Protein Alignment CG6414 and cest-25

DIOPT Version :9

• Sequence 1: NP_001303565.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_497609.1
• Gene: cest-25 / 175390
• WormBaseID: WBGene00022178
• Length: 550
• Species: Caenorhabditis elegans
• Alignment Length: 516
• Identity: 153/516 - (29%)
• Similarity: 236/516 - (45%)
• Gaps: 42/516 - (8%)

  Fly    34 LSHGGWLIGRHLTTHNGRHMRAFMGVPYAEPPLDDLRFRPPVPKAPWEGERLAIKDAPICLQRDP 98
            |:..|.:.||.|.....:.:.||.|:|||.||:.:|||..|.|...|...|.........:|:|.
 Worm    20 LTSYGPIEGRRLIHEGEKQVDAFQGIPYAAPPIGNLRFALPQPHEKWTEVRETKSFGARGIQKDH 84

  Fly    99 FRRDMILEGSEDCLYLNVYTPE-RPRTNGSLPVMVWFHGGGWQCGSGISSFYGPDFLLDH----D 158
            .........|||.|.||::||. .|:.....||:::.||||:...|  :..||...:..|    |
 Worm    85 VLSPKTSPQSEDNLTLNIFTPVWTPKNETGFPVILYIHGGGFVSDS--AHKYGDMSICQHLVTKD 147

  Fly   159 IVLVSANFRLGPLGFLSTETLDCPGNNGLKDQLEVLHWVRANIASFGGDPNSVTVFGESAGGASV 223
            :|:|:..:|||.|||.:|.....|.|..|.|.:..|.||:.||..|.||||::|:.|:|||||||
 Worm   148 VVVVTIQYRLGFLGFWTTGDSSIPDNVALHDMVFALKWVKENIGLFNGDPNNITLMGQSAGGASV 212

  Fly   224 TYHMLSEKSRGLLHRGIAQSGTYFNPWA-QPAHKGVAAGRATKLAQIVGCGNAGEWPEKLECLRK 287
            .:..:|..||.|..:.|...|.....|| .|........||.::....|. |..:|.||   ||:
 Worm   213 DFLSISPVSRDLFQKVIPMGGNASCSWAIHPRPLNACRNRAQEIGVFDGM-NTLDWVEK---LRE 273

  Fly   288 KPAEDIVASLYDMFVWD--FDPMIPFPPVVEPEHDGAFLTVAPRQAAKPHGLQLPLMVGATAEEG 350
            .|| |..||..:|...|  .||.:    ::.|::|..|:. .|....:......|.::|....||
 Worm   274 LPA-DKFASALNMEAVDTKTDPEL----LIGPKYDNLFIP-RPVMELRKEAPMKPRLLGCAKSEG 332

  Fly   351 LLKTAALLNLPQLLAEFKSQF-----EQVLPVVLNYDHHDDSVRQTITQRIESFYFKSGHDYDKA 410
            |:.....||....|...:...     |::.|:... |:.:.::.:.|         :.|.|:.|.
 Worm   333 LVFAFFGLNTKHPLHAVQQDVSAILSEKLFPLKAR-DYQEKALEKLI---------EIGTDHSKE 387

  Fly   411 NHQN-LTDLISDGWFVAGIDEYLRLRMSQEDVAPTYVYLFDHKGAASFTEIFKGGRNEFYGACHA 474
            ..|. :.||..|.:...||.:.:...:..:...|.|:|.||:....::.  ..|.:..|..|.|.
 Worm   388 EWQRAMVDLKGDSFLNVGIQQNVLDVLETQPSTPIYMYSFDYCNPKAYG--IMGFKLPFKDATHC 450

  Fly   475 EELQYLFPIGRELFVSAVPTQKDLELRELMLHLWVSFAKTGNPN--PTNVSFHLPNWSPAS 533
            .::.|:  :|..:..|....::|.::.|:...||.:|||.||||  ..:|:.....|.||:
 Worm   451 TDISYV--VGNHIVNSFDFNEEDYKMIEITTRLWTNFAKYGNPNGEGDDVAHLEEKWEPAT 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_001303565.1	COesterase	36..567	CDD:278561	152/514 (30%)
		Aes	<116..>254	CDD:223730	54/143 (38%)
cest-25	NP_497609.1	COesterase	18..536	CDD:365897	153/516 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	221	1.000	Domainoid score	I1491
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm14771
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.710