Protein Alignment CG6414 and cest-33

DIOPT Version :9

• Sequence 1: NP_001303565.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_504621.1
• Gene: cest-33 / 179020
• WormBaseID: WBGene00017431
• Length: 554
• Species: Caenorhabditis elegans
• Alignment Length: 578
• Identity: 173/578 - (29%)
• Similarity: 238/578 - (41%)
• Gaps: 142/578 - (24%)

  Fly    37 GGWLIGRHLT--------------------THNGRHMRAFMGVPYAEPPLDDLRFRPPVPKAPWE 81
            ||:|  .|||                    .|:...:..::|:|||:||:.:|||:.||....|.
 Worm     2 GGFL--SHLTPEQNVEALKASCGPVRGNIYKHDDVIVDGYLGIPYAKPPVGELRFKKPVTVDVWT 64

  Fly    82 GERLAIKDAPICLQRDPFRRDMILEG-------SEDCLYLNVYTPERPRT---NGSLPVMVWFHG 136
            ..:...|..|.|:|...|.:   :.|       ...||.|||:||....:   ||. ||||:.||
 Worm    65 EIKDCYKYGPACVQTGGFEQ---IAGPRTPTPEEAGCLTLNVFTPRNASSEFKNGR-PVMVYIHG 125

  Fly   137 GGWQ-CGSGISSFYGPDFLLD-HDIVLVSANFRLGPLGFLSTETLDCPGNNGLKDQLEVLHWVRA 199
            ||:: |.|.....|.....|. .|:|:||.|:|||..|||:|....||||.||.||...|.||:.
 Worm   126 GGYELCASSDFCAYSLSGTLPLKDVVVVSINYRLGVFGFLTTGDNVCPGNFGLWDQTLALKWVQK 190

  Fly   200 NIASFGGDPNSVTVFGESAGGASVTYHMLSEKSRGLLHRGIAQSGTYFNPWAQPAHKGVAAGRAT 264
            :|:|||||||.|||||:||||||.....||..||.|..|.|..|||        ||...|...:.
 Worm   191 HISSFGGDPNCVTVFGQSAGGASTDLLSLSPHSRDLFQRFIPISGT--------AHCDFAIRASE 247

  Fly   265 KLAQIVG-----CGNAG-------EW-----PEKLECLR--KKPAEDIVASLYDMFVWDFDPMIP 310
            ..|:|..     .|.:|       :|     ||.|..::  ||.....:..:
 Worm   248 NQAKIFREFAEFHGFSGRDSSALFKWYQEQSPETLSNVKGYKKSISGFLTFI------------- 299

  Fly   311 FPPVVEPEHDGAFLTVAPRQAAKPHGLQLPLMVGATAEEGLLKTAALLNLPQLLAEFKSQFE--- 372
                  |..||.|.. .|....:....:..:|.|.|..|||           :||.....|.
 Worm   300 ------PNLDGDFFP-KPLDELRKEAPKKQMMTGVTEYEGL-----------MLASMNPAFSPAD 346

  Fly   373 ---QVLP-------VVLNYDHHDDSVRQTITQRIESFYFKSGHDYDK----ANHQNLTDLISDGW 423
               .::|       ||.|.|.         .|:|  ||.|.....||    |..:.|.:.:.|.:
 Worm   347 VGLTLMPQGIYGKDVVSNPDE---------IQKI--FYEKYVEGVDKSDELAMRKKLCEALGDEF 400

  Fly   424 FVAGIDEYLRLRMSQEDVAPTYVYLFDHKGAASFTEIFKGGRNEFYGACHAEELQYLFPIGRELF 488
            |..|:.:  ..:.:.:.....|.|.|::....||.  ...|...|..|.|..||:||  :|..::
 Worm   401 FNVGVIQ--AAKNAAKHGNEVYFYTFEYVNPDSFG--MWDGMMPFKAAVHCTELRYL--LGEGVY 459

  Fly   489 VSAVPTQKDLELRELMLHLWVSFAKTGNPNPTNVSFHLPNWSPAS----------SYP 536
            ....||::|.::.|....|:.:|||.||||....:..:  |...|          |||
 Worm   460 SKFEPTEEDRKVMETTTTLFSNFAKYGNPNGKGATAEI--WEKYSLNRPERHYRISYP 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_001303565.1	COesterase	36..567	CDD:278561	173/578 (30%)
		Aes	<116..>254	CDD:223730	69/142 (49%)
cest-33	NP_504621.1	Esterase_lipase	16..521	CDD:238191	167/562 (30%)
		Aes	<103..>224	CDD:223730	61/121 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	221	1.000	Domainoid score	I1491
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm14771
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.710