Protein Alignment CG6414 and cest-10

DIOPT Version :10

• Sequence 1: NP_570089.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_501133.3
• Gene: cest-10 / 177493
• WormBaseID: WBGene00016595
• Length: 579
• Species: Caenorhabditis elegans
• Alignment Length: 549
• Identity: 115/549 - (20%)
• Similarity: 209/549 - (38%)
• Gaps: 131/549 - (23%)

  Fly    56 FMGVPYAEPPLDDLRFRPPVPKAPWEGERLAIKDAPICLQRDPFRRDMILEGSEDCLYLNVYTPE 120
            |..:|:|:|||..|||:.|.|...|.|.|.|....|.|:......:.:.....||||:||::|.|
 Worm    42 FKKIPFAKPPLGKLRFQKPQPAETWNGVRNAKDYGPACMSNSSTTKTVQKWVDEDCLHLNIFTSE 106

  Fly   121 RPRTNGSLPVMVWFHGGGWQCGSGISSFYGPDFLL----DHDIVLVSANFRLGPLG-FLSTETLD 180
            ....:.:..|:::.|||.....|.:  .:...|||    ..:||.|....|||... |:..:...
 Worm   107 TCLKSKNCAVVIYLHGGNLHYDSAV--MFNDTFLLHTYASQEIVFVIPAVRLGIFSHFVVEDQSI 169

  Fly   181 CPGNNGLKDQLEVLHWVRANIASFGGDPNSVTVFGESAGGASVTYHMLSEKSR-----GLLHRGI 240
            .|.|..|.|.|:.:.:.:::|.:|||:....|:.|.|.||...:  |||..::     .|..:.|
 Worm   170 APNNLALFDMLQAMEFAKSDIHNFGGNNKRTTLLGHSYGGTVAS--MLSFSTKVNTDLSLFQQYI 232

  Fly   241 AQSG-TYFNPWAQPAHKGVAAGRATKLAQIVGC-GNAGEWPEK-------LECLRKKPAEDIV-- 294
            :.|. |.|:...      :...|..:.|:...| ....::..|       .:||:||.|.:::
 Worm   233 SMSSPTNFDTLE------LQVERTYRFAEHANCLPKNSKFMRKNQKEVYMRDCLKKKSASELLRI 291

  Fly   295 -ASLYDMFVWDFDPMIPFPPVVEPEHDGAFLTVAPRQAAKPHGLQLPLMVGATAEEGLLKTAALL 358
             .||.:.....:...:...|:.:...:..|:.       .|:  .:..:.|.|..|.|:
 Worm   292 QRSLEEAGYPVYGGSVMRGPIFQEVLERDFMD-------SPN--NITSLTGCTKYESLV------ 341

  Fly   359 NLPQLLAEFKSQFEQVLPVVLNYDHHDDSVR-------QTITQRIESFYFKSGHDYDKANHQNLT 416
                                  |||:.:..:       :.:.::..|...:...::|  |.:|.|
 Worm   342 ----------------------YDHYRNMGKALGFENYEEVNEKYRSDSKEGKIEFD--NVKNAT 382

  Fly   417 DLISDGWFVAGIDEYLRLRMSQEDVAPTYVYLFDHKGAASFTEIFKGGRNEFYGACHAEELQYLF 481
            .::.       |....|:....:...|.|.|.:.:...|:                |.::|  .|
 Worm   383 QIML-------IQIRTRVNKILKKNIPAYHYEYAYPKHAN----------------HTDDL--FF 422

  Fly   482 PIGRELFVSAVPTQKDLELRELMLHLWVSFAKTGNP-------NPTNVSFHLPNWSPAS-SYPVE 538
            .:|...|:.   .:.:::|......::::|.|||||       |....::...||:..: ..||
 Worm   423 IMGVHPFIQ---DENEIKLGNFYRSMFLNFIKTGNPGNGCDGANLNGSTYFEVNWNETTGERPV- 483

  Fly   539 FARLGTKMEDSASIFRLENELMQHRVDFW 567
                            ::|...|..:|:|
 Worm   484 ----------------MKNNFEQKILDYW 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_570089.1	COesterase	28..567	CDD:395084	114/547 (21%)
cest-10	NP_501133.3	alpha/beta hydrolases	20..503	CDD:473884	115/549 (21%)