:|.|.|.
 Worm   403 SLSDDMEFYTQAINLADAHARKGKKVYMYSYAYSGAGPAFKKYMK-----VKSPHHSEDLIYTFG 462

  Fly   483 IGRELFVSAVPTQKDLELRELMLHLWVSFAKTGNPNPT 520
            ..|.:|     ..||..:..:...::..|....:|:|:
 Worm   463 THRGVF-----APKDYVIEYIYSGMFADFINFEDPSPS 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_001303565.1	COesterase	36..567	CDD:278561	140/534 (26%)
		Aes	<116..>254	CDD:223730	47/145 (32%)
cest-1.2	NP_506504.2	COesterase	21..536	CDD:278561	143/538 (27%)
		Aes	<125..>250	CDD:223730	44/128 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910