Protein Alignment CG6414 and ache

DIOPT Version :10

• Sequence 1: NP_570089.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_571921.1
• Gene: ache / 114549
• ZFINID: ZDB-GENE-010906-1
• Length: 634
• Species: Danio rerio
• Alignment Length: 541
• Identity: 166/541 - (30%)
• Similarity: 241/541 - (44%)
• Gaps: 98/541 - (18%)

  Fly    38 GWLIGRHLTTHNGRHMRAFMGVPYAEPPLDDLRFRPPVPKAPWEGERLAIKDAPICLQ------- 95
            |.:.|..|...:..|:.||:|:||||||:...||:...||.||.....|.:.:..|.|
Zfish    36 GRVQGTRLPVPDRSHVIAFLGIPYAEPPIGKRRFKRAEPKKPWNNVFEAKEFSNACYQFVDTSYP 100

  Fly    96 ----RDPFRRDMILEGSEDCLYLNVYTPERPRTNGSLPVMVWFHGGGWQCGSGISSFYGPDFL-L 155
                .:.:..:.::  |||||||||:.|..||.. :|.||||.:|||:..||.....|...:| .
Zfish   101 GFPGIEMWNPNRVM--SEDCLYLNVWVPPTPRPQ-NLTVMVWIYGGGFYSGSSSLDVYDGRYLAY 162

  Fly   156 DHDIVLVSANFRLGPLGFLSTE-TLDCPGNNGLKDQLEVLHWVRANIASFGGDPNSVTVFGESAG 219
            ...:|:||.|:|:|..|||:.. :.|.|||.||.||...|.||:.||..|||:|..||:||||||
Zfish   163 TEKVVVVSMNYRVGAFGFLALNGSSDAPGNVGLYDQRLALQWVQENIHFFGGNPKQVTIFGESAG 227

  Fly   220 GASVTYHMLSEKSRGLLHRGIAQSGTYFNPWAQPAHKGVAAGRATKLAQIVGCGNAGEWPEKLEC 284
            .|||..|:||..||.|..|.|.|||....|||.... ..|..|.|||.::||| ..|...|.::|
Zfish   228 AASVGMHVLSPDSRPLFTRAILQSGVPNTPWATVTF-DEARRRTTKLGKLVGC-TWGNDTELIDC 290

  Fly   285 LRKKPAEDIVASLYDMFVWDFDPMIPFPPVVEPEHDGAFLTVAPRQAAKPHGLQ-LPLMVGATAE 348
            ||.|..::::...:.:..|.......|.|||    ||.|....|.........: ..:::|...:
Zfish   291 LRNKHPQELIDQEWQVLPWSSLFRFSFVPVV----DGVFFPDTPDAMISSGNFKYTQILLGVNQD 351

  Fly   349 EG---LLKTA--------ALLNLPQLLAEFKSQFEQVLPVVLNYDHHDD-SVRQTITQRIESFYF 401
            ||   ||..|        :|::....|...|          :...|.:| .:...|.|..:....
Zfish   352 EGSYFLLYGAPGFSKDNESLISREDFLESVK----------MGVPHANDIGLEAVILQYTDWMDE 406

  Fly   402 KSGHDYDKANHQNLTDLISD-------GWFVAGIDEYLRLRMSQEDVAP---------------- 443
            .:|    :.|...:.|::.|       ..|.....:|..|.......||
Zfish   407 NNG----QKNRDAMDDIVGDQNVICPLQHFAKSYAQYAALHAQSSAAAPGTLGWGNSGPTGYNSG 467

  Fly   444 -----TYVYLFDHKGAASFTEIFKGGRN----EFYGACHAEELQYLF--PIGRELFVSAVPTQKD 497
                 .|:|||||:.:           |    |:.|..|..|::::|  |:.:.|..:|    ::
Zfish   468 NSHGAVYLYLFDHRAS-----------NLAWPEWMGVIHGYEIEFVFGLPLEKRLNYTA----EE 517

  Fly   498 LELRELMLHLWVSFAKTGNPN 518
            .:|...::..|.:||:|||||
Zfish   518 EKLSRRIMRYWANFARTGNPN 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_570089.1	COesterase	28..567	CDD:395084	166/541 (31%)
ache	NP_571921.1	COesterase	27..583	CDD:395084	166/541 (31%)
		AChE_tetra	598..631	CDD:430146