Protein Alignment CG6414 and cest-5.2

DIOPT Version :9

• Sequence 1: NP_001303565.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_501021.3
• Gene: cest-5.2 / 177428
• WormBaseID: WBGene00015284
• Length: 583
• Species: Caenorhabditis elegans
• Alignment Length: 565
• Identity: 120/565 - (21%)
• Similarity: 228/565 - (40%)
• Gaps: 130/565 - (23%)

  Fly    41 IGRHLTTHNGRHMRAFMGVPYAEPPLDDLRFRPPVPKAPWEGERLAIKDAPICLQRDPFRRDMIL 105
            :||.....:|:: :.|..:|:|:||:..|||:.|.....|.|...|.:..|.|:....:.:....
 Worm    28 LGRLEGKQSGKY-QLFRRIPFAKPPIGTLRFQKPESAEKWNGVWNATEYGPACMSNSTWTQSPQK 91

  Fly   106 EGSEDCLYLNVYTPERPRTNGSLPVMVWFHGGGWQCGSGISSFYGPDFLLD----HDIVLVSANF 166
            ...||||::|::|.::...:....|:|:.|||.....|.:  .:...|||:    .|::||...|
 Worm    92 WVDEDCLHVNIFTSDKCLKSKDCAVVVYIHGGEIVFDSAV--MFNDTFLLESFVKQDVILVIPAF 154

  Fly   167 RLGPLGFLSTETLD-CPGNNGLKDQLEVLHWVRANIASFGGDPNSVTVFGESAGGASVTYHMLS- 229
            |||.....:....: .|.|..|.|.:....:|::.|.:||||...:|:||.|.||...:....|
 Worm   155 RLGIFSHFTVHDQNIAPNNLALYDIILAQEFVKSEIHNFGGDIQKITLFGHSYGGTIASMMAFSS 219

  Fly   230 --EKSRGLLHRGIAQSGT-YFNPWAQPAHKGVAAGRATKLAQIVGCG---------NAGEWPEK- 281
              .:...|..|.|..|.. ||:...:...      |:.::.:..||.         |..: .||
 Worm   220 EINQDLSLFQRIIVMSANQYFDTLEEQIE------RSDRVVKHAGCSVPTNLARKMNRSQ-KEKY 277

  Fly   282 -LECLRKKPAEDIVA---SLYDMFVWDFDPMI---P-FPPVVEPEHDGAFLTVAPRQAAKPHGLQ 338
             ::||:|....::::   ||.:....|...::   | ||.|...|     :..:|:        .
 Worm   278 MMKCLQKLSGMELLSVQRSLEEAGYPDIGNLVLRGPLFPDVTSLE-----MLESPK--------M 329

  Fly   339 LPLMVGATAEEGLLKTAALLNLPQLLAEFKSQFEQVLPVV------LNYDHHDDSVRQTITQRIE 397
            :|::.|.|                   :|:|..|.....:      .|....|:..|:.:...|
 Worm   330 IPMLAGCT-------------------KFESDDEDETHFIGKHFGLENPIECDEKYRKDLENGI- 374

  Fly   398 SFYFKSGHDYDKANHQNLTDLISDGWFVAGIDEYLRLRMSQEDVAPTYVYLFDHKGAASFTEIFK 462
                     :|:.||.:.|..|.       :...||:...::...|.|:|.|.:.
 Worm   375 ---------FDRQNHSDKTQAIM-------VPTKLRVDQLRKHGVPAYLYEFTYP---------- 413

  Fly   463 GGRNEFYGACHAEELQYLFPIGRELFVSAVPTQKD---LELRELMLHLWVSFAKTGNPNPTNVSF 524
              ::.|    |.::|.|:..|.        |.:||   ..|.::..::.::|.|.|.|   .:.|
 Worm   414 --KHAF----HTDDLYYIMGIH--------PFEKDENEEHLEKVYRNMLINFIKFGEP---GMGF 461

  Fly   525 HLPNWSPASSYPV-------EFARLGTKMEDSASIFRLENELMQH 562
            .:.:.:.::.:.:       :..|:..:.|::.:.:.|: |:|::
 Worm   462 EMSDLNESTYFEIYWNETTGQKPRMRKRFEENITNYWLK-EMMEY 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_001303565.1	COesterase	36..567	CDD:278561	120/565 (21%)
		Aes	<116..>254	CDD:223730	40/146 (27%)
cest-5.2	NP_501021.3	Abhydrolase	23..498	CDD:389770	117/555 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810