Protein Alignment CG6414 and cest-6

DIOPT Version :9

• Sequence 1: NP_001303565.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_501070.1
• Gene: cest-6 / 177459
• WormBaseID: WBGene00020688
• Length: 583
• Species: Caenorhabditis elegans
• Alignment Length: 561
• Identity: 126/561 - (22%)
• Similarity: 213/561 - (37%)
• Gaps: 118/561 - (21%)

  Fly    40 LIGRHLTTHNGRHM---RAFMGVPYAEPPLDDLRFRPPVPKAPWEGERLAIKDAPICLQRDPFRR 101
            :|...|.:.||..:   :.|..:|:|:||:..|||:.|:....|||...|.:..|.|:......:
 Worm    25 VITTSLGSINGNQIGSYQTFKKIPFAKPPIGKLRFQKPMAAEKWEGILNATEYGPACMSNSSTSK 89

  Fly   102 DMILEGSEDCLYLNVYTPERPRTNGSLPVMVWFHGGGWQCGSGISSFYGPDFLLD----HDIVLV 162
            .......||||::|::|.:...::.:..|:.:.|||.....|.:  .:...:|.|    .|::||
 Worm    90 SPQKWIDEDCLHINIFTTDTCLSSKNCSVVFYVHGGELVYDSAV--MFEDKYLFDTFSSRDVILV 152

  Fly   163 SANFRLGPLGFLSTETLD-CPGNNGLKDQLEVLHWVRANIASFGGDPNSVTVFGESAGGASVTYH 226
            ...||||.......|..: .|.|..|.|.|..|.:|::.|.:|||..:.||.||.|.||..|:..
 Worm   153 IPAFRLGLFSHFVVEDQNVAPNNLALYDILLALEFVKSEIHNFGGSSDRVTAFGHSYGGHVVSVM 217

  Fly   227 MLSEK---SRGLLHRGIAQSGTYFNPWAQPAHKGVAAGRATKLAQIVGCGNAGEWPEK------- 281
            ..|.:   ......|.|..|..  |.|.....:   ..:..:..|...|....:...:
 Worm   218 AFSTEINTDLSYFQRVICMSSV--NVWDSLEFE---IEKTMRFIQYANCSVPQDLKSRMTSFEQD 277

  Fly   282 ---LECLR----------KKPAEDIVASLYDMFVWDFDPMIPFPPVVEPEHDGAFLTVAPRQAAK 333
               :|||:          ::..||....:|...|.. :|:|. ..:|:..::            |
 Worm   278 SYMMECLQDIDSMELLRIQRSLEDEGHPIYSGLVLR-EPLIQ-NVLVQDFYE------------K 328

  Fly   334 PHGLQLPLMVGATAEEGLLKTAALLNLPQLLAEFKSQFEQVLPVVLNYDHHDDSVRQTITQRIES 398
            |.  .:|.:.|.|.:| |.|..|..|:.:.|.     :|       ||...||..|..
 Worm   329 PK--NIPTLTGCTYKE-LDKFHAYHNIVETLG-----YE-------NYKECDDKYRDD------- 371

  Fly   399 FYFKSGHDYDKANHQNLTDLISDGWFVAGIDEYLRLRMSQ--EDVAPTYVYLFDHKGAASFTEIF 461
              .|.|. :|...|.:.|         .||....:|::.:  :...|||.|.:.:....|
 Worm   372 --RKYGR-FDLNKHADET---------FGILAQTKLKVDKQLDKGIPTYFYEYSYPKHPS----- 419

  Fly   462 KGGRNEFYGACHAEELQYLFPIGRELFVSAVPTQKDLELRELMLHLWVSFAKTGNPNPTNVSFHL 526
                       |.::|.|:  :|...|..   .:.::.|.:....::::|.|.|.|..   .|.:
 Worm   420 -----------HTDDLSYI--MGVHAFEK---DENEIHLAKSYQEMFMNFVKFGEPGG---GFEM 465

  Fly   527 PNWSPASSYPVEFARLGTKMEDSASIFRLENELMQHRVDFW 567
            ..:..:|.:  .|....|..|.|:.....|.|:    :.:|
 Worm   466 STFENSSYF--NFYWNETTGEKSSMKTNFEKEI----IKYW 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_001303565.1	COesterase	36..567	CDD:278561	125/559 (22%)
		Aes	<116..>254	CDD:223730	41/145 (28%)
cest-6	NP_501070.1	Abhydrolase	25..500	CDD:389770	125/559 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810