Protein Alignment CG6414 and cest-35.1

DIOPT Version :10

• Sequence 1: NP_570089.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_504400.1
• Gene: cest-35.1 / 178912
• WormBaseID: WBGene00015067
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 581
• Identity: 156/581 - (26%)
• Similarity: 254/581 - (43%)
• Gaps: 102/581 - (17%)

  Fly    26 NSQCLHVRLSHGGWLIGRHLTTHNGRHMRAFMGVPYAEPPLDDLRFRPPVPKAPWEGERLAIKDA 90
            |:.|..:|         .::..|:.:.:..::|:|:|:.|:.:|||:..|....|.......|..
 Worm    18 NASCGPIR---------GNIYEHDDKIVDGYLGIPFAKAPIGELRFKKSVEAEKWTEPLDCYKYG 73

  Fly    91 PICLQRDPF------RRDMILEGSED-CLYLNVYTP-----ERPRTNGSLPVMVWFHGGGWQCGS 143
            |.|.|....      :...|.|.:|| ||.|||:.|     |.|  || |||:|:|:|||::.
 Worm    74 PGCPQSGALGAMIVPQASAIREFAEDNCLTLNVFAPKWKSAEFP--NG-LPVIVYFYGGGFEV-- 133

  Fly   144 GISSFYGPDFLLD-----HDIVLVSANFRLGPLGFLSTETLDCPGNNGLKDQLEVLHWVRANIAS 203
            |.||.: .|:.|.     .|::||:.|:|:|||||.:|......||.||.||...|.||:.:|.|
 Worm   134 GFSSMF-DDYSLTGTLPLKDVILVTPNYRIGPLGFFATGDDVSRGNWGLWDQALALQWVQKHIKS 197

  Fly   204 FGGDPNSVTVFGESAGGASVTYHMLSEKSRGLLHRGIAQSGT---------------YFNPWAQP 253
            |||||::||:.|.|||||||.:..||..:....|:.|..||.               .|..:|:
 Worm   198 FGGDPSNVTISGTSAGGASVDFLSLSPHANKYFHKFIPMSGAATCPFGIRSKDVEGLIFREFAK- 261

  Fly   254 AHKGVAAGRATKLAQIVGCGNAGEWPEKLECLRKKPAEDIVASLYDMFVWDFDPMIPFPPVVEPE 318
             |.|.|             ||..|  ..|...:.:.||..:.:  :.|.:....|..|    .|.
 Worm   262 -HHGYA-------------GNDSE--SLLHWYQSQDAEIFLKA--EGFKYPASGMFSF----VPN 304

  Fly   319 HDGAFLTVAPRQAAKPHGLQLPLMVGATAEEGLLKTAALLNLPQLLAEFKSQFEQVLPVVLNYD- 382
            :||.|.. .|....:....:|..:|.....||       |...:.....||. ::||...|..:
 Worm   305 YDGDFFP-KPFDELRKEAPKLDAIVSVAEYEG-------LGFEEFYPGQKSP-QEVLTAALGPEV 360

  Fly   383 --HHDDSVRQTITQRIESFYFKSGHDYDKANHQNLTDLISDGWFVAGIDEYLRLRMSQEDVAPTY 445
              :.::.|::.:...:|:...|||....|    .|.::..|.:|..|:.:.:|......:    .
 Worm   361 VRNREEVVKKAVEAYLENIEDKSGEKIGK----KLVEIFGDYYFSVGVFDTVRSLAKYGN----N 417

  Fly   446 VYLFDHKGAASFTEIFKGGRNEFYGACHAEELQYLFPIGRELFVSAVPTQKDLELRELMLHLWVS 510
            |||.........|.|..|....|..|.|..:::|:...|...|     :::|.::.::|.....:
 Worm   418 VYLSSFNYFNPETPIMFGENRPFNAASHGCDIRYILGDGIGEF-----SKEDRKVMDMMGTYLTN 477

  Fly   511 FAKTGNPNPTNVSFHLPNWS---PASSYPVEFARLGTKMEDS--ASIFRLENELMQHRVDF 566
            |||.||||...||.....:|   |...:.:::.:  .:|.|:  ...:::.:|:.:|.:.:
 Worm   478 FAKYGNPNGKGVSIPWEKYSLDNPGRYFKIDYPK--CEMADNFLDGRYKIIDEVNEHGIQY 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_570089.1	COesterase	28..567	CDD:395084	155/579 (27%)
cest-35.1	NP_504400.1	COesterase	16..523	CDD:395084	154/566 (27%)