Protein Alignment CG6414 and ace-2

DIOPT Version :10

• Sequence 1: NP_570089.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_491141.1
• Gene: ace-2 / 171905
• WormBaseID: WBGene00000036
• Length: 629
• Species: Caenorhabditis elegans
• Alignment Length: 565
• Identity: 149/565 - (26%)
• Similarity: 232/565 - (41%)
• Gaps: 123/565 - (21%)

  Fly    40 LIGRHLTTH------------------------------------------NGRHMRAFMGVPYA 62
            :||||||.|                                          :|..:.||:|||||
 Worm     5 VIGRHLTYHVFCQFALVTLFIVRRIEPRSIVRGDHVVHTPLGTIRGVGQTFDGAKVSAFLGVPYA 69

  Fly    63 EPPLDDLRFRPPVPKAPWEGERLAIKDAPICLQRDPFRRDMILEG-----------------SED 110
            :||:...||:.......|.||..|...|..|.        :.::.                 |||
 Worm    70 KPPIGSRRFKMAEMIDRWSGELEARTLAKTCY--------LTIDSAFPQFPGAEMWNPPGAISED 126

  Fly   111 CLYLNVYTPERPRTNGSLPVMVWFHGGGWQCGS-GISSFYGPDFLLDHDIVLVSANFRLGPLGFL 174
            ||.:|::.||  ..:||  ||||.:|||:..|: .:..:.|..|......::|:.|:||||.|||
 Worm   127 CLNMNIWVPE--DHDGS--VMVWIYGGGFFSGTPSLDLYSGSVFAAKEHTIVVNVNYRLGPFGFL 187

  Fly   175 STETLDCP--GNNGLKDQLEVLHWVRANIASFGGDPNSVTVFGESAGGASVTYHMLSEKSRGLLH 237
            .... |.|  ||.||.||...|.||..||.:||||.:.||:||||||.||.|.|:.:..|.....
 Worm   188 YFGD-DSPIQGNMGLMDQQLALRWVHENIGAFGGDRSRVTLFGESAGSASTTAHLFAPNSHKYFR 251

  Fly   238 RGIAQSGTYFNPWAQPAHKGVAAGRATKLAQIVGCGNAGEWPEK---LECLRKKPAEDIVASLYD 299
            ..||:||:..|.||. |........:.:||:.|.|.:    |:.   ::|||..||. :|.:..|
 Worm   252 NIIAKSGSIINSWAS-ATPPTMLDLSFRLAKKVNCSS----PDMNAIVKCLRSVPAH-LVQAEAD 310

  Fly   300 MFVWDFDPMIPFPPVVEPEHDGAFL--TVAPRQAAKPHGLQLPLMVGATAEEGLLKTAALLNLPQ 362
            ....|..|.:.| ..|....|..|.  .|..:.|.|.....:.::.|:..:||.......::||:
 Worm   311 NISGDIGPPMTF-AYVPVSSDANFFQGDVFQKLANKQFKKDVNIIFGSVKDEGTYWLPYYMSLPK 374

  Fly   363 LLAEFKSQFEQVLP---VVLNYDHHDDSVRQTITQRIESFYFKSG--------HDYDKANHQNLT 416
            ....|........|   .::..||:::|:|..:.      ||...        :.|:..:..|:.
 Worm   375 YGFAFNHTISAEDPHNRALITRDHYEESMRAFMP------YFAGSKLVLNAFMNSYEHVSTSNVP 433

  Fly   417 D---------LISDGWFVAGIDEYLRLRMSQEDVAPTYVYLFDHKGAASFTEIFKGGRNEFYGAC 472
            :         .:.|.:|...:.::..| :|.......|:|.|.::.:|:       ...::.|..
 Worm   434 EERYRDGVARFLGDLFFTCSLIDFADL-ISDNIFGNVYMYYFTYRSSAN-------PWPKWMGVM 490

  Fly   473 HAEELQYLF--PIGRELFVSAVPTQKDLELRELMLHLWVSFAKTG 515
            |..|::|.|  |..|.........:.:..|..:::.:|.:||.||
 Worm   491 HGYEIEYAFGQPYWRPHLYDQTHLEDEKRLSSIIMQIWANFANTG 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_570089.1	COesterase	28..567	CDD:395084	149/565 (26%)
ace-2	NP_491141.1	COesterase	40..558	CDD:395084	142/530 (27%)