Protein Alignment CG6414 and Ces1e

DIOPT Version :9

• Sequence 1: NP_001303565.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_598421.1
• Gene: Ces1e / 13897
• MGIID: 95432
• Length: 562
• Species: Mus musculus
• Alignment Length: 592
• Identity: 182/592 - (30%)
• Similarity: 270/592 - (45%)
• Gaps: 115/592 - (19%)

  Fly    38 GWLIGRHLTTHN-GRHMRAFMGVPYAEPPLDDLRFRPPVPKAPWEGERLAIKDAPICLQRDPF-- 99
            |.::|::::... .:.:..|:|||:|:|||..|||.||.|..||...:.|....|:|.| ||.
Mouse    32 GKVLGKYISLEGFTQPVAVFLGVPFAKPPLGSLRFAPPQPAEPWSSVKNATSYPPMCFQ-DPVTG 95

  Fly   100 ---------RRDMI-LEGSEDCLYLNVYTPERPRTNGSLPVMVWFHGGGWQCGSGISSFYGPDFL 154
                     |::.| |:.||||||||:|||.....:..||||||.||||...| |.|::.|....
Mouse    96 QIVNDLLTNRKEKIPLQFSEDCLYLNIYTPADLTKSDRLPVMVWIHGGGLVLG-GASTYDGLVLS 159

  Fly   155 LDHDIVLVSANFRLGPLGFLSTETLDCPGNNGLKDQLEVLHWVRANIASFGGDPNSVTVFGESAG 219
            ...::|:|...:|||..||.||......||.|..||:..||||:.|||.|||||.|||:||||||
Mouse   160 THENVVVVVIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALHWVQDNIAKFGGDPGSVTIFGESAG 224

  Fly   220 GASVTYHMLSEKSRGLLHRGIAQSGTYFNPWAQPAHKGVAAG--------RATKLAQIVGCGNAG 276
            |.||:..:||..::.|..|.|::||.           .:.||        .|.|:|.|.||.|..
Mouse   225 GESVSVLVLSPLAKNLFQRAISESGV-----------ALTAGLVKKNTRPLAEKIAVISGCKNTT 278

  Fly   277 EWPEKLECLRKKPAEDIVASLYDMFVWDFD------PMIPFPPVVEPEHDGAFLTVAPRQ-AAKP 334
            . ...:.|||:|..|:::.:...:.::..|      ...||.|.|   .||..|...|.: .|:.
Mouse   279 S-AAMVHCLRQKTEEELLGTTLKLNLFKLDLHGDSRQSHPFVPTV---LDGVLLPKMPEEILAEK 339

  Fly   335 HGLQLPLMVGATAEEGLLKTAALLNLPQLLAEFKSQFEQVLPVVLNYDHHDDSVRQ--------- 390
            :...:|.:||..                     |.:|..:||.::||...|..:.|
Mouse   340 NFNTVPYIVGIN---------------------KQEFGWILPTMMNYPPSDVKLDQMTAMSLLKK 383

  Fly   391 ----------TITQRIESFYFKSGHDYDKANHQNLTDLISDGWFVAGIDEYLRLRMSQEDVAPTY 445
                      .|...||.:.  ...||...|...|.:||.|  .|.|:...:..|..::..||||
Mouse   384 SSFLLNLPEDAIAVAIEKYL--RDKDYTGRNKDQLLELIGD--VVFGVPSVIVSRGHRDAGAPTY 444

  Fly   446 VYLFDHKGAASFTEIFKGGRNEFYGACHAEELQYLF--PIGRELFVSAVPTQKDLELRELMLHLW 508
            :|.|.:  :.||:...|   .:.....|.:|:..:|  ||.|     ...:::::.|.::|:..|
Mouse   445 MYEFQY--SPSFSSEMK---PDTVVGDHGDEIYSVFGAPILR-----GGTSEEEINLSKMMMKFW 499

  Fly   509 VSFAKTGNPNPTNVSFHLPNWSPASSYPVEFARLGTKMEDSASIFRLENELMQHRVDFWRDL--Q 571
            .:||:.||||...    ||:| |.......:.::|...:.:       .:|.:..|.||.:|  :
Mouse   500 ANFARNGNPNGQG----LPHW-PEYDQKEGYLQIGATTQQA-------QKLKEKEVAFWTELLAK 552

  Fly   572 PHLPASH 578
            ..||..|
Mouse   553 KQLPTEH 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_001303565.1	COesterase	36..567	CDD:278561	176/577 (31%)
		Aes	<116..>254	CDD:223730	62/137 (45%)
Ces1e	NP_598421.1	COesterase	25..546	CDD:278561	176/577 (31%)
		Aes	44..>242	CDD:223730	91/199 (46%)
		Prevents secretion from ER. /evidence=ECO:0000255	559..562		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6088
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.760