Protein Alignment CG6414 and cest-4

DIOPT Version :9

• Sequence 1: NP_001303565.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_501043.1
• Gene: cest-4 / 177445
• WormBaseID: WBGene00015930
• Length: 592
• Species: Caenorhabditis elegans
• Alignment Length: 545
• Identity: 121/545 - (22%)
• Similarity: 204/545 - (37%)
• Gaps: 121/545 - (22%)

  Fly    56 FMGVPYAEPPLDDLRFRPPVPKAPWEGERLAIKDAPICLQRDPFRRDMILEGSEDCLYLNVYTPE 120
            |..:|.|:||:..|||:.|.|...|.|.|.|....|.|:..............||||::|::|.:
 Worm    47 FKHIPLAKPPIGKLRFQKPEPPEKWTGVRNAKAYGPACISNSSVSTSPQKWIDEDCLHINIFTSD 111

  Fly   121 RPRTNGSLPVMVWFHGGGWQCGSGISSFYGPDFLL----DHDIVLVSANFRLGPLG-FLSTETLD 180
            :...:....|:.:|||||....|.:  .:...:||    :.|:::....||||... |:..:...
 Worm   112 KCLKSKDCAVVTYFHGGGLMYDSAV--MFNDTYLLGTFVNQDVIIAIPAFRLGIFSHFVVEDQSI 174

  Fly   181 CPGNNGLKDQLEVLHWVRANIASFGGDPNSVTVFGESAGGASVTYHMLSEK---SRGLLHRGIA- 241
            .|.|..|.|.|..:.:|:..|.:|||:....|:.|.|.||:.|.....|.|   ...|..:.|.
 Worm   175 APTNLALYDILLGVEFVKNEIHNFGGNNQKNTIMGHSYGGSIVNILTFSSKINHDLSLFQQSICM 239

  Fly   242 QSGTYFNPWAQPAHKGVAAGRATKLAQIVGCGNAGEWPEK----------LECLRKKPAEDIV-- 294
            .||..|....      :...:..:.|:..||.......:|          ::||:.|.|.:::
 Worm   240 SSGHDFETLE------IQIQKTNRFAKHAGCTVPSIIEKKMTTRQSDLYRMKCLQNKDALELLRV 298

  Fly   295 -ASLYDMFVWDFDPMIPFPPVVEPEHDGAFLTVAPRQAAKPHGLQLPLMVGATAEEGLLKTAALL 358
             ..|.|.....:..::...|:::.         .|.|.......::|::.|.|..| :..:.|..
 Worm   299 QRLLEDEGYPTYGYLVQREPLIQE---------IPYQEFMKSPKKIPMLTGCTRYE-MDHSPAPK 353

  Fly   359 NLPQLLAEFKSQFEQVLPVVLNY-DHHDDSVRQTITQRIESFYFKSGHDYDKANHQNLTDLISDG 422
            .:.|.|.     ||....|.:.: ...||.|                  |:..||.:.|..|.
 Worm   354 PIGQALG-----FENPEEVYMKFRKDWDDEV------------------YEFGNHSDETQAIM-- 393

  Fly   423 WFVAGIDEYLRLRMSQEDVAPTYVYLFDHKGAASFTEIFKGGRNEFYGACHAEELQYLFPIGREL 487
                 :...:|:........|.|:|.:.:...|.                |.::|.||..:.|
 Worm   394 -----VQVRVRVNNLLSKNVPAYLYEYTYPKHAR----------------HTDDLFYLMGVHR-- 435

  Fly   488 FVSAVPTQKD---LELRELMLHLWVSFAKTGNPNPTNVSFHLPNWSPASSYPV-------EFARL 542
                  .:||   :||.::...::::|||.|:|..   .|.|.|....|.|.|       |..::
 Worm   436 ------FEKDENEIELGKVYETIFMNFAKFGDPKE---GFELANAENESYYEVYWDGETGERPQM 491

  Fly   543 GTKMEDSASIFRLENELMQHRVDFW 567
            .||.|:..             :::|
 Worm   492 KTKFEEKI-------------INYW 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_001303565.1	COesterase	36..567	CDD:278561	120/543 (22%)
		Aes	<116..>254	CDD:223730	39/146 (27%)
cest-4	NP_501043.1	Abhydrolase	28..503	CDD:389770	120/543 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810