Protein Alignment CG6414 and cest-24

DIOPT Version :10

• Sequence 1: NP_570089.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_504613.1
• Gene: cest-24 / 179017
• WormBaseID: WBGene00020891
• Length: 658
• Species: Caenorhabditis elegans
• Alignment Length: 581
• Identity: 166/581 - (28%)
• Similarity: 249/581 - (42%)
• Gaps: 101/581 - (17%)

  Fly    24 GRNSQCLHVRLSHGGWLIGRHLTTHNGRHMRAFMGVPYAEPPLDDLRFRPPVPKAPWEGERLAIK 88
            |::...: ||:.. |.|.|..:.|..|.....|.|:||||||:.:|||:.|.|...|||.|...|
 Worm    91 GKSENAI-VRVQQ-GLLEGFRVKTAKGDLCDVFHGIPYAEPPVGELRFQKPQPPKAWEGIRKCNK 153

  Fly    89 DAPICLQRD-PFRRDMILEG---SEDCLYLNVYTPERPRTNGSLPVMVWFHGGGWQCGSGISSFY 149
            .....:.:: |:  |..|..   |||||||||:.| :.|.:...||:.:.||||:...|  :..|
 Worm   154 YPNRSIHKEMPW--DKALPSANQSEDCLYLNVFAP-KIREDKKYPVLFYIHGGGYVMDS--AERY 213

  Fly   150 GP----DFLLDHDIVLVSANFRLGPLGFLSTETLDCPGNNGLKDQLEVLHWVRANIASFGGDPNS 210
            ..    ..|:..:|::|:.::|||.||||||....||||.||.|.||.:.||.|||:||||||.:
 Worm   214 TAKNICKLLVSREIIVVTFHYRLGFLGFLSTGDDVCPGNYGLFDMLEAMRWVHANISSFGGDPEN 278

  Fly   211 VTVFGESAGGASVTYHMLSEKSRGLLHRGIAQSGTYFNPWAQPAHKGVAAGRATKLAQIVGCGNA 275
            :|:.|:|||.|:......|..::||..|.|...|..:..||..::..:.. ...|.|:.:|
 Worm   279 ITLSGQSAGAAAADLLSFSPLTKGLFKRKIVMGGNSYCHWATTSNHDIRE-YCKKWAKRLG---- 338

  Fly   276 GEWPEKLECLRKKPAEDIVASLYD----------MFVWDF---DPMIPFPPVVEPEHDGAFLTVA 327
              |..:|....|:.....:.:.::          ||..:.   :..:|..||:    ||..|
 Worm   339 --WKPQLNYANKREESVDIFNFFNGLPTSKLGMTMFFSNTIFKECQLPLAPVI----DGEIL--- 394

  Fly   328 PRQAAKPHGLQ--------LPLMVGATAEEGLLKTAALLNLPQLLAEFKSQFEQVLPVVLNYDHH 384
                  ||.|:        :|.:||....|.||..|.     .||...:.:....:.|:...:..
 Worm   395 ------PHDLKVLRETQEHVPSLVGGGEYEALLFCAI-----GLLRGTEKEINSAIDVLSRKNRL 448

  Fly   385 DDSVRQTITQRI--ESFYFKSGHDYDKANHQNLTDLISDGWFVAGIDEYLRLRMSQEDVAPTYVY 447
            ..|..:.:|:::  :|...::.   .||.......||||  ..|....|..:|..|:.....|.|
 Worm   449 SRSKIEAMTEKVYGDSPALRAD---SKARKMFFVQLISD--IFANYGNYRFMRDCQQRGVECYGY 508

  Fly   448 LFDHK-----GAASFTEIFKGGRNEFYGACHAEELQYLF-------PIGRELFVSAVPTQKDLEL 500
            .|||:     |.......|.||       .|..||.|||       |:|.        .:.|..:
 Worm   509 SFDHQSKQMWGWLQHVVPFTGG-------THTSELSYLFDCNYMSAPLGM--------NKTDKVV 558

  Fly   501 RELMLHLWVSFAKTGNPNPTNVSFHLPNWSPASSYPVEFARLGTK----MEDSASIFRLEN 557
            ..:....:.:|.|.|.||..|  ..||.|...|........:..|    |:.:...:|::|
 Worm   559 SGMTADYFTNFVKFGTPNGPN--SQLPKWERISPDDEHMKLISIKPEPEMKTTVYGYRMQN 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_570089.1	COesterase	28..567	CDD:395084	165/577 (29%)
cest-24	NP_504613.1	COesterase	97..608	CDD:395084	163/564 (29%)